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关键词:'101-37-1'
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Karel Allegaert et al.
BMC anesthesiology, 15, 163-163 (2015-11-17)
There is relevant between individual variability in paracetamol clearance in young women. In this pooled study, we focused on the population pharmacokinetic profile of intravenous paracetamol metabolism and its covariates in young women. Population PK parameters using non-linear mixed effect
Johnston et al.
The Journal of experimental biology, 201 (Pt 12), 623-646 (1998-02-06)
The influence of embryonic and larval temperature regime on muscle growth was investigated in Atlantic herring (Clupea harengus L.). Eggs of spring-spawning Clyde herring were incubated at 5 degrees C, 8 degrees C or 12 degrees C until hatching and
Tomas Lenz et al.
Kidney & blood pressure research, 26(5-6), 338-343 (2003-11-12)
Vascular endothelial growth factor (VEGF) increases endothelial permeability. VEGF is produced in podocytes and functional receptors are located on endothelial glomerular cells. The aim of the current study in diabetic patients with normal renal function to various degrees of proteinuric
Martin Alberer et al.
Lancet (London, England), 390(10101), 1511-1520 (2017-07-30)
Vaccines based on mRNA coding for antigens have been shown to be safe and immunogenic in preclinical models. We aimed to report results of the first-in-human proof-of-concept clinical trial in healthy adults of a prophylactic mRNA-based vaccine encoding rabies virus
A Weise et al.
Clinical laboratory, 56(7-8), 311-318 (2010-09-23)
Drug degradation in the human organism is driven by detoxification mechanisms that can be affected in their efficiency by genetic mutations. The purpose of this pilot investigation was to investigate whether Type 2 diabetes is associated with mutations in prominent
Jan Borys et al.
Frontiers in physiology, 8, 386-386 (2017-06-24)
Titanium miniplates and screws are commonly used for fixation of jaw fractured or osteotomies. Despite the opinion of their biocompatibility, in clinical practice symptoms of chronic inflammation around the fixation develop in some patients, even many years after the application
Charis Costopoulos et al.
JACC. Cardiovascular imaging, 10(12), 1472-1483 (2017-07-25)
The aim of this study was to identify the determinants of plaque structural stress (PSS) and the relationship between PSS and plaques with rupture. Plaque rupture is the most common cause of myocardial infarction, occurring particularly in higher risk lesions
Aleksandra Norek et al.
Medycyna wieku rozwojowego, 14(4), 334-343 (2011-04-06)
Verification of the hypothesis concerning the association between polymorphic variants of the following genes: COLIA1, VDR and CALCR considered to be risk factors of bone metabolism disturbances and decreased bone mineral density (BMD) in children with cystic fibrosis (CF). Clinical
I N Ruchkina et al.
Terapevticheskii arkhiv, 85(2), 21-26 (2013-05-09)
To estimate the incidence of secondary lactase deficiency (SLD) in patients with postinfectious irritable bowel syndrome (PIBS) and the value of the small bowel microflora in its development and to elaborate treatment options for SLD. One hundred and thirty-eight patients
Thack T Lang et al.
Molecular pharmacology, 65(4), 925-933 (2004-03-27)
Pharmacologically important drugs were examined as potential inhibitors or permeants of human concentrative nucleoside transporters 1 (hCNT1)- and 2 (hCNT2)-producing stable transfectants by assessing their abilities to inhibit uridine transport. hCNT1 exhibited high affinities for uridine analogs (5-fluorouridine, 2'-deoxyuridine, 5-fluoro-2'-deoxyuridine
Yunxia O'Malley et al.
Journal of applied physiology (Bethesda, Md. : 1985), 125(1), 97-106 (2018-03-09)
Pancreatic ductular epithelial cells comprise the majority of duct cells in pancreas, control cystic fibrosis transmembrane conductance regulator (CFTR)-dependent bicarbonate ([Formula: see text]) secretion, but are difficult to grow as a polarized monolayer. Using NIH-3T3-J2 fibroblast feeder cells and a
E L Cuttance et al.
New Zealand veterinary journal, 63(5), 276-283 (2015-04-03)
To determine some of the risk factors for cows not observed in oestrus within 35-42 days of an unsuccessful artificial insemination (AI; phantom cows), and the reproductive outcomes and effect of treatment of phantom cows. Over 2 years, in dairy
D Adam Algren et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 9(1), 106-115 (2013-01-30)
During the summer of 2005, multiple cities in the United States began to report outbreaks of fentanyl-associated fatalities among illicit drug users. The objectives of this study were to (1) determine if an outbreak of fentanyl-associated fatalities occurred in mid-2005
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