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Merck
CN

1494920

USP

5-(二氟甲氧基)-2-巯基-1H-苯并咪唑

United States Pharmacopeia (USP) Reference Standard

别名:

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

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关于此项目

经验公式(希尔记法):
C8H6F2N2OS
化学文摘社编号:
分子量:
216.21
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI key

HJMVPNAZPFZXCP-UHFFFAOYSA-N

SMILES string

FC(F)Oc1ccc2[nH]c(S)nc2c1

InChI

1S/C8H6F2N2OS/c9-7(10)13-4-1-2-5-6(3-4)12-8(14)11-5/h1-3,7H,(H2,11,12,14)

grade

pharmaceutical primary standard

API family

pantoprazole

manufacturer/tradename

USP

mp

239-243 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

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Application

Pantoprazole Related Compound C USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monograph such as Pantoprazole Sodium

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ganta Madhusudhan Reddy et al.
Journal of pharmaceutical and biomedical analysis, 45(2), 201-210 (2007-07-17)
Six impurities in pantoprazole sodium bulk drug substance were detected by a simple high performance liquid chromatographic method (HPLC) whose area percentage ranged from approximately 0.05 to 0.34%. Liquid chromatography-mass spectrometry (LC-MS) was performed to identify the molecular weight of
S-arylation of mercaptobenzimidazoles using Cu (I) catalysts-experimental and theoretical observations.
Sekar, Ramkumar, et al.
Tetrahedron Letters, 52.26, 3347-3352 (2011)

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