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经验公式（希尔记法）:
C17H19N3
化学文摘社编号:
分子量:
265.35
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
米氮平, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
SMILES string
CN1CCN2C(C1)c3ccccc3Cc4cccnc24
InChI key
RONZAEMNMFQXRA-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
mirtazapine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... ADRA2A(150), ADRA2B(151), ADRA2C(152), HTR2A(3356), HTR2C(3358)
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Mirtazapine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Mirtazapine Tablets
- Mirtazapine Orally Disintegrating Tablets
- Mirtazapine Compounded Oral Suspension, Veterinary
Biochem/physiol Actions
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT1A mediated serotonergic signaling are increased.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral - STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Mirtazapine Orally Disintegrating Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(2), 2980-2980 (2020)
Mirtazapine
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(6), 2976-2976 (2021)
Mirtazapine Compounded Oral Suspension, Veterinary
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(5), 2977-2977 (2019)
Michael Paulzen et al.
Psychopharmacology, 232(4), 807-813 (2014-08-26)
The aim of this study was to investigate the distribution pattern of mirtazapine and its metabolite normirtazapine (N-desmethylmirtazapine) in blood and cerebrospinal fluid (CSF). Concentrations of mirtazapine were measured in blood serum and CSF of 16 patients treated with daily
Katarzyna Kamińska et al.
Pharmacological reports : PR, 66(6), 984-990 (2014-12-03)
The aim of our study was to understand the mechanism of clinical efficacy of the combination of an antidepressant and risperidone in drug-resistant depression. We studied the effect of an antidepressant (mirtazapine) and risperidone (atypical antipsychotic), given separately or jointly
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