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文件

1483152

USP

奥卡西平

Name: 奥卡西平
Brand: USP

United States Pharmacopeia (USP) Reference Standard

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别名:

10,11-二氢-10-氧代-5H-二苯并[b,f]氮杂-5-甲酰胺, 奥卡西平

经验公式（希尔记法）:

C₁₅H₁₂N₂O₂

CAS号:

28721-07-5

分子量:

252.27

MDL编号:

MFCD00865307

PubChem化学物质编号:

329750633

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

oxcarbazepine

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

O=C1CC2=C(C=CC=C2)N(C(N)=O)C3=CC=CC=C31

InChI

1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)

InChI key

CTRLABGOLIVAIY-UHFFFAOYSA-N

基因信息

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Oxcarbazepine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生化/生理作用

抗惊厥药，止痛药。抑制藜芦碱诱导的递质释放。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

Sales restrictions may apply.

PHR2238

PHR3071

吖啶酮, pharmaceutical secondary standard, certified reference material

PHR3294

10,11-二氢-10-羟基卡马西平, pharmaceutical secondary standard, certified reference material

象形图

GHS07

警示用语：

Warning

危险声明

H302

预防措施声明

P264 - P270 - P301 + P312 - P501

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

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索取COA

Oxcarbazepine in the maintenance treatment of bipolar disorder.

A Vasudev et al.

The Cochrane database of systematic reviews, (1)(1), CD005171-CD005171 (2008-02-07)

Some studies have suggested that oxcarbazepine has a role in preventing episode recurrence in bipolar affective disorder. This review attempted to investigate the existing evidence from randomised controlled trials for its use in the maintenance treatment of this illness. To

Safety and efficacy of anticonvulsants in elderly patients with psychiatric disorders: oxcarbazepine, topiramate and gabapentin.

Barbara R Sommer et al.

Expert opinion on drug safety, 6(2), 133-145 (2007-03-21)

Few controlled studies are available to guide the clinician in treating potentially assaultive elderly individuals with psychiatric disorders. Safety concerns limit the use of benzodiazepines and antipsychotic medications in the elderly individual, making anticonvulsants an attractive alternative. This paper reviews

Oxcarbazepine for acute affective episodes in bipolar disorder.

Akshya Vasudev et al.

The Cochrane database of systematic reviews, (12)(12), CD004857-CD004857 (2011-12-14)

Oxcarbazepine, a keto derivative of the 'mood stabiliser' carbamazepine, may have efficacy in the treatment of acute episodes of bipolar disorder. Potentially, it may offer pharmacokinetic advantages over carbamazepine. To review the efficacy and acceptability of oxcarbazepine compared to placebo

Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine.

Gaetano Zaccara et al.

Seizure, 22(7), 528-536 (2013-04-30)

Analysis of overall tolerability and neurological adverse effects (AEs) of eslicarbazepine acetate (ESL), lacosamide (LCM) and oxcarbazepine (OXC) from double-blind, placebo-controlled trials. Indirect comparisons of patients withdrawing because of AEs, and the incidence of some vestibulocerebellar AEs between these three

Oxcarbazepine in the treatment of bipolar disorder: a review.

Wetid Pratoomsri et al.

Canadian journal of psychiatry. Revue canadienne de psychiatrie, 51(8), 540-545 (2006-08-29)

To review the data on the efficacy of oxcarbazepine (OXC) in bipolar disorder (BD) and to provide recommendations for clinicians on the use of this medication in treating BD. Using the terms oxcarbazepine and bipolar disorder, oxcarbazepine and mania, or

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