112-79-8

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Alternative antiandrogen therapy in patients with castration-resistant prostate cancer: a single-center experience.

Takatsugu Okegawa et al.

International journal of urology : official journal of the Japanese Urological Association, 17(11), 950-955 (2010-09-03)

Outcomes of alternative (second-line) antiandrogen therapy in 112 patients with relapsing prostate cancer after first-line hormonal therapy were analyzed. A good response (prostate-specific antigen [PSA] decrease 50%) and a partial response (PSA decrease of 0–50%) by switching from bicalutamide (BCL)

Oxygen supply modulates MCP-1 release in monocytes from young and aged rats: decrease of MCP-1 transcription and translation is age-related.

M Reale et al.

Molecular and cellular biochemistry, 248(1-2), 1-6 (2003-07-23)

Hyper or hypoxia may affect the immune system's chemokine production. Monocyte chemotactic protein-1 (MCP-1), an important chemotactic cytokine can be activated by active oxygen species. Groups of rats were exposed to hypoxic and hyperoxic environmental conditions for 60 h and

Development of an ELISA for detection of mitragynine and its metabolites in human urine.

Mei Jin Lee et al.

Analytical biochemistry, 599, 113733-113733 (2020-04-18)

An enzyme-linked immunosorbent assay for detection of mitragynine, other closely related Kratom alkaloids and metabolites was developed using polyclonal antibodies. Mitragynine was conjugated to a carrier protein, cationized-bovine serum albumin using Mannich reaction. The synthesized antigen was injected into rabbits

Endoscopic surveillance of patients with hereditary diffuse gastric cancer: biopsy recommendations after topographic distribution of cancer foci in a series of 10 CDH1-mutated gastrectomies.

Hiroshi Fujita et al.

The American journal of surgical pathology, 36(11), 1709-1717 (2012-10-18)

The management of hereditary diffuse-type gastric cancer revolves around surveillance biopsies and the timing of prophylactic gastrectomy. In the absence of a validated surveillance biopsy protocol, we modeled bioptic diagnostic yield on the basis of the topographic distribution of cancer

The complete title: The effect of interleukin-28B rs12979860 polymorphism on the therapeutic response of Moroccan patients with chronic hepatitis C.

Kandoussi Nadia et al.

Gene, 568(1), 31-34 (2015-05-11)

There is increasing evidence for the effect of rs12979860 IL28B polymorphism in response to the standard treatment PEG-IFN/RBV (i.e. combination of pegylated interferon and ribavirin) in chronic hepatitis C virus (HCV) infection. The present study aimed to determine the impact

Impact of clinical characteristics and management on the prognosis of unselected heart failure patients.

Romain Eschalier et al.

Cardiovascular drugs and therapy, 29(1), 89-98 (2015-02-24)

Heart failure (HF) is a major public health issue. This study conducted a real-life analysis of the impact of clinical characteristics and medical management of HF on its prognosis. Analysis was based on the EGB ("Echantillon Généraliste des Bénéficiaires") database.

Leptin receptor polymorphism is associated with serum lipid levels and impairment of cholesterol lowering effect by simvastatin in Japanese men.

Akiko Takahashi-Yasuno et al.

Diabetes research and clinical practice, 62(3), 169-175 (2003-11-20)

To investigate whether leptin receptor (Ob-R) Arg223Gln polymorphism influences serum lipid levels and whether this polymorphism affects the efficiency of the cholesterol lowering HMG-CoA reductase inhibitor, simvastatin [Clin. Cardiol. 16 (1993) 317]. Case-control association study. We studied 201 Japanese men

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