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显示 1-30 共 49 条结果 关于 "123-19-3" 范围 论文
Irina Esterlis et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(1), 78-82 (2012-11-20)
In vivo estimation of β(2)-nicotinic acetylcholine receptor availability with molecular neuroimaging is complicated by competition between the endogenous neurotransmitter acetylcholine and the radioligand (123)I-3-[2(S)-2-azetidinylmethoxy]pyridine ((123)I-5-IA). We examined whether binding of (123)I-5-IA is sensitive to increases in extracellular levels of acetylcholine
Camilla Schalin-Jäntti et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(5), 739-747 (2013-04-05)
All patients with primary hyperparathyroidism should undergo localization studies before reoperation, but it is not known which method is most accurate. The purpose of this prospective study was to compare the performance of planar scintigraphy with (123)I/(99m)Tc-sestamibi, (99m)Tc-sestamibi SPECT (SPECT/CT)
Michele Ragno et al.
Stroke, 44(4), 1147-1149 (2013-02-16)
To describe parkinsonism as a clinical manifestation of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. We report 5 patients carrying the R1006C mutation in the exon 19 of NOTCH3 gene. All cases presented late onset, slowly progressive parkinsonism
Alex Iranzo et al.
The Lancet. Neurology, 10(9), 797-805 (2011-08-02)
Serial dopamine transporter (DAT) imaging in patients with Parkinson's disease (PD) and other synucleinopathies shows progressive nigrostriatal dopaminergic dysfunction. Because idiopathic rapid-eye-movement (REM) sleep behaviour disorder (IRBD) can precede the classic symptoms of PD and other synucleinopathies, we postulated that
Clemens Gutmann et al.
Nature communications, 12(1), 3406-3406 (2021-06-09)
Prognostic characteristics inform risk stratification in intensive care unit (ICU) patients with coronavirus disease 2019 (COVID-19). We obtained blood samples (n = 474) from hospitalized COVID-19 patients (n = 123), non-COVID-19 ICU sepsis patients (n = 25) and healthy controls (n = 30). Severe acute respiratory syndrome coronavirus
Jong-Min Kim et al.
Archives of neurology, 64(10), 1510-1518 (2007-10-10)
To examine the presence of an ATXN2 mutation in patients with parkinsonism in the Korean population and to find the difference in the ATXN2 mutation between ataxic and parkinsonian phenotypes. Survey. Seoul National University Hospital (a referral center). Patients Patients
Dorian R A Swarts et al.
The American journal of surgical pathology, 38(10), 1429-1436 (2014-07-22)
Pulmonary carcinoids are neuroendocrine tumors histopathologically subclassified into typical (TC; no necrosis, <2 mitoses per 2 mm) and atypical (AC; necrosis or 2 to 10 mitoses per 2 mm). The reproducibility of lung carcinoid classification, however, has not been extensively
Chun-Ying Ku et al.
Biology of reproduction, 67(2), 605-609 (2002-07-24)
The presence of cAMP-dependent protein kinase (PKA) in the plasma membrane compartment and its association with an A-kinase anchoring protein (AKAP150) is implicated in mediating cAMP regulatory events in the rat myometrium. The association of PKA with purified myometrial plasma
Douglas V Laurents et al.
Biopolymers, 91(12), 1018-1028 (2009-02-04)
Eosinophil cationic protein (ECP)/human RNase 3, a member of the RNase A family, is a remarkably cytotoxic protein implicated in asthma and allergies. These activities are probably due to ECP's ability to interact with and disrupt membranes and depend on
G Schmitz et al.
Nuklearmedizin. Nuclear medicine, 44(3), 86-93 (2005-06-22)
Molecular analysis of the expression of the sodium iodide symporter (NIS) in 32 patients with differentiated thyroid cancer (DTC) and correlation with scintigraphic findings ((131)I,(123)I) in 19 (59.4%) of them. NIS expression of 27 primary tumours, 13 lymphnodes and 18
B Babbette D LaMarca et al.
Hypertension (Dallas, Tex. : 1979), 46(4), 1022-1025 (2005-09-08)
Inflammatory cytokines such as tumor necrosis factor (TNF)-alpha are elevated in preeclamptic women and are thought to be an important link between placental ischemia and endothelial dysfunction. The purpose of this study was to determine the role of TNF in
P Gaye et al.
Biochimie, 69(6-7), 601-608 (1987-06-01)
The nucleotide sequence of ovine alpha-lactalbumin mRNA has been determined by chemical sequencing of two cDNA recombinant plasmids and a primer extension product. Ovine alpha-lactalbumin mRNA contains 723 nucleotides (excluding the poly(A) tail), with a 5' non-coding region of 26
H Zhang et al.
British journal of clinical pharmacology, 43(3), 245-252 (1997-03-01)
Our previous studies using in vitro hepatic microsomal preparations suggested that the hepatic metabolism of quinine to form the major metabolite 3-hydroxyquinine is most likely catalysed by human P450 3A (CYP3A). The present study was carried out to investigate the
Kwan-Yeung Wong et al.
British journal of haematology, 154(5), 569-578 (2011-06-29)
Epigenetic inactivation of tumour suppressor microRNAs has been implicated in carcinogenesis. We studied the promoter methylation of MIR203 in eight normal marrow controls, eight multiple myeloma (MM) cell lines, 20 monoclonal gammopathy of undetermined significance (MGUS), 123 diagnostic MM and
David Mischoulon et al.
