所有图片(1)

文件

1478301

USP

奥氮平

Name: 奥氮平
Brand: USP

United States Pharmacopeia (USP) Reference Standard

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别名:

2-甲基-4-（4-甲基-1-哌嗪基）-10H-噻吩并[2,3-b] [1,5]苯并二氮杂

经验公式（希尔记法）:

C₁₇H₂₀N₄S

CAS号:

132539-06-1

分子量:

312.43

Beilstein:

7655141

MDL编号:

MFCD00866702

PubChem化学物质编号:

329750606

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

olanzapine

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

CN1CCN(CC1)C2=Nc3ccccc3Nc4sc(C)cc24

InChI

1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3

InChI key

KVWDHTXUZHCGIO-UHFFFAOYSA-N

基因信息

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356) , HTR2C(3358)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Olanzapine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

Sales restrictions may apply.

1478312

1478323

1478334

BP1060

奥氮平, British Pharmacopoeia (BP) Reference Standard

Y0002177

Olanzapine embonate for peak identification, CRS, European Pharmacopoeia (EP) Reference Standard

PHR2537

PHR2536

PHR2538

象形图

GHS07

警示用语：

Warning

危险声明

H315 - H319

预防措施声明

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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A platinum black-modified microelectrode for in situ olanzapine detection in microliter volumes of undiluted serum.

Rajendra P Shukla et al.

Journal of neural transmission (Vienna, Austria : 1996), 127(2), 291-299 (2020-01-08)

Olanzapine is a thienobenzodiazepine compound. It is one of the newer types of antipsychotic drugs used in the treatment of schizophrenia and other psychotic disorders. Several methods have been reported for analyzing olanzapine in its pure form or combined with

Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression.

Mauricio Tohen et al.

Archives of general psychiatry, 60(11), 1079-1088 (2003-11-12)

Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of antidepressants combined with antipsychotics or mood stabilizers, relatively few controlled studies have examined treatment strategies for bipolar depression. To examine the use of

Olanzapine: a systematic review and meta-regression of the relationships between dose, plasma concentration, receptor occupancy, and response.

Delia Bishara et al.

Journal of clinical psychopharmacology, 33(3), 329-335 (2013-04-24)

To conduct a systematic review examining the relationships between olanzapine dose, clinical outcome, dopamine occupancy, and plasma concentration; and to evaluate the potential for therapeutic drug monitoring. A search using Embase, Medline, and Pubmed was conducted; and the literature was

Olanzapine in pregnancy and breastfeeding: a review of data from global safety surveillance.

Elizabeth Brunner et al.

BMC pharmacology & toxicology, 14, 38-38 (2013-08-02)

Olanzapine use has been reported during pregnancy and breastfeeding, but there are no controlled clinical trials assessing the safety of olanzapine exposure to infants and fetuses. The purpose of this report was to review and analyze prospective post-marketing cases of

Olanzapine for chemotherapy-induced nausea and vomiting: a systematic review.

Christopher M Hocking et al.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(4), 1143-1151 (2014-02-14)

Newer drugs incorporated in prophylactic regimens for chemotherapy-induced nausea and vomiting (CINV) have resulted in significantly reduced rates of this feared complication of cytotoxic chemotherapy. However, both delayed chemotherapy-induced nausea and breakthrough CINV remain difficult areas of management and require

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