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Merck
CN

1609603

USP

沙美特罗 羟萘甲酸盐

United States Pharmacopeia (USP) Reference Standard

别名:

(±) 4-羟基-a1-[[[6-(4-苯基丁氧基)己基]氨基]间-乙基]-1,3-苯二甲醇 羟萘甲酸盐, GR 33343X 羟萘甲酸盐

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关于此项目

经验公式（希尔记法）:
C25H37NO4 · C11H8O3
化学文摘社编号:
94749-08-3
分子量:
603.75
MDL编号:
MFCD00897708
UNSPSC代码:
41116107
PubChem化学物质编号:
329751072
NACRES:
NA.24

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等级

pharmaceutical primary standard

API类

salmeterol

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

OC(=O)c1ccc2ccccc2c1O.OCc3cc(ccc3O)C(O)CNCCCCCCOCCCCc4ccccc4

InChI

1S/C25H37NO4.C11H8O3/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21;12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2;1-6,12H,(H,13,14)

InChI key

XTZNCVSCVHTPAI-UHFFFAOYSA-N

基因信息

human ... ADRB2(154)

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Salmeterol xinafoate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Fluticasone Propionate and Salmeterol Inhalation Aerosol®
  • Fluticasone Propionate and Salmeterol Inhalation Powder
  • Salmeterol Inhalation Powder
  • Salmeterol Xinafoate

生化/生理作用

β2-肾上腺素能受体激动剂。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

法律信息

Aerosol is a registered trademark of Cytec Technology Corp.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R N Brogden et al.
Allergologia et immunopathologia, 20(2), 72-84 (1992-03-01)
Salmeterol xinafoate, like salbutamol (albuterol), is a saligenin derivative, and a selective beta 2-adrenoceptor agonist. It produces bronchodilation for at least 12 hours following inhalation of a single 50 micrograms dose. Salmeterol is intended for regular twice-daily treatment of reversible
R N Brogden et al.
Drugs, 42(5), 895-912 (1991-11-01)
Salmeterol xinafoate, like salbutamol (albuterol), is a saligenin derivative, and a selective beta 2-adrenoceptor agonist. It produces bronchodilation for at least 12 hours following inhalation of a single 50 micrograms dose. Salmeterol is intended for regular twice-daily treatment of reversible
A Jouyban-Gharamaleki et al.
International journal of pharmaceutics, 216(1-2), 33-41 (2001-03-29)
The mole fraction solubility of salmeterol xinafoate was determined in various concentrations of dioxane in aqueous binary mixture. Maximum solubility was observed in 90% v/v dioxane and solubility parameter of the solute was estimated from solubility peak equal to 24.99

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