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A Fuchisawa et al.
Immunohematology, 25(1), 18-19 (2009-10-28)
The Scianna blood group system comprises seven antigens encoded by alternative forms of SC. The SC gene also has two polymorphisms in the leader sequence, at nucleotides 54 (C/T, silent) and 76 (C/T, 26His/Tyr) in exon 2, which are not
Bert Tuk et al.
Journal of pharmacokinetics and pharmacodynamics, 29(3), 235-250 (2002-11-27)
The pharmacokinetic and pharmacodynamic interactions of ethanol with the full benzodiazepine agonist midazolam, the partial agonist bretazenil and the benzodiazepine BZ1 receptor subtype selective agonist zolpidem have been determined in the rat in vivo, using an integrated pharmacokinetic-pharmacodynamic approach. Ethanol
Lori J Day et al.
Reproductive sciences (Thousand Oaks, Calif.), 18(3), 286-295 (2011-01-27)
The objectives were to determine whether single-nucleotide polymorphisms (SNPs) in KCNN3 (encodes the small conductance calcium-activated potassium channel subfamily N, member 3), associate with preterm birth (PTB). In all, 602 preterm families with at least 1 preterm (<37 weeks gestation)
Reyhan Polat et al.
Middle East journal of anaesthesiology, 21(5), 673-677 (2012-12-26)
Propofol injection pain is a frequent and a well-known complaint distressing for the patients. Although the ethiology of this pain remains obscure, the ideal method for the prevention of propofol injection pain is still controversial. Local anesthetics, opioids, nonsteroidal anti-inflammatory
Pavel L Volodin et al.
Ophthalmic surgery, lasers & imaging retina, 51(9), 512-520 (2020-09-22)
A computational model has predicted parameters for using a navigated microsecond pulsing laser system to treat central serous chorioretinopathy (CSC). A prospective, single-center, interventional case series was conducted for patients with acute CSC who were enrolled following screening and informed
R Ermirio et al.
Neuroscience letters, 104(1-2), 115-120 (1989-09-25)
The effects of microinjections of 3 alpha,5 alpha-tetrahydrodeoxycorticosterone (3 alpha-THDOC) on single neurones of the mesencephalic reticular formation (MRF) were investigated in rats anaesthetized with urethan. Microinjections of approximately 100 nl of 0.5-2 microM 3 alpha-THDOC inhibited firing of 105
Marissa D Newman et al.
Cutis, 88(5), 256-259 (2012-01-26)
Vitiligo vulgaris is an autoimmune pigmentary disorder with no universally efficacious therapeutic options. Separate applications of calcipotriene ointment 0.005% and topical corticosteroid ointments have been successful in the repigmentation of vitiligo. We sought to examine the efficacy of a combination
J Pang et al.
Die Pharmazie, 74(2), 79-82 (2019-02-21)
IG-105, N-(2, 6-dimethoxypyridine-3-yl)-9-methylcarbazole-3-sulfonamide, a novel carbazole sulfonamide, shows a potent anticancer activity in a variety of human tumor cells in vitro and in vivo. In the present study, a rapid and convenient liquid chromatography/tandem mass spectrometry (LC-MS/MS) method was developed
Karen M Chisholm et al.
Applied immunohistochemistry & molecular morphology : AIMM, 24(9), 627-632 (2016-10-18)
Hirschsprung disease (HD) is a congenital malformation resulting from the lack of migration of ganglion cells in the colon. The absence of ganglion cells in rectal suction biopsies aids in diagnosis, but evaluation of these small biopsies can be difficult.
Laëtitia Duché et al.
BMC pediatrics, 8, 29-29 (2008-07-18)
Numerous short-statured children are evaluated for growth hormone (GH) deficiency (GHD). In most patients, GH provocative tests are normal and are thus in retrospect unnecessary. A retrospective cohort study was conducted to identify predictors of growth hormone (GH) deficiency (GHD)
Jian Shi et al.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 27(4), 515-517 (2007-06-05)
To investigate the association between p16, p53 and Ki-67 expression and high-risk human papilloma virus (HPV) infection in cervical intraepithelial neoplasia (CIN). Using a self-prepared tissue microarray, p16, p53, and Ki-67 expression was detected in 243 cases of CIN and
C Flummer et al.
Journal of animal science, 90 Suppl 4, 372-374 (2013-02-13)
This trial was conducted to investigate whether β-hydroxy β-methyl butyrate (HMB) supplementation during late gestation and throughout lactation would influence colostrum and milk production of sows and neonatal piglet survival (0 to 24 h). Control sows (CON; n = 8)
V I Kulinskiĭ et al.
Radiatsionnaia biologiia, radioecologiia, 37(6), 914-917 (1998-02-19)
Experiments are carried out on 3400 mice, irradiated in dose 8 Gy (LD97/30). beta-Ketoanalogs of adrenaline (adrenalone, 50-150 mumol/kg), m,p-dipivaloyladrenaline (20 mumol/kg) and phenylephrine (but at 2070 mumol/kg) have the high radioprotective effect (survival is 60-100%), beta-ketoanalogs of isoprenaline and
Marta Goretti et al.
International journal of food microbiology, 131(2-3), 178-182 (2009-03-10)
The in vitro antimycotic activity of a purified killer protein (KT4561) secreted by a strain of Williopsis saturnus was tested against 310 yeast strains belonging to 21 food spoilage species of 14 genera (Candida, Debaryomyces, Dekkera, Hanseniaspora, Issatchenkia, Kazachstania, Kluyveromyces
J Y Tso et al.
Nucleic acids research, 13(7), 2485-2502 (1985-04-11)
Full length cDNAs encoding the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from rat and man have been isolated and sequenced. Many GAPDH gene-related sequences have been found in both genomes based on genomic blot hybridization analysis. Only one functional gene product
Ho To et al.
