09143

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Discovery of estrogen receptor α modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells.

Li Liu et al.

Bioorganic & medicinal chemistry letters, 22(1), 154-163 (2011-12-06)

The binding between the estrogen receptor α (ER-α) and a variety of compounds in traditional Chinese formulae, Si-Wu-Tang (SWT) series decoctions, was studied using a stably-transfected human breast cancer cell line (MVLN). In 38 compounds tested from SWT series decoctions

Final report on the safety assessment of benzaldehyde.

Alan Andersen

International journal of toxicology, 25 Suppl 1, 11-27 (2006-07-13)

Benzaldehyde is an aromatic aldehyde used in cosmetics as a denaturant, a flavoring agent, and as a fragrance. Currently used in only seven cosmetic products, its highest reported concentration of use was 0.5% in perfumes. Benzaldehyde is a generally regarded

Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.

Minna Rahnasto et al.

Journal of medicinal chemistry, 48(2), 440-449 (2005-01-22)

The purpose of this study was to develop screening and in silico modeling methods to obtain accurate information on the active center of CYP2A6, a nicotine oxidizing enzyme. The inhibitory potencies of 26 naphthalene and 16 non-naphthalene derivatives were determined

Capillary gas chromatography determination of benzaldehyde arising from benzyl alcohol used as preservative in injectable formulations.

Kazemifard AG, et al.

Journal of Pharmaceutical and Biomedical Analysis, 31(4), 685-691 (2003)

New Cu(I)-ethylene complexes based on tridentate imine ligands: synthesis and structure.

Parisa Ebrahimpour et al.

Inorganic chemistry, 52(7), 3765-3771 (2013-03-19)

A new bulky facially coordinating N3-donor tach-based ligand (tach: cis,cis-1,3,5-triaminocyclohexane) [1: cis,cis-1,3,5-tris(2-fluoro-6-(trifluoromethyl)benzylideneamino)cyclohexane] has been obtained from the condensation of tach with 3 equiv of the appropriate benzaldehyde. Reaction of 1 with [Cu(NCMe)4][PF6] gave the complex [(1)Cu(NCMe)][PF6]. Displacement of the acetonitrile

Templating effect in DNA proximity ligation enables use of non-bioorthogonal chemistry in biological fluids.

Nicholas G Spiropulos et al.

Artificial DNA, PNA & XNA, 3(3), 123-128 (2013-02-02)

Here we describe the first example of selective reductive amination in biological fluids using split aptamer proximity ligation (StAPL). Utilizing the cocaine split aptamer, we demonstrate small-molecule-dependent ligation that is dose-dependent over a wide range of target concentrations in buffer

Proton transfer reactions between nitric acid and acetone, hydroxyacetone, acetaldehyde and benzaldehyde in the solid phase.

Jérôme Lasne et al.

Physical chemistry chemical physics : PCCP, 14(45), 15715-15721 (2012-10-24)

The heterogeneous and homogeneous reactions of acetone, hydroxyacetone, acetaldehyde and benzaldehyde with solid nitric acid (HNO(3)) films have been studied with Reflection-Absorption Infrared Spectroscopy (RAIRS) under Ultra-High Vacuum (UHV) conditions in the 90-170 K temperature range. In the bulk or

Headspace solid-phase microextraction gas chromatography-mass spectrometry and gas chromatography-olfactometry analysis of volatile compounds in pineapple breads.

Saw Ying et al.

Molecules (Basel, Switzerland), 17(12), 13795-13812 (2012-11-24)

Sensorial analysis of pineapple breads (conventionally baked, Cpb; fully baked frozen, Fpb and partially baked, Ppb) showed no significant differences in terms of aroma and taste. On the contrary, the scores for the overall quality between the partially baked and

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