1708707
USP
丙戊酸
United States Pharmacopeia (USP) Reference Standard
别名:
2-丙基戊酸, 丙戊酸
等级
pharmaceutical primary standard
API类
valproic acid
制造商/商品名称
USP
折射率
n20/D 1.425 (lit.)
沸点
220 °C (lit.)
密度
0.9 g/mL at 25 °C (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
CCCC(C(O)=O)CCC
InChI
1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
InChI key
NIJJYAXOARWZEE-UHFFFAOYSA-N
基因信息
human ... ALDH5A1(7915)
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一般描述
本产品按照现行药典要求提供和指定。所有为支持本产品而提供的信息，包括 SDS 和任何产品信息小册子，均由药典颁发机构制定和发布。如需进一步的信息和支持，请访问现行药典网站。如需进一步信息和支持，请访问现行药典网站。
应用
丙戊酸USP参考标准品的预期用途是USP规定的指定质量测试和检测。也用于USP各论，例如：
- 丙戊酸钠
- 丙戊酸钠缓释胶囊
- 丙戊酸钠迟释片
- 丙戊酸钠缓释片
- 丙戊酸钠注射液
- 丙戊酸
- 丙戊酸胶囊
生化/生理作用
抗惊厥药，同时还具有双相障碍症情绪稳定剂的功效
分析说明
这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。
其他说明
可能适用相应的销售限制。
警示用语：
Danger
危险分类
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1A - Skin Irrit. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
231.8 °F - closed cup
闪点(°C)
111 °C - closed cup
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The mood stabilizers lithium and valproic acid (VPA) are traditionally used to treat bipolar disorder (BD), a severe mental illness arising from complex interactions between genes and environment that drive deficits in cellular plasticity and resiliency. The therapeutic potential of
Brian L Le et al.
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The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-CoV-2 differential gene expression signatures derived from publicly available data. We utilized three independent published studies to acquire or
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Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an
Radu M Nanau et al.
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Valproic acid is a widely-used first-generation antiepileptic drug, prescribed predominantly in epilepsy and psychiatric disorders. VPA has good efficacy and pharmacoeconomic profiles, as well as a relatively favorable safety profile. However, adverse drug reactions have been reported in relation with
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