Biology of reproduction, 67(5), 1439-1449 (2002-10-23)
Lactoferrin, an iron-binding glycoprotein, kills bacteria and modulates inflammatory and immune responses. Presence of lactoferrin in the female reproductive tract suggests that the protein may be part of the mucosal immune system and act as the first line of defense
Translational andrology and urology, 12(10), 1497-1510 (2023-11-16)
Infertility becomes a global problem that affects to the same extent females and males. As reasons of male infertility can differ among individuals, the accurate diagnostics is essential for effective treatment. The most problematic both in diagnostics and in treatment
The high plasticity of lung epithelial cells, has for many years, confounded the correct identification of the cell-of-origin of lung adenocarcinoma (LUAD), one of the deadliest malignancies worldwide. Here, we employ lineage-tracing mouse models to investigate the cell of origin of Eml4-Alk
Lactoferrin--a multifunctional protein with antimicrobial properties.
Lactoferrin (LF) is a multifunctional protein found in mammals, and it shows broad-spectrum antimicrobial activity. To improve the functional properties of specific probiotics in order to provide both the beneficial characteristics of lactic acid bacteria and the biological activity of
Molecular human reproduction, 8(1), 58-67 (2002-01-05)
We have previously shown that the estrogen responsiveness of the human lactoferrin gene in a transient transfection system is mediated through an imperfect estrogen response element (ERE) and a steroidogenic factor 1 binding element (SFRE) 26 bp upstream from ERE.
The Biochemical journal, 240(2), 413-422 (1986-12-01)
An oestrogen-induced secretory protein from mouse uterine luminal fluid was purified by CM-Affi-Gel Blue chromatography and reverse-phase h.p.l.c. This protein has an apparent molecular mass of approx. 70 kDa both by SDS/polyacrylamide-gel electrophoresis (with or without 2-mercaptoethanol) and by gel-filtration
Cells demonstrate plasticity following injury, but the extent of this phenomenon and the cellular mechanisms involved remain underexplored. Using single-cell RNA sequencing (scRNA-seq) and lineage tracing, we uncover that myoepithelial cells (MECs) of the submucosal glands (SMGs) proliferate and migrate
Lactoferrin gene expression and regulation: an overview.
Teng, Christina T
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 80, 7-16 (2002)
Growing evidence indicates that circulating lactoferrin (Lf) is implicated in peripheral cholesterol metabolism disorders. It has emerged that the distribution of Lf changes in astrocytes of aging brains and those exhibiting neurodegeneration; however, its physiological and/or pathological role remains unknown.
Quantification of the host response proteome after mammalian reovirus T1L infection.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 69(3) (2018-08-28)
Reduced sperm motility, defined as asthenozoospermia, is a frequent cause of male infertility, and is mainly connected with the dysfunction of sperm mitochondria. The aim of this study was to identify the proteins, and thereby the metabolic pathways, responsible for
Technology evaluation: rh lactoferrin, Agennix.
Andersen, Jeanette H
Current Opinion in Molecular Therapeutics, 6, 344-349 (2004)
Frontiers in immunology, 12, 749468-749468 (2021-10-19)
In the last few years, microbial infection and innate immune theories have been proposed as an alternative approach explaining the etiopathogenesis and origin of Alzheimer's disease (AD). Lactoferrin, one of the main antimicrobial proteins in saliva, is an important modulator
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Lactoferrin functions: current status and perspectives.
Valenti, Piera, et al.
Journal of Clinical Gastroenterology, 38, S127-S129 (2004)