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Jun Akiba et al.
Oncology reports, 20(6), 1329-1335 (2008-11-21)
N-myc downstream regulated gene 1 (NDRG1)/Cap43 is a 43 kDa protein that is widely distributed in the body. Its expression is regulated by nickel, cobalt, hypoxic condition and others; it is reported to be weaker in tumors than normal tissues;
Farhad Ravandi et al.
Cancer, 118(10), 2665-2673 (2011-10-25)
IDH1 and IDH2 gene mutations are novel, recurring molecular aberrations among patients with normal karyotype acute myeloid leukemia (AML). Among 358 patients with AML treated on 4 protocols using high-dose ara-C plus idarubicin induction, pretreatment samples were available for 170
Satu Kalliola et al.
The Journal of allergy and clinical immunology, 131(3), 730-735 (2013-02-06)
Exposure to tobacco smoke is a well-known risk factor for childhood asthma and reduced lung function, but the effect on airway inflammation in preschool-aged children is unclear. To examine the effect of parental smoking on lung function and fractional concentration
Matthias Schwab et al.
Clinical pharmacology and therapeutics, 78(6), 627-634 (2005-12-13)
The clinical outcome of acid-related disorders treated by proton pump inhibitors (PPIs) might be dependent on the polymorphically expressed cytochrome P450 (CYP) 2C19, which is involved in PPI metabolism. We tested whether esomeprazole-induced healing of gastroesophageal reflux disease (GERD) is
Teerha Piratvisuth et al.
PloS one, 8(2), e54279-e54279 (2013-02-08)
The Roadmap concept is a therapeutic framework in chronic hepatitis B for the intensification of nucleoside analogue monotherapy based on early virologic response. The efficacy and safety of this approach applied to telbivudine treatment has not been investigated. A multinational
Claudia Gentili et al.
Journal of cellular biochemistry, 88(6), 1157-1167 (2003-03-21)
In rat enterocytes, signaling through the parathyroid hormone (PTH)/PTH-related peptide receptor type 1(PTHR1) includes stimulation of adenylyl cyclase, increases of intracellular calcium, activation of phospholipase C, and the MAP kinase pathway, mechanisms that suffer alterations with ageing. The purpose of
Lang Li et al.
Zhonghua yi xue za zhi, 90(8), 558-563 (2010-04-07)
To determine the role of extracellular signal-regulated kinases1/2 (ERK1/2) signaling pathway in regulating myocardial inflammation and cardiac function in a rat model of coronary microembolization (CME). The Sprague-Dawley rats were randomly divided into three groups: sham-operated group (n = 15)
Roos M Smits et al.
The Cochrane database of systematic reviews, 3, CD007411-CD007411 (2019-03-14)
The inability to have children affects 10% to 15% of couples worldwide. A male factor is estimated to account for up to half of the infertility cases with between 25% to 87% of male subfertility considered to be due to
National Toxicology Program technical report series, 477, 1-264 (2003-02-07)
1-Chloro-2-propanol and its positional isomer, 2-chloro-1-propanol, are used as chemical intermediates for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycol. The National Cancer Institute nominated 1-chloro-2-propanol for study because of potential for
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