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Susana Melo Gesteira et al.
PloS one, 14(4), e0216047-e0216047 (2019-04-27)
The objective of this study was to evaluate the effect of condensed tannin inclusion (0, 10, 30 or 50 g/kg of dry matter (DM) total) from Acacia mearnsii extract on the fatty acid profile, physicochemical quality and sensorial analysis of
A Cristea et al.
Journal of applied microbiology, 125(5), 1343-1357 (2018-06-22)
This study aimed at unprecedented physical and chemical evaluation of the 'green plastics' polyhydroxyalkanoates (PHAs), in an extremely halotolerant Halomonas elongata strain 2FF under high-salt concentration. The investigated bacterial strain was isolated from the surface water of the hypersaline Fără
Hnin Thanda Aung et al.
Bioorganic & medicinal chemistry, 19(7), 2392-2396 (2011-03-11)
In our previous paper, we reported that rosmarinic acid (1) of Argusia argentea could neutralize snake venom induced hemorrhagic action. Rosmarinic acid (1) consists of two phenylpropanoids: caffeic acid (2) and 3-(3,4-dihydroxyphenyl)lactic acid (3). In this study, we investigated the
Deepak Prasad Gupta et al.
Toxins, 12(4) (2020-04-23)
Neuroinflammation is involved in various neurological diseases. Activated microglia secrete many pro-inflammatory factors and induce neuronal cell death. Thus, the inhibition of excessive proinflammatory activity of microglia leads to a therapeutic effect that alleviates the progression of neuronal degeneration. In
K J Herrick et al.
Journal of dairy science, 101(4), 3524-3536 (2018-02-08)
The objective of this study was to investigate the effects on plasma metabolites and rumen traits when butyrate was infused into the rumen or abomasum of lactating cows. Jugular catheters were inserted into 5 ruminally fistulated Holstein cows [94.2 ±
Yu Qian et al.
Experimental and therapeutic medicine, 6(1), 228-232 (2013-08-13)
The aim of this study was to investigate the effects of resistant starch (RS) on activated carbon-induced constipation in ICR mice. ICR mice were fed on diet containing 15% RS of type RS2, RS3 or RS4 for 9 days. Gastrointestinal
S W Fessenden et al.
Journal of dairy science, 102(4), 3023-3035 (2019-02-26)
The objective of this study was to evaluate the effects of a fermentation byproduct on rumen fermentation and microbial yield in high producing lactating dairy cattle. Eight ruminally cannulated multiparous Holstein cows averaging (mean ± standard deviation) 60 ± 10
J L Gramkow et al.
Journal of animal science, 94(9), 3933-3946 (2016-11-30)
Two studies evaluated effects of replacing corn with a pellet containing alkaline treated corn stover, dried distillers' grains plus solubles (DDGS), and distillers' solubles on total tract digestion and performance of finishing cattle. Experiment 1 used 4 ruminally fistulated steers
Yi Peng et al.
Journal of chromatography. A, 1594, 45-53 (2019-02-26)
Conjugated microporous polymers (CMPs) with permanent microporosity and extended p-conjugated skeletons have recently shown the fascinating application in separation and enrichment. In this report, porphyrin CMP that possessed microporous structure and nitrogen-rich pyrrole building blocks was successfully synthesized by microwave-assisted
Masanori Matsuura et al.
Nature chemical biology, 5(7), 465-467 (2009-05-26)
We have isolated the small, highly strained carboxylic acid cycloprop-2-ene carboxylic acid from the Asian toxic mushroom Russula subnigricans. This compound is responsible for fatal rhabdomyolysis, a new type of mushroom poisoning that is indicated by an increase in serum
Qi Wang et al.
Cell reports, 31(3), 107528-107528 (2020-04-23)
Identification of multiple histone acylations diversifies transcriptional control by metabolism, but their functions are incompletely defined. Here we report evidence of histone crotonylation in the human fungal pathogen Candida albicans. We define the enzymes that regulate crotonylation and show its
Wei Jin et al.
Antonie van Leeuwenhoek, 111(11), 2037-2049 (2018-05-19)
The cecum plays an important role in the feed fermentation of ruminants. However, information is very limited regarding the cecal microbiota and their methane production. In the present study, the cecal content from twelve local Chinese goats, fed with either
Justyna Grabska et al.
The journal of physical chemistry. A, 121(18), 3437-3451 (2017-04-18)
By near-infrared (NIR) spectroscopy and anharmonic density functional theory (DFT) calculations, we investigate five kinds of saturated and unsaturated carboxylic acids belonging to the group of short-chain fatty acids: propionic acid, butyric acid, acrylic acid, crotonic acid, and vinylacetic acid.
Chenglei Tian et al.
Cell reports, 29(13), 4256-4267 (2019-12-26)
The generation of genomically stable and functional oocytes has great potential for preserving fertility and restoring ovarian function. It remains elusive whether functional oocytes can be generated from adult female somatic cells through reprogramming to germline-competent pluripotent stem cells (gPSCs)
Enrico Orsi et al.
Journal of industrial microbiology & biotechnology, 46(8), 1179-1190 (2019-06-13)
Rhodobacter sphaeroides is a metabolically versatile bacterium capable of producing terpenes natively. Surprisingly, terpene biosynthesis in this species has always been investigated in complex media, with unknown compounds possibly acting as carbon and nitrogen sources. Here, a defined medium was
Zhituo Yu et al.
