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Merck
CN

1589007

USP

乙胺嘧啶

United States Pharmacopeia (USP) Reference Standard

别名:

6-乙基-5-(4-氯苯基)-2,4-嘧啶二胺

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关于此项目

经验公式(希尔记法):
C12H13ClN4
化学文摘社编号:
分子量:
248.71
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
219864
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产品名称

乙胺嘧啶, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

SMILES string

CCC1=NC(N)=NC(N)=C1C2=CC=C(Cl)C=C2

InChI key

WKSAUQYGYAYLPV-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

pyrimethamine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Pyrimethamine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Pyrimethamine Tablets
  • Sulfadoxine and Pyrimethamine Tablets
  • Pyrimethamine Compounded Oral Suspension

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The stem bark of Polyalthia oliveri was screened for its chemical constituents using liquid chromatography high resolution mass spectrometry resulting in the isolation of three indolosesquiterpene alkaloids named 8α-polyveolinone (1), N-acetyl-8α-polyveolinone (2) and N-acetyl-polyveoline (3), together with three known compounds
Abdoulaye Gaye et al.
The American journal of tropical medicine and hygiene, 92(3), 648-652 (2015-01-28)
Direct skin feeding experiments are sensitive assays to determine human infectiousness to mosquitoes but are rarely used in malaria epidemiological surveys. We determined the infectiousness of inhabitants of a malaria hypoendemic area in Senegal. Gametocyte prevalence by microscopy was 13.5%
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Malaria journal, 13, 358-358 (2014-09-14)
In sub-Saharan Africa, artemisinin-based combination therapy (ACT) and injectable artesunate are the first-line treatments for uncomplicated and severe Plasmodium falciparum malaria, respectively. However, recent studies suggest that delayed anaemia is associated with these treatments in non-immune travellers. This paper aimed
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Drug metabolism and pharmacokinetics, 29(3), 266-271 (2014-01-07)
Telaprevir-based triple therapy is a highly effective treatment for chronic hepatitis C. However, adverse reactions include reversible and dose-dependent elevation of serum creatinine levels. We speculated that this effect reflects inhibition of the renal organic cation transporters hOCT2, hMATE1, and
Sarmad N Mageed et al.
Antimicrobial agents and chemotherapy, 58(11), 6345-6353 (2014-07-23)
Toxoplasma gondii is a major food pathogen and neglected parasitic infection that causes eye disease, birth defects, and fetal abortion and plays a role as an opportunistic infection in AIDS. In this study, we investigated pantothenic acid (vitamin B5) biosynthesis

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