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显示 1-26 共 26 条结果 关于 "101-32-6" 范围 论文
R Hui et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 28(4), 874-881 (2017-02-09)
Pembrolizumab improved survival as first- and second-line therapy compared with chemotherapy in patients with highly programmed death ligand 1 (PD-L1) expressing advanced non-small cell lung cancer (NSCLC). We report the long-term safety and clinical activity of pembrolizumab as first-line therapy
P Poorkaj et al.
Archives of neurology, 58(3), 383-387 (2001-03-20)
Mutations in the tau gene have been reported in families with frontotemporal dementia (FTD) linked to chromosome 17. It remains uncertain how commonly such mutations are found in patients with FTD or non-Alzheimer dementia with or without a positive family
Daniela Accorsi-Mendonça et al.
Journal of neurophysiology, 121(5), 1822-1830 (2019-03-21)
Sustained hypoxia (SH) activates chemoreceptors to produce cardiovascular and respiratory responses to bring the arterial partial pressure of O2 back to the physiological range. We evaluated the effect of SH (fraction of inspired O2 = 0.10, 24 h) on glutamatergic synaptic transmission
Jay P McLaughlin et al.
The Journal of biological chemistry, 279(3), 1810-1818 (2003-11-05)
Kappa opioid receptor (KOR) desensitization was previously shown to follow agonist-dependent phosphorylation of serine 369 by G-protein receptor kinase (GRK) and beta-arrestin binding in transfected cells. To study the in vivo effects induced by phosphorylation of KOR(S369), C57Bl/6 mice were
Jie Xie et al.
Journal of hazardous materials, 231-232, 57-63 (2012-07-10)
The aim of this study was to examine the adsorption capability and mechanism of hexadecyltrimethylammonium modified zeolite, which was synthesized from coal fly ash, for the removal of ionizable phenolic compounds (phenol, p-chlorophenol and bisphenol A, with different pK(a)) and
H Lu et al.
Journal of chromatography. B, Biomedical applications, 678(2), 219-225 (1996-04-12)
A sensitive and specific method for the quantitative analysis of N-2-chloroethylaziridine (CEA), a volatile cytotoxic metabolite of cyclophosphamide, has been developed using gas chromatography-mass spectrometry and stable isotope dilution techniques. The high volatility problem of CEA during isolation procedure was
Hannu Paajanen et al.
International journal of surgery (London, England), 11(1), 81-84 (2012-12-19)
Chronic pain may be a major long-term problem related to mesh material and operative trauma in inguinal hernioplasty. Lichtenstein hernioplasty was performed under local anaesthesia in 312 patients by the same surgeon and technique between 2003 and 2005. The patients
E J Schaefer et al.
Journal of lipid research, 36(7), 1427-1433 (1995-07-01)
In order to test the hypothesis that retinitis pigmentosa (RP) is associated with fatty acid abnormalities within cell membrane phospholipids, red blood cell membrane (RBC) phosphatidylethanolamine (PE) fatty acid content (% of total fatty acids) was measured using high performance
Jingzhong Ding et al.
American heart journal, 152(6), 1109-1115 (2006-12-13)
The 4G allele in the promoter region of the plasminogen activator inhibitor type 1 (PAI-1) gene is associated with higher plasma PAI-1 levels and activity, but its association with cardiovascular diseases is unclear. We investigated the association of polymorphisms and
Riichiroh Maruyama et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 8(2), 514-519 (2002-02-13)
We investigated the aberrant methylation profile of prostate cancers and correlated the data with clinical findings. Gene promoter methylation was analyzed in 101 prostate cancer samples. In addition, we analyzed 32 nonmalignant prostate tissue samples, which included 25 with benign
Takuma Hayashi et al.
North American journal of medical sciences, 3(9), 394-399 (2012-03-01)
Although the majority of smooth muscle neoplasms found in the uterus are benign, uterine leiomyosarcoma is extremely malignant, with high rates of recurrence and metastasis. The development of gynecologic tumors is often correlated with secretion of female hormone; however, the
Y Asayama et al.
Clinical radiology, 71(12), 1277-1283 (2016-05-24)
To clarify the frequency of fatty change in moderately and poorly differentiated hepatocellular carcinomas (mHCCs and pHCCs) and its relationship to arterial blood flow. One hundred and thirty-six surgically resected HCC lesions were studied. All patients had undergone dynamic magnetic
Asha Padar et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 9(13), 4730-4734 (2003-10-29)
Loss or abnormal expression of Cyclin D2, a crucial cell cycle-regulatory gene, has been described in human cancers; however, data for prostate tumors are lacking. We investigated the epigenetic silencing of Cyclin D2 gene in prostate cancers and correlated the
R Schwab et al.
