CN
Search Within
122-52-1
应用筛选条件
关键词:'122-52-1'
显示 1-22 共 22 条结果 关于 "122-52-1" 范围 论文
Eun-Young Kim et al.
Clinica chimica acta; international journal of clinical chemistry, 411(23-24), 2043-2048 (2010-09-11)
We developed a CYP2D6 genotyping method that includes copy number variation (CNV) and recently known functional haplotypes using multiplex single-base extension (SBE). Twelve CYP2D6 alleles (*1, *2, *5, *10, *14, *18, *21, *41, *49, *52, *60, and a duplication of
S O'Neill et al.
The British journal of surgery, 100(13), 1689-1700 (2013-11-15)
Vascular clamping reduces blood loss during liver resection but leads to ischaemia-reperfusion injury. Ischaemic preconditioning (IP) may reduce this. This study aimed to evaluate IP in liver resection under clamping. This was a systematic review and meta-analysis of randomized clinical
Kazuyuki Tokumaru et al.
Bioorganic & medicinal chemistry, 25(12), 3098-3115 (2017-04-24)
G protein-coupled receptor 52 (GPR52) agonists are expected to improve the symptoms of psychiatric disorders. During exploration for a novel class of GPR52 agonists with good pharmacokinetic profiles, we synthesized 4-(3-(3-fluoro-5-(trifluoromethyl)benzyl)-5-methyl-1H-1,2,4-triazol-1-yl)-2-methylbenzamide (4u; half maximal effective concentration (EC50)=75nM, maximal response (Emax)=122%)
M Čandek-Potokar et al.
Veterinary journal (London, England : 1997), 204(2), 162-167 (2015-04-22)
The effect of adding hydrolysable tannins to the diet of fattening boars was studied. Performance, reproductive organ weights, salivary gland morphology, boar taint compounds and skatole metabolism were evaluated. At 123 days of age and 52 ± 6 kg liveweight, 24 Landrace × Large White
Christine Fritsch et al.
Arthritis research & therapy, 8(1), R4-R4 (2005-12-17)
Neonatal lupus erythematosus is a rare disorder caused by the transplacental passage of maternal autoantibodies. The 52-kDa Ro/SSA antigen (Ro52) ribonucleoprotein represents an antigenic target strongly associated with the autoimmune response in mothers whose children have neonatal lupus and cardiac
Kazutaka Hayashida et al.
Circulation, 112(6), 812-818 (2005-08-03)
Markers of cardiac injury, including troponin-T (TnT), are used to diagnose acute coronary syndrome (ACS); however, markers for plaque instability may be more useful for diagnosing ACS at the earliest stage. Lectin-like oxidized LDL receptor-1 (LOX-1) appears to play crucial
Sakhawat Hussain Rahman et al.
Digestive diseases and sciences, 50(7), 1376-1383 (2005-07-29)
Epidemiological studies have demonstrated a variety of potential environmental factors that may alter susceptibility to chronic pancreatitis (CP) through oxidative/xenobiotic stress; however, a direct causal and mechanistic role has not been established. We aimed (1) to determine the prevalence of
Limei Yang et al.
Thrombosis research, 125(4), e159-e166 (2009-11-28)
Warfarin is the most widely used oral anticoagulant. It has been suggested that anticoagulation effect of warfarin is significantly associated with the polymorphism of certain genes, including Cytochrome P450 complex subunit 2C9 (CYP2C9), Vitamin K Epoxide Reductase Complex Subunit 1
L Tarnow et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 16(8), 1653-1656 (2001-07-31)
An XbaI polymorphism in the gene encoding the glucose transporter, GLUT-1, is associated with development of diabetic nephropathy in Chinese type 2 diabetic patients. In addition, an amino acid variant (K121Q) in the gene encoding the glycoprotein plasma cell differentiating
M R Chruscielewska-Kiliszek et al.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 15(1), e48-e55 (2012-09-26)
Chronic radiation proctitis is a long-term complication of radiation therapy for pelvic malignancy. The aim of this study was to compare the efficacy and safety of two treatment regimens, sucralfate or placebo, following argon plasma coagulation (APC) for chronic haemorrhagic
M Terzolo et al.
European journal of endocrinology, 169(3), 263-270 (2013-05-25)
Mitotane plasma concentrations ≥ 14 mg/l have been shown to predict tumor response and better survival in patients with advanced adrenocortical carcinoma (ACC). A correlation between mitotane concentrations and patient outcome has not been demonstrated in an adjuvant setting. To
David J Hallett et al.
