09-143

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Co-opted genes of algal origin protect C. elegans against cyanogenic toxins.

Bingying Wang et al.

Current biology : CB, 32(22), 4941-4948 (2022-10-13)

Amygdalin is a cyanogenic glycoside enriched in the tissues of many edible plants, including seeds of stone fruits such as cherry (Prunus avium), peach (Prunus persica), and apple (Malus domestica). These plants biosynthesize amygdalin in defense against herbivore animals, as

Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

Monika Kasprzycka et al.

The American journal of pathology, 168(5), 1631-1641 (2006-05-03)

Tyrosine kinases play a fundamental role in cell proliferation, survival, adhesion, and motility and have also been shown to mediate malignant cell transformation. Here we describe constitutive expression of the protein tyrosine kinase Brk in a large proportion of cutaneous

Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition.

Haoqun Qiu et al.

The Journal of biological chemistry, 277(37), 34634-34641 (2002-07-18)

Brk (breast tumor kinase) is a nonreceptor tyrosine kinase that is most closely related to the Frk family of kinases, and more distantly to Src family kinases. Brk was originally identified in a screen for tyrosine kinases that are overexpressed

Interaction between Brk kinase and insulin receptor substrate-4.

Haoqun Qiu et al.

Oncogene, 24(36), 5656-5664 (2005-05-05)

Breast tumor kinase (Brk) is a member of the Frk family of nonreceptor tyrosine kinases that is overexpressed in a high percentage of human breast tumors. The downstream substrates and effectors of Brk remain largely unidentified. In this study, we

Growth response of Escherichia coli ATCC 35218 adapted to several concentrations of sodium benzoate and potassium sorbate.

Santiesteban-Lopez NA, Rosales M, Palou E, Lopez-Malo A

Journal of Food Protection null

The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis.

Andrea Haegebarth et al.

Cell cycle (Georgetown, Tex.), 4(9), 1239-1246 (2005-08-06)

The intracellular tyrosine kinase Brk is expressed in regenerating epithelial tissues with highest levels in the gastrointestinal tract and skin. In these tissues, Brk is restricted to epithelial cells that are exiting the cell cycle and undergoing terminal differentiation. While

Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC).

Sarah C Bath et al.

Lancet (London, England), 382(9889), 331-337 (2013-05-28)

As a component of thyroid hormones, iodine is essential for fetal brain development. Although the UK has long been considered iodine replete, increasing evidence suggests that it might now be mildly iodine deficient. We assessed whether mild iodine deficiency during

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