Hernia : the journal of hernias and abdominal wall surgery, 8(3), 226-232 (2004-03-26)
Endoscopic techniques are commonly used for many different types of surgery. It is claimed that videoendoscopic procedures have the advantage of being less traumatic and of offering higher postoperative patient comfort than conventional open techniques. The extent of tissue trauma
Sara S Jarvis et al.
Frontiers in physiology, 5, 86-86 (2014-03-14)
Young black women have higher prevalence of hypertension during pregnancy compared to white women, which may be attributable to differences in blood pressure (BP) regulation. We hypothesized that young normotensive black women would demonstrate augmented muscle sympathetic nerve activity (MSNA)
Eric Grondin et al.
International journal of food microbiology, 203, 101-108 (2015-03-25)
In recent years, there has been an increasing interest in identifying and characterizing the yeast flora associated with diverse types of habitat because of the many potential desirable technological properties of these microorganisms, especially in food applications. In this study
Y Gorgi et al.
Transplantation proceedings, 41(2), 660-662 (2009-03-31)
Mannose-binding lectin (MBL), a collagen-like serum protein, is a key component of innate immunity. MBL binding to carbohydrates present on pathogens mediates lectin-dependent activation of the complement pathway. There is growing interest in the importance of innate immunity in host
Anna M Varghese et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 8(1), 123-125 (2012-12-18)
We hypothesize that among patients with lung cancers the KRAS/EGFR mutation profile and overall survival of collegiate smokers (former smokers who smoked between 101 lifetime cigarettes and 5 pack-years) are distinct from those of never smokers and former smokers with
Simone Mader et al.
Journal of neuroinflammation, 8, 184-184 (2011-12-30)
Serum autoantibodies against the water channel aquaporin-4 (AQP4) are important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO). However, AQP4-IgG are absent in 5-40% of all NMO patients and the target of the autoimmune response in these patients is
Rakesh Rao et al.
Pediatric research, 65(5), 548-552 (2009-02-05)
Neurotrophins (NTs) play important roles in brain growth and development. Cord blood (CB) brain-derived neurotrophic factor (BDNF) concentrations increase with gestational age but data regarding postnatal changes are limited. We measured BDNF concentrations after birth in 33 preterm infants <32-wk
V R Antunes et al.
The Journal of physiology, 576(Pt 2), 569-583 (2006-07-29)
An elevation in plasma osmolality elicits a complex neurohumoral response, including an activation of the sympathetic nervous system and an increase in arterial pressure. Using a combination of in vivo and in situ rat preparations, we sought to investigate whether
Ming-Sheng Zhou et al.
American journal of physiology. Heart and circulatory physiology, 296(3), H833-H839 (2009-01-20)
Insulin activation of the phosphatidylinositol 3-kinase (PI3K) pathway stimulates glucose uptake in peripheral tissues and synthesis of nitric oxide (NO) in the endothelium. Insulin resistance (IR) and hypertension frequently coexist, particularly among individuals with salt-sensitive hypertension. The mechanisms underlying this
Ase M Hansen et al.
International journal of hygiene and environmental health, 211(5-6), 471-503 (2008-01-29)
A total of 132 studies were identified, of which 25 studies addressed environmental exposure to polycyclic aromatic hydrocarbons (PAHs) in the general population. Of these 9 studies included children. Of 101 studies among workers in various occupations, 32 studies were
Jason L Hornick et al.
The American journal of surgical pathology, 27(9), 1183-1196 (2003-09-10)
Myoepitheliomas and mixed tumors were only recently recognized to occur primarily in soft tissue, and only small case numbers have been described. To characterize these tumors further and to evaluate prognostic parameters, 101 myoepithelial tumors of soft tissue were retrieved
D Adam Algren et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 9(1), 106-115 (2013-01-30)
During the summer of 2005, multiple cities in the United States began to report outbreaks of fentanyl-associated fatalities among illicit drug users. The objectives of this study were to (1) determine if an outbreak of fentanyl-associated fatalities occurred in mid-2005
Ihab Hajjar et al.
JAMA network open, 3(8), e2012252-e2012252 (2020-08-08)
Observational studies have suggested that angiotensin receptor blockers are associated with a unique cognitive protection. It is unclear if this is due to reduced blood pressure (BP) or angiotensin receptors type 1 blockade. To determine neurocognitive effects of candesartan vs
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