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经验公式（希尔记法）:
C10H9AgN4O2S
化学文摘社编号:
分子量:
357.14
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
SMILES string
Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2
InChI key
UEJSSZHHYBHCEL-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
sulfadiazine
manufacturer/tradename
USP
mp
285 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Silver sulfadiazine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Silver Sulfadiazine Cream
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Frederick W Fuller
Journal of burn care & research : official publication of the American Burn Association, 30(3), 464-470 (2009-04-08)
Silver sulfadiazine cream has an enviable safety record in burn treatment. However, it side effects, exemplified by allergic reactions to its sulfadiazine moiety, silver staining of the treated burn wound, hyperosmolality, methemoglobinemia, and hemolysis due to a congential lack of
Myth: silver sulfadiazine is the best treatment for minor burns.
J Y Chung et al.
The Western journal of medicine, 175(3), 205-206 (2001-08-31)
M Prosdocimi et al.
Minerva medica, 103(6), 533-539 (2012-12-12)
Diabetes-related chronic cutaneous lesions are a serious and common problem, as well as a major cause for hospital admissions, although no general consensus has been reached on the best available treatment for this frequent pathological condition. The primary objective of
Use of silver sulfadiazine in Stevens-Johnson syndrome.
M L Frenia et al.
The Annals of pharmacotherapy, 28(6), 736-737 (1994-06-01)
Andrew C Miller et al.
Journal of the American Academy of Dermatology, 66(5), e159-e165 (2010-08-21)
For decades silver-containing antibiotics such as silver sulfadiazine (SSD) have been applied as standard topical therapy for patients with partial-thickness burns and venous stasis ulcers. This evidence-based review intends to answer the following research question: in ambulatory patients with partial-thickness
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