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显示 31-60 共 90 条结果 关于 "109-12-6" 范围 论文
Judith R Stabel et al.
Veterinary immunology and immunopathology, 225, 110060-110060 (2020-05-16)
Animal infection models to study Mycobacterium avium subsp. paratuberculosis (MAP) infection are useful for evaluating the efficacy of vaccines and other therapeutics for the prevention or treatment of infection. The goal of the present study was to compare smaller ruminants
Chee-Keong Toh et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 5(1), 17-22 (2009-10-31)
Epidermal growth factor receptor (EGFR) mutations are more common in lung adenocarcinoma and in female patients of East-Asian origin. We aimed to assess the expression of female hormone receptors in East-Asian lung adenocarcinomas, their correlation with EGFR mutations, and prognostic
Kelsey R Thomas et al.
Psychiatric rehabilitation journal, 40(1), 70-78 (2016-08-23)
This study explored whether age moderated cognitive, symptom, and functional changes over a 12-week compensatory cognitive training (CCT) intervention for participants with severe mental illnesses. CCT focused on the cognitive domains of attention, learning, prospective memory, and executive functioning, often
Susumu Hijioka et al.
Pancreas, 43(3), 367-372 (2014-03-14)
This study investigated whether a risk assessment nomogram can predict the malignant potential of intraductal papillary mucinous neoplasms (IPMNs) and provide valuable information for the follow-up and counseling strategies of such patients. We studied 126 of 589 patients with IPMN
Alexandre A da Silva et al.
Hypertension (Dallas, Tex. : 1979), 47(2), 259-264 (2005-12-29)
Previous studies suggest that blockade of melanocortin 3 and 4 receptors (MC3/4-R) markedly attenuates the chronic hypertensive effects of leptin. Although obesity has been reported to be associated with leptin "resistance," it is unclear whether obesity alters the cardiovascular and
V Dhanda et al.
The Indian journal of medical research, 133, 110-115 (2011-02-16)
Group A streptococcal (GAS) pharyngitis, especially among children, leads to high prevalence of rheumatic fever (RF)/rheumatic heart disease (RHD) in India, as compared to the western world where invasive diseases are common. GAS encodes numerous virulence factors that cause diseases
Michael S Henson et al.
American journal of veterinary research, 72(8), 1052-1058 (2011-08-02)
To evaluate and compare circulating concentrations of islet amyloid polypeptide (IAPP), insulin, and glucose in nondiabetic cats classified by body condition score (BCS) and in cats with naturally occurring diabetes mellitus. 109 (82 nondiabetic, 21 nonketoacidotic diabetic, and 6 ketoacidotic
Sylvia Reitter-Pfoertner et al.
Thrombosis research, 130(3), 445-450 (2012-03-10)
To date, numerous mutations resulting in haemophilia A are known and recorded at HAMSTeRS. We identified a new splice site mutation in intron 6 of the F8 gene (T to G transition at position -14; c.788-14T>G) in seven not knowingly
Kris V Kowdley et al.
Lancet (London, England), 381(9883), 2100-2107 (2013-03-19)
The uridine nucleotide analogue sofosbuvir is a selective inhibitor of hepatitis C virus (HCV) NS5B polymerase. We assessed the safety and efficacy of sofosbuvir in combination with pegylated interferon alfa-2a (peginterferon) and ribavirin in non-cirrhotic treatment-naive, patients with HCV. For
Michelle D Spotnitz et al.
Circulation. Arrhythmia and electrophysiology, 7(6), 1136-1143 (2014-11-08)
Adenosine can unmask dormant pulmonary vein conduction after isolation. The role of adenosine in uncovering dormant accessory pathway (AP) conduction after AP ablation is unknown. We evaluated 109 consecutive patients (age, 41 ± 28 years; 62 [57%] men) who were
Aya Umeno et al.
PloS one, 8(5), e63542-e63542 (2013-05-22)
Current diagnostic tests such as glycemic indicators have limitations for early detection of impaired glucose tolerance (IGT), which leads to diabetes. Oxidative stress induced by various oxidants in a random and destructive manner is considered to play an important role
Martin Schillinger et al.
Thrombosis and haemostasis, 91(3), 610-618 (2004-02-26)
Low serum albumin is a powerful predictor of cardiovascular adverse events in healthy subjects and patients with subclinical, atherosclerosis. We investigated the association between serum albumin, traditional cardiovascular risk factors, markers of inflammation and cardiovascular outcome in 515 patients with
Thomas Pezawas et al.
Journal of cardiology, 65(6), 479-486 (2014-08-30)
Pulmonary vein isolation (PVI) has become an accepted therapy for patients with atrial fibrillation (AF) and the indications have widened to include non-paroxysmal AF-patients. Maintenance of sinus rhythm after PVI can be adversely affected by clinical or echocardiographic parameters, which
Burcin Ozüyaman et al.
Thrombosis and haemostasis, 93(6), 1161-1167 (2005-06-22)
Endothelial NO synthase (eNOS) expressed in the vascular endothelium or formed within platelets was postulated to inhibit platelet activation and aggregation. We have assessed the role of eNOS in platelet aggregation in vitro and in vivo by comparison of WT
Xiaolong Gao et al.
Biophysical journal, 104(4), 786-797 (2013-02-28)
Previous cysteine scanning studies of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel have identified several transmembrane segments (TMs), including TM1, 3, 6, 9, and 12, as structural components of the pore. Some of these TMs such as TM6
Dorothe Burggraf et al.