The Journal of veterinary medical science, 74(7), 949-953 (2012-03-27)
The objective of the present study was to characterize Erysipelothrix sp. strains from recent erysipelas outbreaks in Japan. Eighty-three (100%) strains were identified as E. rhusiopathiae, based on serotyping and spaA PCR. Fifty (60.3%), 5 (6.0%), and 28 (33.7%) strains
Raphaël Lepeule et al.
Antimicrobial agents and chemotherapy, 56(3), 1376-1381 (2012-01-05)
We investigated the efficiency of the cephamycin cefoxitin as an alternative to carbapenems for the treatment of urinary tract infections (UTIs) due to Escherichia coli producing CTX-M-type extended-spectrum β-lactamases. The susceptible, UTI-inducing E. coli CFT073-RR strain and its transconjugant CFT073-RR
Doron Bushi et al.
Journal of neuroscience research, 96(8), 1406-1411 (2018-05-16)
Factor Xa (FXa) plays a critical role in the coagulation cascade by generation of thrombin. During focal ischemia thrombin levels increase in the brain tissue and cause neural damage. This study examined the hypothesis that administration of the FXa inhibitor
Kaori Sayanagi et al.
The British journal of ophthalmology, 99(1), 29-35 (2014-08-12)
To observe the choroidal microstructure in polypoidal choroidal vasculopathy (PCV) using high-penetration optical coherence tomography (HP-OCT) with a long-wavelength light source that visualises tissue beneath the retinal pigment epithelium (RPE) and deep choroid, and to compare the findings with those
Bao-hua Yu et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 38(1), 35-41 (2009-06-06)
(1) To investigate the activation of AKT/mTOR signaling transduction pathway in DLBCL and its association with the expression of bcl-6 and some other clinical pathologic factors. (2) To estimation of the signaling pathway function in diverse subtypes of DLBCL and
G A Pankey
Clinical pharmacokinetics, 16 Suppl 1, 46-51 (1989-01-01)
Enoxacin achieves a high penetration into skin tissue and blister fluid, reaching a maximum serum concentration (Cmax) of 3.7 mg/L at a time to reach maximum concentration (tmax) of 1.9 hours and a blister-fluid Cmax of 2.9 mg/L at a
Qiaozhen Guo et al.
Journal of separation science, 36(4), 677-683 (2013-01-24)
Simultaneous determination of bisphenol A, tetrabromobisphenol A, and perfluorooctanoic acid in small household electronics appliances by accelerated solvent extraction-ultra-performance liquid chromatography-tandem mass spectrometry was established. Samples, heated for 5 min, were extracted by toluene/methanol (10:1, v/v) under the pressure 1500
Ayhan Ozcan et al.
Archives of pathology & laboratory medicine, 136(12), 1541-1551 (2012-12-01)
The diagnosis of renal cell carcinoma (RCC) remains problematic, especially in the context of metastasis or small-needle biopsies. PAX2 and PAX8 transcription factors are known to be expressed by several histologic types of renal neoplasms. To evaluate the diagnostic utility
Mayara L Serejo et al.
Environmental science & technology, 49(5), 3228-3236 (2015-02-13)
The influence of biogas flow rate (0, 0.3, 0.6, and 1.2 m(3) m(-2) h(-1)) on the elemental and macromolecular composition of the algal-bacterial biomass produced from biogas upgrading in a 180 L photobioreactor interconnected to a 2.5 L external bubbled
Kyoko Nakagawa-Goto et al.
Bioorganic & medicinal chemistry letters, 19(13), 3378-3381 (2009-06-02)
C-3 esterifications of betulinic acid (BA, 1) and its A-ring homolog, ceanothic acid (CA, 2), were carried out to provide sixteen terpenoids, 4-19, including nine new compounds (4-12). All synthesized compounds were evaluated in an in vitro antitumor-promoting assay using
Peter A Calabresi et al.
The Lancet. Neurology, 13(7), 657-665 (2014-05-06)
Subcutaneous pegylated interferon (peginterferon) beta-1a is being developed for treatment of relapsing multiple sclerosis, with less frequent dosing than currently available first-line injectable treatments. We assessed the safety and efficacy of peginterferon beta-1a after 48 weeks of treatment in the
R Flemming et al.
British journal of pharmacology, 139(5), 955-965 (2003-07-04)
1. In this study, we determined a pharmacological profile of store-operated channels (SOCs) in smooth muscle cells of rabbit pial arterioles. Ca(2+)-indicator dyes, fura-PE3 or fluo-4, were used to track [Ca(2+)](i) and 10 micro M methoxyverapamil (D600) was present in
A A Izzo et al.
Neuroscience, 91(4), 1575-1580 (1999-07-03)
The effect of muscarinic cholinoceptor antagonists was investigated on the ascending neural pathways activated by electrical stimulation in the guinea-pig ileum. For comparison, prejunctional and postjunctional effects of muscarinic cholinoceptor antagonists were also studied on circular smooth muscle. A two-compartment
Enriqueta Martinez-Rojas et al.
Chirality, 28(9), 623-627 (2016-08-09)
In the current study, we present a green toolbox to produce ecological compounds like lactone moiety. Rhodococcus erythropolis DSM 44534 cells have been used to oxidize both decane-1,4-diol () and decane-1,5-diol () into the corresponding γ- () and δ-decalactones ()
Kiranpreet K Khurana et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 64(3), 367-374 (2014-04-15)
Hypogonadism in men (total testosterone <350 ng/dL) is associated with higher risk of cardiovascular disease and mortality in men on dialysis therapy. We evaluated the association of hypogonadism with all-cause mortality in men with non-dialysis-dependent chronic kidney disease (CKD). Retrospective
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