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Xieer Liang et al.
Journal of gastroenterology and hepatology, 30(4), 748-755 (2014-10-30)
Data about the efficacy of de novo combination therapies, or optimization strategy by adding the other drug based on the virological response at week 24 of low genetic barrier antiviral agents is still limited. This study aimed to compare the
Natalie Ebert et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 30(8), 1307-1314 (2015-06-06)
Accurate and precise measurement of GFR is important for patients with chronic kidney disease (CKD). Sampling time of exogenous filtration markers may have great impact on measured GFR (mGFR) results, but there is still uncertainty about optimal timing of plasma
M Ueda et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 17(4), 794-797 (2007-02-21)
It has been shown that ovarian low-grade serous carcinoma evolves out of a stepwise progression from benign serous cystadenoma to serous borderline tumor (SBT) to micropapillary serous carcinoma (MPSC), and that BRAF activation is a very early somatic event in
Tetsuya Nakatsura et al.
European journal of immunology, 32(3), 826-836 (2002-03-01)
Among a number of human tumor antigens identified using the serological analysis of recombinant cDNA expression libraries (SEREX), only MAGE-1, tyrosinase, and NY-ESO-1 have been reported to be immunogenic tumor antigens that have the potential to elicit both humoral and
Jeffrey B Raskin et al.
Gastroenterology, 147(4), 793-802 (2014-07-20)
No therapy has been proven to prevent the recurrence of diverticulitis. Mesalamine has shown efficacy in preventing relapse in inflammatory bowel disease, and there is preliminary evidence that it might be effective for diverticular disease. We investigated the efficacy of
Carla Filì et al.
Leukemia research, 76, 33-38 (2018-12-12)
The hypomethylating agent Decitabine (DAC) is a valuable treatment option in acute myeloid leukemia (AML), particularly in elderly patients (pts) not suitable for intensive chemotherapy (CHT). However, limited data are available about efficacy and safety of DAC in clinical practice.
Martina Felici et al.
Poultry science, 99(11), 5350-5355 (2020-11-05)
The anticoccidial activity of thymol, carvacrol, and saponins was assessed in an in vitro model of coccidiosis. Eimeria spp. sporozoites were collected from field samples, characterized, and used for 2 different invasion assays on Madin-Darby Bovine Kidney cells (MDBK). The cells
Taisa Nogueira Pansani et al.
Archives of oral biology, 102, 48-54 (2019-04-10)
Different strategies, such as modifications on the implant abutments surface have been proposed to accelerate and improve the formation of the biological seal (BS). The aim of this study was to characterize a titanium (Ti) surface impregnated with epidermal growth
Michael D Edstein et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 37(12), 1654-1658 (2003-12-23)
We measured plasma tafenoquine concentrations in Thai soldiers given a monthly regimen of tafenoquine to determine whether these concentrations adequately suppressed malarial infections on the Thai-Cambodian border. After receiving a treatment course of artesunate and doxycycline, 104 male soldiers were
Camille Lassale et al.
The British journal of nutrition, 113(6), 953-962 (2015-03-17)
New technologies are promising for the use of short-term instruments for dietary data collection; however, innovative tools should be validated against objective biomarkers. The aim of the present study was to investigate the validity of a Web-based, self-administered dietary record
W Kamphuis et al.
Molecular vision, 13, 1020-1030 (2007-07-27)
To obtain and analyze the gene expression changes after ischemic preconditioning (IPC) in the rat retina. Ischemic damage to the inner retina can be prevented by a short, non-deleterious, ischemic insult of 5 min applied 24 h preceding a full
D J Diamond et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(5), 1615-1619 (1988-03-01)
Genomic DNA clones containing the human and murine genes coding for the 50-kDa T11 (CD2) T-cell surface glycoprotein were characterized. The human T11 gene is approximately equal to 12 kilobases long and comprised of five exons. A leader exon (L)
Yoshio Matsui et al.
Hypertension (Dallas, Tex. : 1979), 59(6), 1132-1138 (2012-05-02)
Day-by-day home blood pressure (BP) variability (BPV) was reported to be associated with increased cardiovascular risk. We aimed to test the hypothesis that the angiotensin II receptor blocker/calcium-channel blocker combination decreases day-by-day BPV more than the angiotensin II receptor blocker/diuretic
M Watanabe et al.
American journal of human genetics, 58(2), 308-316 (1996-02-01)
Individuals with 50% of expected triosephosphate isomerase (TPI) enzyme activity have been previously identified in families during the screening of approximately 2,000 newborn children for quantitative variation in activity of 12 erythrocyte enzymes. The frequency of the trait was 9/1,713
C E Fardella et al.
The Journal of clinical endocrinology and metabolism, 81(12), 4347-4351 (1996-12-01)
Low renin hypertension (LRH), which accounts for 10-20% of patients with idiopathic "essential" hypertension, bears hormonal similarities to mineralocorticoid-induced hypertension, but elevated mineralocorticoid concentrations have not been found. Some patients with LRH have normal, rather than suppressed, plasma aldosterone concentrations
Hendrik Busse et al.
