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Jung Won Lee et al.
Antimicrobial agents and chemotherapy, 59(12), 7629-7636 (2015-09-30)
Finafloxacin is a novel fluoroquinolone with improved antimicrobial efficacy, especially in an acidic environment. The efficacy of finafloxacin for the inhibition of Helicobacter pylori infection was compared with the efficacies of levofloxacin and moxifloxacin at neutral and acidic pH. The
Stewart J Tepper et al.
Mayo Clinic proceedings, 86(10), 948-955 (2011-10-04)
To evaluate the efficacy of MAP0004, an orally inhaled dihydroergotamine, for acute treatment of migraine when administered at various time points from within 1 hour to more than 8 hours after migraine onset. This post hoc subanalysis was conducted using
Thalia Wong et al.
Pediatric blood & cancer, 60(9), 1424-1430 (2013-04-25)
Iodine-131-metaiodobenzylguanidine ((131)I-MIBG) provides targeted radiotherapy for children with neuroblastoma. The aim of our study was to evaluate systematically the acute effects of (131)I-MIBG on blood pressure in patients with neuroblastoma and to identify possible predictors of hypertension. We conducted a
D B Warheit et al.
Drug and chemical toxicology, 13(1), 1-18 (1990-01-01)
Acrawax is a trademark for a series of synthetic waxes which are used as flatteners in paint, and lubricants in plastics, and these materials have been routinely regarded as nuisance dusts. Due to a paucity of information regarding the pulmonary
Yantao Du et al.
BMC cancer, 12, 249-249 (2012-06-19)
Many miR genes are located within or around CpG islands. It is unclear whether methylation of these CpG islands represses miR transcription regularly. The aims of this study are to characterize gastric carcinoma (GC)-related methylation of miR CpG islands and
Linlong Wang et al.
Journal of applied toxicology : JAT, 34(8), 870-877 (2013-07-03)
Quinolones have been reported to induce adverse effects on articular cartilage, tendons and ligaments. However, the effects of quinolones on menisci have not been revealed. The present study was to test the effects of levofloxacin on meniscus cells in vitro.
M Nishimura et al.
Human immunology, 61(12), 1262-1269 (2001-02-13)
We studied tumor necrosis factor (TNF), lymphotoxin-alpha (LT-alpha), and TNF receptors type 1 (TNFR-1) and type 2 (TNFR-2) gene polymorphisms as well as HLA class II DRB1 alleles in Japanese patients with human T-cell lymphotropic virus type I (HTLV-I) associated
S J Garcés-Eisele et al.
Journal of clinical pharmacy and therapeutics, 39(4), 368-375 (2014-04-08)
Hydralazine is an inhibitor of DNA methyltransferases, whereas valproate interferes with histone deacetylation. In combination, they show a marked synergism in reducing tumour growth as well as development of metastasis and inducing cell differentiation. Hydralazine is metabolized by the highly
Yao Bang Lu et al.
Journal of human genetics, 50(7), 338-346 (2005-08-02)
Deficiency of citrin, a liver-type mitochondrial aspartate-glutamate carrier (AGC), encoded by the SLC25A13 gene on chromosome 7q21.3, causes autosomal recessive disorders: adult-onset type II citrullinemia (CTLN2) and neonatal hepatitis associated with intrahepatic cholestasis (NICCD). So far, we have described 12
T Furuta et al.
Alimentary pharmacology & therapeutics, 26(5), 693-703 (2007-08-19)
Polymorphism in MDR1 is associated with variation in the plasma level of a proton pump inhibitor. To investigate whether MDR1 polymorphism is associated with eradication rates of Helicobacter pylori by a triple therapy with lansoprazole, amoxicillin and clarithromycin in relation
Shinichi Aishima et al.
Human pathology, 38(12), 1819-1825 (2007-09-15)
Aquaporin-1 (AQP-1) has been found to be important in bile formation across cell membranes of the biliary epithelium, and thus it has been suggested that AQP-1 is involved in the pathogenesis of hepatobiliary disease. To clarify the role of AQP-1
Hong-Bin Ji et al.
The Journal of biological chemistry, 277(49), 47898-47906 (2002-09-27)
T cell-specific expression of human and mouse CD3delta is known to be governed by an enhancer element immediately downstream from the gene. Here we demonstrate by transgenic and in vitro studies that the murine CD3delta (mCD3delta) promoter prefers to be
Y Miyagoe et al.
The Journal of biological chemistry, 269(11), 8268-8279 (1994-03-18)
We have explored the template and factor requirements for transcription of the gene encoding the murine complement component C4, expressed predominantly but not exclusively in liver and mononuclear phagocytes. Competition experiments in transcription assays with liver nuclear extracts show that
Bryan Ballantyne et al.
Journal of applied toxicology : JAT, 23(5), 301-314 (2003-09-17)
Ethylene glycol monohexyl ether (EGHE; CAS no. 112-54-4) is a liquid industrial chemical with a potential for skin contact. The toxicokinetics of EGHE was investigated in Fischer 344 rats and New Zealand White rabbits by intravenous (i.v.) and 48-h occluded
J R Cockcroft et al.
British journal of clinical pharmacology, 38(4), 317-321 (1994-10-01)
1. The effect of icatibant (D-Arg-[Hyp3, Thi5, D-Tic7, Oic8] bradykinin) a potent B2-kinin receptor antagonist, was studied on bradykinin-induced vasodilation in the human forearm. 2. Eight healthy normotensive men were studied in a rising dose random-placebo controlled study. Placebo and
K Raile et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 35(11-12), 786-793 (2004-01-08)
Insulin-like growth factor-I (IGF-I) was found to promote proliferation, cell survival, and inhibition of apoptosis. But in some instances, IGF-I was found to mildly induce apoptosis, i. e. Fas-mediated apoptosis in human MG63 osteosarcoma cells. In the present study, we
Jana Beinhauer et al.