Thrombosis and haemostasis, 89(6), 1072-1080 (2003-06-05)
While recombinant tissue plasminogen activator (rt-PA) is successfully used in human ischemic stroke, it may also cause hemorrhagic complications. Animal experiments have shown that hemorrhages are related to microvascular basal lamina damage. We investigated the effects of different doses of
Wen-Chien Chou et al.
Blood, 116(20), 4086-4094 (2010-08-10)
Mutations in the additional sex comb-like 1 (ASXL1) gene were recently shown in various myeloid malignancies, but they have not been comprehensively investigated in acute myeloid leukemia (AML). In this study, we analyzed ASXL1 mutations in exon 12 in 501
Gérard Cam et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(4), 1554-1558 (2011-09-21)
Among the vitamin K antagonists (VKA), indanedione-derived VKA is suspected to induce an immunoallergic risk. One indanedione-derived VKA, fluindione, is still being used in France. The aim of this study was to evaluate the contribution of VKA to acute and
F Niroomand et al.
Naunyn-Schmiedeberg's archives of pharmacology, 354(5), 643-649 (1996-11-01)
Although both opioid receptors and endogenous opioids are abundant in cardiac tissues, the signal transduction pathways of opioids in cardiac sarcolemmal membranes have yet to be identified. In highly purified canine cardiac sarcolemmal membranes, binding of the opioid receptor antagonist
J Míguez et al.
Food chemistry, 135(3), 1310-1315 (2012-09-08)
A new and simple liquid chromatography tandem mass-spectrometry method for the determination of different bisphenol A (BPA) derivatives such as bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) and their reaction products with water and hydrochloric acid in
Masaya Itoda et al.
Drug metabolism and pharmacokinetics, 17(6), 566-571 (2004-12-25)
Twelve novel single nucleotide polymorphisms (SNPs) were found in the gene encoding the ATP-binding cassette transporter, P-glycoprotein, from 60 Japanese individuals who were administered the anti-antiarrythmic drug, amiodarone. The detected SNPs were as follows: 1) SNP, MPJ6_AB1017 (IVS6-109); GENE NAME
Han Joo Cho et al.
American journal of ophthalmology, 156(6), 1192-1200 (2013-09-10)
To evaluate the effect of choroidal vascular hyperpermeability, as determined using indocyanine green angiography (ICGA), on the outcome of anti-vascular endothelial growth factor (VEGF) treatment for polypoidal choroidal vasculopathy (PCV). Retrospective comparative series. Based on the presence of choroidal vascular
Benjamin Speich et al.
The Lancet. Infectious diseases, 15(3), 277-284 (2015-01-16)
Existing anthelmintic drugs (eg, albendazole and mebendazole) have low efficacy against the intestinal nematode species Trichuris trichiura and the drug pipeline is exhausted. We aimed to investigate the strategy of combination chemotherapy with existing drugs to establish whether their efficacy
Ocilon Gomes Sá Filho et al.
Animal reproduction science, 112(1-2), 95-106 (2008-05-13)
Three experiments evaluated effects of estradiol (E(2)) and/or progesterone (P(4)) prior to induction of ovulation with GnRH on subsequent luteal lifespan in anestrous Nelore cows. In Experiment 1, cows (25-65 days post-partum [DPP]; n=114) were assigned randomly to receive a
Jonathan Rice et al.
PloS one, 10(4), e0121948-e0121948 (2015-04-09)
There are increasing reports of plasma miRNAs as biomarkers of human disease but few standards in methodologic reporting, leading to inconsistent data. We systematically reviewed plasma miRNA studies published between July 2013-June 2014 to assess methodology. Six parameters were investigated:
Natan D da Silva et al.
Genes, 14(1) (2023-01-22)
Patients with peripheral artery disease (PAD) have reduced muscle capillary density. Walking training (WT) is recommended for PAD patients. The goal of the study was to verify whether WT promotes angiogenesis in PAD-affected muscle and to investigate the possible role
Jie Gao et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 41(9), 595-598 (2012-11-20)
To investigate mutations of KRAS gene and clinicopathological characteristics of colorectal carcinomas (CRC) in Chinese. Tumor cells were collected by microdissection from paraffin-embedded tumor specimens and adjacent normal colon tissues from 167 CRC patients. Genomic DNA was extracted and mutations
G R Aguilar Peralta et al.
International angiology : a journal of the International Union of Angiology, 26(4), 378-384 (2007-12-20)
Clinical and capillaroscopic evaluation of an association of Ruscus aculeatus, hesperidin methylchalcone (HMC) and ascorbic acid in chronic venous insufficiency A prospective, multicenter and open clinical study. Chronic venous insufficiency patients were studied using clinical, etiological, anatomical, physiological classification (CEAP)
Allen L Cohn et al.
Clinical colorectal cancer, 10(3), 171-177 (2011-08-23)
This prospective analysis evaluated the effect of tumor KRAS status on efficacy of second-line panitumumab plus folinic acid/5-fluorouracil/irinotecan (FOLFIRI). This phase 2, open-label, single-arm study enrolled patients with unresectable, measurable metastatic colorectal cancer (mCRC) after failure of first-line treatment with
J Esteban et al.
Haemophilia : the official journal of the World Federation of Hemophilia, 23(6), e488-e496 (2017-09-30)
Factor XI (FXI) deficiency is a rare disorder with molecular heterogeneity in Caucasians but relatively frequent and molecularly homogeneous in certain populations. To characterize FXI deficiency in a Spanish town of 60 000 inhabitants. A total of 324 764 APTT tests were
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