产品名称
己酮可可碱, United States Pharmacopeia (USP) Reference Standard
InChI key
MQGNNJQTNFHNHK-UHFFFAOYSA-N
SMILES string
CN1C=NC2C1C(=O)N(CCCCC(C)=O)C(=O)N2C
InChI
1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8,10-11H,4-7H2,1-3H3
grade
pharmaceutical primary standard
API family
pentoxifylline
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
正在寻找类似产品? 访问 产品对比指南
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Pentoxifylline USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Pentoxifylline Compounded Oral Suspension
- Pentoxifylline Extended-Release Tablets
Biochem/physiol Actions
Phosphodiesterase inhibitor; inhibits synthesis of tumor necrosis factor α (TNF-α).
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Lact.
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
涉药品监管产品
此项目有
R Parker et al.
Alimentary pharmacology & therapeutics, 37(9), 845-854 (2013-03-16)
Acute alcoholic hepatitis (AH) is a severe manifestation of alcoholic liver disease with a grave prognosis. Pentoxifylline, an oral antitumour necrosis factor agent, has been reported to reduce mortality and incidence of hepatorenal syndrome (HRS) in severe alcoholic hepatitis (SAH).
Dan Shan et al.
The Cochrane database of systematic reviews, 2(2), CD006800-CD006800 (2012-02-18)
Diabetic kidney disease (DKD) is associated with increased morbidity and mortality, mostly relating to cardiovascular complications. The relevance of inflammation in the pathogenesis of DKD has been investigated in recent years, and it has been shown that inflammatory markers are
Andrew B Jull et al.
The Cochrane database of systematic reviews, 12, CD001733-CD001733 (2012-12-14)
Healing of venous leg ulcers is improved by the use of compression bandaging but some venous ulcers remain unhealed, and some people are unsuitable for compression therapy. Pentoxifylline, a drug which helps blood flow, has been used to treat venous
Khalid N Haque et al.
The Cochrane database of systematic reviews, (10)(10), CD004205-CD004205 (2011-10-07)
Mortality and morbidity due to neonatal sepsis and necrotizing enterocolitis (NEC) is high despite the use of potent antimicrobial agents. Agents that modulate inflammation may improve outcomes. Pentoxifylline, a phosphodiesterase inhibitor, is one such agent. The primary objectives were to
Zahra Nasiri-Toosi et al.
European journal of clinical pharmacology, 69(5), 1057-1073 (2012-11-28)
Drug-induced nephrotoxicity is one of the most common side effects of medications and accounts for about 20 % of hospital admissions for acute kidney injury (AKI). Some possible pharmacologic mechanisms of pentoxifylline (PTX) that suggest it as a candidate to
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持