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经验公式(希尔记法):
C20H24N2O2 · 0.5H2O4S · H2O
化学文摘社编号:
分子量:
391.47
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6113937
产品名称
奎宁 半硫酸盐 一水合物, United States Pharmacopeia (USP) Reference Standard
InChI
1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
SMILES string
O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
InChI key
ZHNFLHYOFXQIOW-LPYZJUEESA-N
grade
pharmaceutical primary standard
API family
quinine
mol wt
monograph mol wt. 782.94
manufacturer/tradename
USP
mp
~225 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Quinine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Quinine Sulfate Capsules
- Quinine Sulfate Tablets
General description
(C20H24N2O2)2 . H2SO4 . 2H2O
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Quinine sulfate is the sulfate salt of quinine, an alkaloid, obtained from the bark of Cinchona species.
Quinine sulfate is the sulfate salt of quinine, an alkaloid, obtained from the bark of Cinchona species.
Biochem/physiol Actions
钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂;最初从南美树木的金鸡纳科中分离出来的生物碱。
钾通道阻滞剂。抗疟疾
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Quinine sulfate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 37(3), 3818-3818 (2018)
Determination of quinine sulfate in extemporaneous suspension by stability indicating high performance liquid chromatography
Jeadkong S, et al.
Research Journal of Pharmacy and Technology, 10(6), 1603-1610 (2017)
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