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经验公式(希尔记法):
C25H32ClN5O2 · HCl
化学文摘社编号:
分子量:
506.47
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
Nefazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H
SMILES string
O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.Cl
InChI key
DYCKFEBIOUQECE-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
nefazodone
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... HTR2A(3356), HTR2C(3358), SLC6A2(6530), SLC6A4(6532)
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Nefazodone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Nefazodone Hydrochloride Tablets
Biochem/physiol Actions
Novel antidepressant; mixed 5-HT2A serotonin receptor antagonist/serotonin uptake inhibitor.
Other Notes
Sales restrictions may apply.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Electrochemical characterisation of nefazodone hydrochloride and voltammetric determination of the drug in pharmaceuticals and human serum.
Uslu, Bengi, and Sibel A. Ozkan.
Analytica Chimica Acta, 462.1, 49-57 (2002)
Anne-Charlotte Dubbelman et al.
Journal of chromatography. A, 1374, 122-133 (2014-12-02)
The present study investigated the practical use of modern ultra-high performance liquid chromatography (UHPLC) separation techniques for drug metabolite profiling, aiming to develop a widely applicable, high-throughput, easy-to-use chromatographic method, with a high chromatographic resolution to accommodate simultaneous qualitative and
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