Cardiovascular drugs and therapy, 30(6), 551-558 (2016-10-21)
Mechanical and morphological ischemia and reperfusion (I/R) injury is reduced in septic hearts. The mechanism behind this "cardioprotection" is less well understood. As adenosine receptors play a major role for cardioprotection in non-septic hearts, we investigated the influence of adenosine
Ladin Yurteri-Kaplan et al.
Reproductive sciences (Thousand Oaks, Calif.), 19(5), 520-525 (2012-05-02)
To determine the normal range of serum brain natriuretic peptide (BNP) in uncomplicated, singleton term pregnant patients. Serum for analysis of BNP was drawn at admission to labor and delivery (= 104), prior to administration of intravenous fluid. Median BNP
Zoë L S Brookes et al.
The Journal of physiology, 565(Pt 1), 269-277 (2005-02-19)
We developed a novel model using fluorescent intravital microscopy to study the effect of atrial natriuretic peptide (ANP) on the extrasplenic microcirculation. Continuous infusion of ANP into the splenic artery (10 ng min(-1) for 60 min) of male Long-Evans rats
C Sánchez et al.
Cellular and molecular neurobiology, 19(4), 467-489 (1999-06-24)
1. The present survey compares the effects of antidepressants and their principal metabolites on reuptake of biogenic amines and on receptor binding. The following antide-pressants were included in the study: the tricyclic antidepressants amitriptyline, dothiepin, and lofepramine and the atypical
Wenjing Wang et al.
Poultry science, 99(1), 89-94 (2020-05-18)
The study was conducted to develop a specific, simple, and sensitive method for diagnosis of avian infectious bronchitis virus (IBV). In this experiment, the selected downstream primer was labeled with biotin and the 5' end of RAA probe was labeled
Frank Seibold et al.
Inflammatory bowel diseases, 13(9), 1077-1082 (2007-05-08)
Antibodies against mannan, a component of the yeast Saccharomyces cerevisiae cell wall, are more frequently found in Crohn's disease (CD) patients with low levels of mannan-binding lectin (MBL). MBL concentration depends on genetic polymorphisms. The aim of this study was
A Rosen et al.
International immunology, 7(4), 625-633 (1995-04-01)
In this study, a B cell growth stimulatory factor, constitutively secreted by a human CD4+ T cell hybridoma clone, MP6, has been purified and characterized. Serum-free 24 h culture media from MP6 cells were collected, concentrated by ultrafiltration and separated
C Liniger et al.
The Journal of endocrinology, 112(1), 171-175 (1987-01-01)
SR-202 is a non-iodinated potential lipid-altering agent. When administered (100 mg) three times per day for 3 days to six euthyroid subjects it was associated with a 30 +/- 3% (mean +/- S.E.M.) fall in 3,3',5-triiodothyronine (T3) (P less than
Robert S Kellar et al.
Journal of cardiovascular pharmacology, 57(5), 568-574 (2011-02-18)
Granulocyte macrophage colony-stimulating factor (GM-CSF) promotes infarct expansion and inappropriate collagen synthesis in a myocardial infarction (MI). This study was designed to determine if treatment with anti-GM-CSF will inhibit macrophage migration, preserve function, and limit left ventricular (LV) remodeling in
Craig R Lee et al.
Pharmacogenetics and genomics, 17(2), 145-160 (2007-02-16)
Cyclooxygenase-1 (COX-1, PTGS1) catalyzes the conversion of arachidonic acid to prostaglandin H2, which is subsequently metabolized to various biologically active prostaglandins. We sought to identify and characterize the functional relevance of genetic polymorphisms in PTGS1. Sequence variations in human PTGS1
Dan Zhao et al.
Zhonghua fu chan ke za zhi, 44(2), 87-90 (2009-07-03)
To explore the role of H19 imprinting in etiology of pre-eclampsia. Placentas of 24 women with pre-eclampsia (3 with mild pre-eclampsia and 21 with severe pre-eclampsia) and 50 healthy pregnant women at full term (control) were collected during selected cesarean
Agostino Pugliese et al.
European cytokine network, 16(3), 186-190 (2005-11-04)
Interleukin (IL)-18 is a proinflammatory cytokine that plays an important role in both innate and adaptive immune responses against several infectious pathogens. Relatively little is known about its production in HIV-1 infection, and there are controversial data on the influence
Magdalena Olszanecka-Glinianowicz et al.
Metabolism: clinical and experimental, 60(4), 531-536 (2010-06-29)
Obesity is associated with subclinical, chronic, and systemic immune activation characterized by increased serum concentration of proinflammatory cytokines released by adipose tissue. The aim of the present study was to determine the relationship between stage of development of obesity and
E J Pesonen et al.
Anesthesiology, 91(2), 355-361 (1999-08-12)
To study the effect of nitecapone, a novel antioxidant, on cardiac neutrophil activation during cardiopulmonary bypass in patients. In a double-blind, placebo controlled trial, 30 male patients undergoing coronary artery bypass grafting were randomly assigned to control (crystalloid cardioplegia, n
Christine M Pfeiffer et al.
The Journal of nutrition, 143(6), 957S-965S (2013-04-12)
Biochemical indicators of water-soluble vitamin (WSV) status were measured in a nationally representative sample of the U.S. population in NHANES 2003-2006. To examine whether demographic differentials in nutritional status were related to and confounded by certain variables, we assessed the
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