Analytica chimica acta, 858, 74-81 (2015-01-20)
Estrone (E1), estradiols (α/β-E2), and estriol (E3) are four major metabolically active estrogens exerting strong biological activities at very low circulating concentrations. This paper reports a sensitive and efficient method with automated, on-line clean-up and detection to determine trace estrogens
Antonia María Toledano et al.
Journal of food science and technology, 56(1), 122-131 (2019-02-08)
The behaviour of two combined starter cultures and their influence on the microbiological and physicochemical characteristics of dry-cured ham have been evaluated. Three lots of dry-cured hams were tested during processing (0, 9, 48, 74, 112, 142, 166 and 211 days).
Yao-Yuan Hsieh et al.
Fertility and sterility, 91(3), 869-877 (2009-01-30)
To investigate whether the gene polymorphisms for p21, X-ray repair cross-complementing group 1 (XRCC1), human 8-oxoguanine glycosylase 1 (hOGG1), and dopamine D1 and D2 receptors (DRD1, -2) are associated with leiomyoma susceptibility. Prospective study. Departments of gynecology and genetics in
A H van Lierop et al.
The Journal of clinical endocrinology and metabolism, 97(10), E1953-E1957 (2012-07-31)
Increased bone fragility is a frequent complication of hypercortisolism due predominantly to suppression of bone formation. Sclerostin is an osteocyte-produced negative regulator of bone formation, which is up-regulated by glucocorticoids in mice. Our objective was to assess the effect of
Shuangyu Lv et al.
Frontiers in pharmacology, 11, 574607-574607 (2021-02-02)
Βeta-cyclodextrin (β-CD) with a hydrophobic cavity enables the formation of inclusion complexes with organic molecules. The formation of host-guest complexes makes the application of β-CD popular in many fields, but their interaction with organisms is poorly understood. In the present
Patricia C Valery et al.
The Lancet. Respiratory medicine, 1(8), 610-620 (2014-01-28)
Indigenous children in high-income countries have a heavy burden of bronchiectasis unrelated to cystic fibrosis. We aimed to establish whether long-term azithromycin reduced pulmonary exacerbations in Indigenous children with non-cystic-fibrosis bronchiectasis or chronic suppurative lung disease. Between Nov 12, 2008
M L Rothenberg et al.
Gynecologic oncology, 82(2), 317-322 (2001-09-05)
The aim of this study was to evaluate the 2-year survival rate in a group of women in complete clinical remission (cCR) from Stage III ovarian cancer following front-line therapy who were then treated with a 6-month course of altretamine.
Babbette LaMarca et al.
Hypertension (Dallas, Tex. : 1979), 52(6), 1168-1172 (2008-10-15)
Circulating factors, such as agonistic autoantibodies to the angiotensin II type 1 (AT1) receptor (AT1-AAs), and inflammatory cytokines, including tumor necrosis factor alpha (TNF-alpha), are suggested to be important links between placental ischemia and hypertension in preeclamptic women. The purpose
Jaeung Sim et al.
Dalton transactions (Cambridge, England : 2003), 43(48), 18017-18024 (2014-10-30)
Three functionalized metal-organic frameworks (MOFs), MOF-205-NH2, MOF-205-NO2, and MOF-205-OBn, formulated as Zn4O(BTB)4/3(L), where BTB is benzene-1,3,5-tribenzoate and L is 1-aminonaphthalene-3,7-dicarboxylate (NDC-NH2), 1-nitronaphthalene-3,7-dicarboxylate (NDC-NO2) or 1,5-dibenzyloxy-2,6-naphthalenedicarboxylate (NDC-(OBn)2), were synthesized and their gas (H2, CO2, or CH4) adsorption properties were compared to
Lilliana Morales-Vásquez et al.
Puerto Rico health sciences journal, 33(4), 177-183 (2015-01-08)
To describe the risk factors for infection, complications, treatment received and response in Puerto Ricans with HCV attending gastroenterology clinics at UPR-MSC, and the prevalence of single nucleotide polymorphisms (SNPs) in IFNL3 and IFNL4 in this population. After consent, demographic
Richard J Caselli et al.
Archives of neurology, 64(9), 1306-1311 (2007-09-12)
Memory declines more rapidly with age in apolipoprotein E (APOE) epsilon4 carriers than in APOE epsilon4 noncarriers, and APOE epsilon4 homozygotes' cognitive performances correlate with stressors. These changes could represent presymptomatic disease in some, despite their youth. To show that
Kenji Sugai
Epilepsia, 45 Suppl 8, 20-25 (2004-12-22)
To confirm the efficacy and to clarify the problems of clobazam (CLB) as a new antiepileptic drug (AED) and clorazepate (CLP) as an alternative AED in Japan. CLB and CLP were added on or replaced with conventional AEDs in 55
José Ramón Blanco et al.
HIV clinical trials, 14(5), 204-215 (2013-10-23)
Current antiretroviral guidelines state that being older than 50 to 55 years of age is an indication to start antiretroviral therapy (ART), regardless of CD4 status. However, no references to the preferred combination ART (cART) for these patients have been
A M Zealand et al.
Applied microbiology and biotechnology, 102(19), 8599-8612 (2018-07-28)
Anaerobic digestion (AD) uses a range of substrates to generate biogas, including energy crops such as globally abundant rice straw (RS). Unfortunately, RS is high in lignocellulosic material and has high to C:N ratios (~80:1), which makes it (alone) a
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