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1724500

USP

齐多夫定

Name: 齐多夫定
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

3′-叠氮-3′-脱氧胸苷, AZT, ZDV, 叠氮胸苷, 齐多夫定

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关于此项目

经验公式（希尔记法）:

C₁₀H₁₃N₅O₄

化学文摘社编号:

30516-87-1

分子量:

267.24

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329751524

MDL number:

MFCD00006536

Beilstein/REAXYS Number:

3595791

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属性

grade

pharmaceutical primary standard

API family

zidovudine

manufacturer/tradename

USP

mp

113-115 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O

InChI

1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1

InChI key

HBOMLICNUCNMMY-XLPZGREQSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Zidovudine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Abacavir, Lamivudine and Zidovudine Tablets
Lamivudine and Zidovudine Tablets
Zidovudine
Zidovudine Capsules
Zidovudine Injection
Zidovudine Oral Solution
Zidovudine Tablets

Biochem/physiol Actions

对 HIV-1 病毒有效的逆转录酶抑制剂。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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pictograms

GHS08

signalword

Warning

hcodes

H341,H351

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 2 - Muta. 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study.

Youko Suehiro et al.

British journal of haematology, 169(3), 356-367 (2015-01-24)

Adult T cell leukaemia/lymphoma (ATL) is a human T cell leukaemia virus type-I (HTLV-I)-infected T cell malignancy with poor prognosis. We herein developed a novel therapeutic vaccine designed to augment an HTLV-I Tax-specific cytotoxic T lymphocyte (CTL) response that has

A randomized controlled trial of single-class maintenance therapy with abacavir/lamivudine/zidovudine after standard triple antiretroviral induction therapy: final 96-week results from the FREE study.

H G Sprenger et al.

HIV medicine, 16(2), 122-131 (2014-12-05)

The aim of the study was to test the antiviral efficacy of a triple nucleoside reverse transcriptase inhibitor (NRTI) regimen, with potential beneficial metabolic effects, as maintenance therapy after induction with dual NRTIs and a boosted protease inhibitor (PI). An

Artemether-lumefantrine co-administration with antiretrovirals: population pharmacokinetics and dosing implications.

Richard M Hoglund et al.

British journal of clinical pharmacology, 79(4), 636-649 (2014-10-10)

Drug-drug interactions between antimalarial and antiretroviral drugs may influence antimalarial treatment outcomes. The aim of this study was to investigate the potential drug-drug interactions between the antimalarial drugs, lumefantrine, artemether and their respective metabolites desbutyl-lumefantrine and dihydroartemisinin, and the HIV

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全球贸易项目编号

货号	GTIN
1724500-400MG	04061838751553