K G Bhansali et al.
Journal of pharmaceutical sciences, 76(8), 654-657 (1987-08-01)
The compound 1,2-benzo-8-(2-aminoethyl)-3-phenoxazone (1) is synthesized by reacting tyramine with 1-nitroso-2-naphthol in the presence of nitric acid. During the reaction, tyramine and 1-nitroso-2-naphthol undergo condensation, ring closure, and subsequent oxidation steps to form 1. Compound 1 is characterized by one-