Organic & biomolecular chemistry, 10(30), 6130-6158 (2012-04-20)
Reactions of the allyltin trichloride 45 generated from (4S)-4-benzyloxypent-2-enyl(tributyl)stannane 1 with imines prepared from glyoxylates proceed with useful levels of 1,5-stereocontrol in favour of (4E)-2,6-anti-2-(alkylamino)-6-benzyloxyhept-4-enoates 49. This stereoselectivity, controlled by the chirality of the stannane, dominates over any intrinsic stereochemical
Niek Verweij et al.
Hypertension (Dallas, Tex. : 1979), 61(3), 602-608 (2013-02-06)
Endothelin-1 (ET-1) and adrenomedullin (ADM) are circulating vasoactive peptides involved in vascular homeostasis and endothelial function. Elevated levels of plasma ET-1 and ADM, and their biologically stable surrogates, C-terminal-pro-endothelin-1 (CT-pro-ET-1) and midregional proadrenomedullin (MR-pro-ADM), are predictors of cardiac death and
Christian Anderwald et al.
Molecular endocrinology (Baltimore, Md.), 16(7), 1612-1628 (2002-06-29)
Leptin has both insulin-like and insulin-antagonistic effects on glucose metabolism. To test whether leptin interferes directly with insulin signaling, we perfused isolated rat livers with leptin (0.1, 0.5, 5, and 25 nmol/liter), leptin + insulin (5 nmol/liter + 10 nmol/liter)
Konrad J Werhahn et al.
Epilepsia, 56(3), 450-459 (2015-02-17)
To compare the effectiveness of controlled-released carbamazepine (CR-CBZ) to levetiracetam (LEV) and to lamotrigine (LTG) in elderly patients with newly diagnosed focal epilepsy. Randomized, double-blind, parallel-group trial conducted between January 2007 and August 2011, in 47 ambulatory or hospital sites
D G Gascoyne et al.
The Journal of organic chemistry, 66(9), 3041-3048 (2001-04-28)
2,3-Dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol, 1, is a chiral bisphenol useful for preparation of polymers. Previous screening of commercial hydrolases identified lipase from Chromobacterium viscosum (CVL) as a highly regio- and enantioselective catalyst for hydrolysis of diesters of 1. The regioselectivity was > or
Karen M Edmond et al.
Lancet (London, England), 385(9975), 1315-1323 (2014-12-17)
Results of randomised controlled trials of newborn (age 1-3 days) vitamin A supplementation have been inconclusive. The WHO is coordinating three large randomised trials in Ghana, India, and Tanzania (Neovita trials). We present the findings of the Neovita trial in
N Yu et al.
Molecular biology and evolution, 18(2), 214-222 (2001-02-07)
Human DNA variation is currently a subject of intense research because of its importance for studying human origins, evolution, and demographic history and for association studies of complex diseases. A approximately 10-kb region on chromosome 1, which contains only four
Philipp Zanger et al.
The Lancet. Infectious diseases, 13(11), 946-954 (2013-09-10)
Travellers' diarrhoea causes substantial acute and long-term morbidity. Chemoprophylaxis with fluoroquinolones or rifaximin is effective in prevention of diarrhoea in individuals travelling to Latin America and Africa. Little evidence is available to support the protective effect of antimicrobial drugs in
Emanuel R Tenorio et al.
Journal of vascular surgery, 71(6), 1982-1993 (2019-10-16)
The objective of this study was to analyze the utility of cone beam computed tomography (CBCT) for technical assessment of standard and complex endovascular aneurysm repair (EVAR). Data of consecutive patients who underwent standard or complex EVAR in 2016 and
Katerina Theodoridou et al.
Journal of agricultural and food chemistry, 63(22), 5476-5484 (2015-05-23)
Recently, new lines of yellow-seeded (CS-Y) and black-seeded canola (CS-B) have been developed with chemical and structural alteration through modern breeding technology. However, no systematic study was found on the bioactive compounds, chemical functional groups, fatty acid profiles, inherent structure
Patrizia Natale et al.
The Cochrane database of systematic reviews, 6, CD013165-CD013165 (2020-06-27)
Hyperkalaemia is a common electrolyte abnormality caused by reduced renal potassium excretion in patients with chronic kidney diseases (CKD). Potassium binders, such as sodium polystyrene sulfonate and calcium polystyrene sulfonate, are widely used but may lead to constipation and other
1/1