产品名称
5,5-二苯基海因 钠盐, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C15H12N2O2.Na/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12;/h1-10H,(H2,16,17,18,19);/q;+1/p-1
SMILES string
[Na]N1C(=O)NC(C1=O)(c2ccccc2)c3ccccc3
InChI key
FJPYVLNWWICYDW-UHFFFAOYSA-M
grade
pharmaceutical primary standard
API family
phenytoin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
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Biochem/physiol Actions
减少癫痫大发作的发生率；可能通过 Na+、K+ 和 Ca2+ 通道的影响而稳定可兴奋膜。
Reduces incidence of grand mal seizures; appears to stabilize excitable membranes.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Phenytoin sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
General description
Phenytoin sodium is an anti-epileptic drug, which belongs to the hydantoin family.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Courtenay M and Griffiths M
Independent and Supplementary Prescribing: An Essential Guide null
Lemke.LT and Williams.AD
Foye's Principles of Medicinal Chemistry (2012)
Maria B Rabaglino et al.
BMC genomics, 15, 1001-1001 (2014-11-21)
Major changes in gene expression occur in the fetal brain to modulate the function of this organ postnatally. Thus, factors can alter the genomics of the fetal brain, predisposing to neurological disorders later in life. We hypothesized that the physiological
Shareef Ahmed et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 30(10), 823-830 (2014-08-29)
To determine whether penetrating scleral or corneal injury can enhance intraocular penetration of systemic moxifloxacin, vancomycin, and ceftazidime. Thirty rabbits were divided into 3 groups for each antibiotic and then further subdivided to receive either scleral or corneal injury to
Misty Good et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G1021-G1032 (2014-04-20)
Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal disease in premature infants and develops partly from an exaggerated intestinal epithelial immune response to indigenous microbes. There has been interest in administering probiotic bacteria to reduce NEC severity
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