Applied microbiology and biotechnology, 103(23-24), 9593-9606 (2019-11-13)
FK520 (ascomycin), a 23-membered macrolide with immunosuppressive activity, is produced by Streptomyces hygroscopicus. The problem of low yield and high impurities (mainly FK523) limits the industrialized production of FK520. In this study, the FK520 yield was significantly improved by strain
Apoorva Rao et al.
Biomolecules, 9(12) (2019-12-18)
The inexhaustible nature and biodegradability of bioplastics like polyhydroxyalkanoates (PHAs) make them suitable assets to replace synthetic plastics. The eventual fate of these eco-friendly and non-toxic bioplastics relies upon the endeavors towards satisfying cost and, in addition, execution necessity. In
Michael J McAnulty et al.
Biotechnology and bioengineering, 114(4), 852-861 (2016-11-02)
We previously demonstrated anaerobic conversion of the greenhouse gas methane into acetate using an engineered archaeon that produces methyl-coenzyme M reductase (Mcr) from unculturable microorganisms from a microbial mat in the Black Sea to create the first culturable prokaryote that
Johannes Waschke et al.
PloS one, 14(4), e0214815-e0214815 (2019-04-03)
Adhesive interactions of soft materials play an important role in nature and technology. Interaction energies can be quantified by determining contact areas of deformable microparticles with the help of reflection interference contrast microscopy (RICM). For high throughput screening of adhesive
D Vyas et al.
Journal of animal science, 93(8), 3950-3958 (2015-10-07)
The objective of this study was to determine whether supplementing organic acids can prevent incidences of subacute ruminal acidosis (SARA) in beef heifers fed a diet consisting of 8% barley silage and 92% barley grain-based concentrate (DM basis). Ten ruminally
Danqiu Lin et al.
Antonie van Leeuwenhoek, 112(6), 927-933 (2019-02-10)
Strain IO390502T, isolated from surface seawater in the Indian Ocean, was characterised using a polyphasic taxonomy approach. Phylogenetic analyses based on 16S rRNA gene sequences indicated that strain IO390502T belongs to the genus Paracoccus and is closely related to Paracoccus
Swelling Studies of Copolymeric Acrylamide/Crotonic Acid Hydrogels as Carriers for Agricultural Uses.
Karadag E, et al.
Polymers For Advanced Technologies, 11(2), 59-68 (2000)
J P D van Veldhoven et al.
Bioorganic & medicinal chemistry letters, 21(9), 2736-2739 (2010-12-21)
Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids and esters such as methyl fumarate also interact with the
Ruifeng Li et al.
Nature chemical biology, 14(7), 664-670 (2018-05-23)
Introduction of innovative biocatalytic processes offers great promise for applications in green chemistry. However, owing to limited catalytic performance, the enzymes harvested from nature's biodiversity often need to be improved for their desired functions by time-consuming iterative rounds of laboratory
Lei Wang et al.
Bioresource technology, 287, 121484-121484 (2019-05-24)
In this study, Y. lipolytica was engineered to produce crotonic acid via the butanol-forming route. Firstly, the crotonase and 3-hydroxybutyryl-CoA dehydrogenase genes from Clostridium beijerinckii, and the thioesterase gene from Bacteroides thetaiotaomicron were heterologously expressed in Y. lipolytica, the engineered
K J Herrick et al.
Journal of dairy science, 100(1), 757-768 (2016-11-14)
Several studies have identified beneficial effects of butyrate on rumen development and intestinal health in preruminants. These encouraging findings led to further investigations related to butyrate supplementation in the mature ruminant. However, the effects of elevated butyrate concentrations on rumen
Tanakarn Monshupanee et al.
Scientific reports, 6, 37121-37121 (2016-11-16)
Sustainable production of bioplastics by heterotrophic microbes has been restricted by the limited resources of organic substrates and the energy required for biomass harvest. Here, the easy-to-harvest cyanobacterium (Chlorogloea fritschii TISTR 8527), from which the biomass instantaneously settled to the
Modesto Millán et al.
Journal of biotechnology, 259, 50-55 (2017-08-24)
Poly-3-hydroxybutyrate (P3HB) is a biopolymer produced by Azotobacter vinelandii. The physicochemical properties and applications of P3HB are strongly influenced by its weight-average molecular mass (Mw), and in A. vinelandii, it could be influenced by the culture conditions. The aim of
Zhenxing Shi et al.
Food & function, 11(2), 1624-1634 (2020-02-06)
α-Amylase inhibitors (α-AI) have great potential to treat obesity. In this study, an α-AI enriched extract (α-AIE) with a specific activity of 1027.1 ± 154.2 (U per mg protein) was prepared from white common bean (Phaseolus vulgaris L.) seeds. Its
Reika Yoshitsugu et al.
Lipids in health and disease, 19(1), 9-9 (2020-01-17)
Previously, we found a significant relationship in a rat study between energy intake and bile acid (BA) metabolism especially 12α-hydroxylated (12αOH) BAs. The present study was designed to reveal relationships among BA metabolism, glucose tolerance, and cecal organic acids in
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