112-84-5

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Postmastectomy hypofractionated and accelerated radiation therapy with (and without) subcutaneous amifostine cytoprotection.

Michael I Koukourakis et al.

International journal of radiation oncology, biology, physics, 85(1), e7-13 (2012-10-09)

Postmastectomy radiation therapy (PMRT) provides major local control and survival benefits. More aggressive radiation therapy schemes may, however, be necessary in specific subgroups, provided they are safely administered. We report the tolerance and efficacy of a highly accelerated and hypofractionated

Effect of selection for lifetime production of lamb weaned on hormonal factors that affect growth in Targhee ewes and lambs.

W A Head et al.

Journal of animal science, 74(9), 2152-2157 (1996-09-01)

Targhee ewes (n = 22, average age 5 yr) rearing twin lambs were used to investigate serum growth hormone (GH), IGF-I, triiodothyronine (T3), thyroxine (T4), and prolactin (PRL; ewes only) concentrations associated with selection pressure for lifetime production of kilograms

Interim analysis for post-marketing surveillance of dabrafenib and trametinib combination therapy in Japanese patients with unresectable and metastatic melanoma with BRAF V600 mutation.

Yasutomo Teshima et al.

International journal of clinical oncology, 25(10), 1870-1878 (2020-07-24)

To investigate the safety and efficacy of dabrafenib and trametinib combination therapy for BRAF V600 mutation-positive unresectable and metastatic melanoma in over 100 Japanese patients of a real-world clinical setting. The surveillance period of interim post-marketing surveillance (PMS) analysis was

[Expression pattern and clinical significance of hairy enhancer of split 1 in colorectal cancer].

Hei-ying Jin et al.

Zhonghua yi xue za zhi, 91(41), 2891-2894 (2012-02-16)

To explore the roles of hairy enhancer of split 1 (Hes1) gene in colorectal cancer and analyze its clinical significance. A total of 146 cases with colorectal cancer at our hospital were collected prospectively and followed up. There were 84

Fluctuation of potential zinc status biomarkers throughout a reproductive cycle of primiparous and multiparous sows.

Miriam M J van Riet et al.

The British journal of nutrition, 114(4), 544-552 (2015-07-23)

Fluctuations in Zn metabolism throughout gestation and lactation might affect Zn requirements. However, scientific data on Zn requirements for breeding sows are limited. The objective of the present study was to assess the Zn status of primiparous and multiparous sows

Phase I and pharmacokinetic study of the novel anthracycline derivative 5-imino-13-deoxydoxorubicin (GPX-150) in patients with advanced solid tumors.

Sarah A Holstein et al.

Investigational new drugs, 33(3), 594-602 (2015-02-24)

5-imino-13-deoxydoxorubicin (DIDOX; GPX-150) is a doxorubicin analog modified in two locations to prevent formation of cardiotoxic metabolites and reactive oxygen species. Preclinical studies have demonstrated anti-cancer activity without cardiotoxicity. A phase I study was performed in order to determine the

Evaluation of the dietary vitamin A requirement of finishing steers via systematic depletion and repletion, and its effects on performance and carcass characteristics.

Kimberly B Wellmann et al.

Journal of animal science, 98(9) (2020-08-20)

A randomized complete block design experiment with 30 yearling crossbred steers (initial average body weight [BW] = 297.6 ± 32.8 kg) fed a steam-flaked corn-based diet was used to evaluate finishing performance and carcass characteristics when provided with different concentrations

The sedlin gene for spondyloepiphyseal dysplasia tarda escapes X-inactivation and contains a non-canonical splice site.

S Mumm et al.

Gene, 273(2), 285-293 (2001-10-12)

Mutations in the sedlin gene cause spondyloepiphyseal dysplasia tarda (SEDT), a rare X-linked chondrodysplasia. Affected males suffer short stature, deformation of the spine and hips, and deterioration of intervertebral discs with characteristic radiographic changes in the vertebrae. We have sequenced

Solution structure of calcium-bound rat S100B(betabeta) as determined by nuclear magnetic resonance spectroscopy,.

A C Drohat et al.

Biochemistry, 37(9), 2729-2740 (1998-04-16)

The three-dimensional structure of Ca2+-bound rat S100B(betabeta) has been determined using data from a series of two-dimensional (2D), three-dimensional (3D), and four-dimensional (4D) nuclear magnetic resonance (NMR) experiments. Each S100beta subunit (91 residues) contains four helixes (helix 1, E2-R20; helix

Addition of rituximab to chlorambucil produces superior event-free survival in the treatment of patients with extranodal marginal-zone B-cell lymphoma: 5-year analysis of the IELSG-19 Randomized Study.

Emanuele Zucca et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(5), 565-572 (2013-01-09)

Apart from localized gastric disease, there is no consensus on standard initial treatment of mucosa-associated lymphoid tissue lymphoma. The IELSG-19 study (Randomized Trial of Chlorambucil Versus Chlorambucil Plus Rituximab Versus Rituximab in MALT Lymphoma) was launched to compare chlorambucil alone

Effect of calcium and cholecalciferol supplementation on several parameters of calcium status in plasma and urine of captive Asian (Elephas maximus) and African elephants (Loxodonta africana).

Gerda R van Sonsbeek et al.

Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 44(3), 529-540 (2013-09-26)

The aim of the current study was to assess the effect of oral calcium and cholecalciferol supplementation on several parameters of calcium status in plasma and urine of captive Asian (Elephas maximus; n=10) and African elephants (Loxodonta africana; n=6) and

Expression, epitope prediction and IgE-binding of the Tyrophagus putrescentiae group 13 allergen.

Nan Wang et al.

Experimental and therapeutic medicine, 20(5), 21-21 (2020-09-17)

Storage mites, such as Tyrophagus putrescentiae, are an important source of allergens that cause allergic diseases in humans. It has previously been indicated that T. putrescentiae has a high sensitization rate as an allergen in some Asian and European countries.

Expression of a novel oncofetal mRNA-binding protein IMP3 in endometrial carcinomas: diagnostic significance and clinicopathologic correlations.

Cuizhen Li et al.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(12), 1263-1268 (2007-09-22)

Insulin-like growth factor-II mRNA-binding protein 3 (IMP3) is a newly identified oncofetal mRNA-binding protein that is involved in embryogenesis and carcinogenesis of some malignant neoplasms. To investigate the diagnostic and clinicopathologic significance of this protein in endometrial carcinomas, we evaluated

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