SMILES string
[Na+].[O-]C(=O)CCC(=O)OCC(=O)[C@@]1([C@@]2([C@H]([C@H]3[C@@H]([C@@]4(C(=CC(=O)C=C4)[C@H](C3)C)C)[C@H](C2)O)CC1)C)O
InChI
1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1
InChI key
FQISKWAFAHGMGT-SGJOWKDISA-M
API family
methylprednisolone
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Methylprednisolone hemisuccinate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Methylprednisolone Sodium Succinate
- Methylprednisolone Sodium Succinate for Injection
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B - STOT RE 2
target_organs
Adrenal gland,Immune system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Claudia Druschel et al.
Spine, 38(11), E669-E677 (2013-03-01)
Written mail-out survey. To determine current practice in high-dose methylprednisolone succinate (MPSS) administration for treatment of acute spinal cord injury (SCI) in Germany. Reanalysis of the National Acute Spinal Cord Injury Studies (NASCIS) resulted in criticism of the use of
Lasse Murtomäki et al.
Journal of pharmaceutical sciences, 102(7), 2264-2272 (2013-05-15)
The affinity of a drug to a biological membrane can affect the distribution and the availability of the active compound to its target. Adsorption is usually determined with in vitro distribution studies based on partitioning of the drug between buffer
Hoda Derakhshanian et al.
Canadian journal of physiology and pharmacology, 91(5), 380-385 (2013-05-10)
Glucocorticoid-induced osteoporosis (GIO) is the most common type of secondary osteoporosis. The aim of this study was to compare the efficacy of quercetin, a plant-derived flavonoid, with alendronate in the prevention of GIO. Fifty-six Sprague-Dawley rats were randomly distributed among
Kai-feng Wang et al.
Zhonghua wai ke za zhi [Chinese journal of surgery], 51(5), 426-431 (2013-08-21)
To investigate the effects and apoptosis of intrathecal injection of Methylprednisolone Sodium Succinate (MPss) for acute spinal cord injury (SCI) in New Zealand rabbits. Seventy-two healthy New Zealand rabbits were used for the procedure and were randomly divided into two
Long-term selective IgE-mediated hypersensitivity to hydrocortisone sodium succinate.
G F Calogiuri et al.
Allergologia et immunopathologia, 41(3), 206-208 (2012-09-25)
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