The Journal of clinical psychiatry, 70(12), 1636-1644 (2009-08-28)
To examine the efficacy and tolerability of ethyl-eicosapentaenoate (EPA-E) monotherapy for major depressive disorder (MDD). Fifty-seven adults with DSM-IV MDD were randomly assigned from January 2003 until June 2006 to receive 1 g/d of eicosapentaenoic acid (EPA) or placebo for
Ravi K Murthy et al.
Cutaneous and ocular toxicology, 33(2), 132-137 (2013-07-19)
Lutein (LUT) and zeaxanthin (ZEA) are currently under investigation in clinical trials as prophylactic nutritional agents for age-related macular degeneration (AMD). However, dose used in these trials is empirical and not been investigated in in vitro studies. In this study
John R Atack et al.
The Journal of pharmacology and experimental therapeutics, 332(1), 17-25 (2009-09-26)
The GABA(A) receptor alpha2/alpha3 subtype-selective compound 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023; also known as MK-0777) is a triazolopyridazine that has similar, subnanomolar affinity for the benzodiazepine binding site of alpha1-, alpha2-, alpha3-, and alpha5-containing GABA(A) receptors and has partial agonist efficacy at the
K Sakai et al.
Human molecular genetics, 10(13), 1379-1386 (2001-07-07)
Autoimmune thyroid disease (AITD), including Graves' disease (GD) and Hashimoto's thyroiditis (HT), is caused by multiple genetic and environmental factors. The clinical and immunological features of GD and HT are distinct; however, there are multiplex families with both GD and
L N Nejsum et al.
American journal of physiology. Renal physiology, 280(4), F715-F726 (2001-03-16)
Diabetes mellitus (DM) is associated with osmotic diuresis and natriuresis. At day 15, rats with DM induced by streptozotocin (n = 13) had severe hyperglycemia (27.1 +/- 0.4 vs. 4.7 +/- 0.1 mM in controls) and had a fivefold increase
Tara-Jane Browne et al.
Human pathology, 35(12), 1462-1468 (2004-12-25)
Distinguishing benign prostate glands from malignant ones, based purely on morphology, on prostatic core needle biopsy specimens (PNBs) may prove difficult, particularly if the suspicious focus is small. In recent years, several immunohistochemical markers, including the basal cell cocktail (BCC)
Stephen H Gillespie et al.
The New England journal of medicine, 371(17), 1577-1587 (2014-09-10)
Early-phase and preclinical studies suggest that moxifloxacin-containing regimens could allow for effective 4-month treatment of uncomplicated, smear-positive pulmonary tuberculosis. We conducted a randomized, double-blind, placebo-controlled, phase 3 trial to test the noninferiority of two moxifloxacin-containing regimens as compared with a
M L Koschinsky et al.
Proceedings of the National Academy of Sciences of the United States of America, 83(14), 5086-5090 (1986-07-01)
A cDNA for human ceruloplasmin (EC 1.16.3.1) was identified in a human liver cDNA library by screening with two mixtures of synthetic oligodeoxyribonucleotides that were complementary to two regions of ceruloplasmin mRNA as predicted from the amino acid sequence of
Song-Yu Yang et al.
BMC biochemistry, 14, 17-17 (2013-07-10)
Hydroxysteroid (17beta) dehydrogenase X (HSD10) is a multifunctional protein encoded by the HSD17B10 gene at Xp11.2. In response to stress or hypoxia-ischemia its levels increase rapidly. Expression of this gene is also elevated significantly in colonic mucosa of the inactive
Martin Gevonden et al.
JAMA psychiatry, 71(12), 1364-1372 (2014-10-02)
An increased risk for psychosis is observed in people with hearing impairment. According to the social defeat hypothesis, the long-term experience of exclusion leads to enhanced baseline activity and/or sensitization of the dopamine system and puts the individual at increased
V Polanská et al.
Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 64(2), 77-80 (2008-04-19)
The aim of this study was to evaluate the presence of the dry eye syndrome and corneal complications in patients with rheumatoid arthritis and to assess its association with the -174 gene polymorphism for interleukin 6. The group consisted of
Jessica L Faulkner et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 310(4), R346-R354 (2015-12-18)
Deficiency of vitamin D (VD) is associated with preeclampsia (PE), a hypertensive disorder of pregnancy characterized by proinflammatory immune activation. We sought to determine whether VD supplementation would reduce the pathophysiology and hypertension associated with the reduced uterine perfusion pressure
Erdem Cevik et al.
The American journal of emergency medicine, 30(8), 1486-1490 (2012-02-07)
The aim of this study was to compare the efficacy and safety of 3 nonsteroidal anti-inflammatory drugs-intravenous tenoxicam, lornoxicam, and dexketoprofen trometamol-for the treatment of patients with renal colic. We conducted a prospective double-blind randomized trial of consecutive adult patients
Yan-yan Zhao et al.
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 46(12), 1066-1070 (2011-01-08)
To analyze the relationship between the gene polymorphism of IL-2R (rs2104286) and IL-7R (rs6897932) and the susceptibility to idiopathic demyelinating optic neuritis (IDON). A case-control study was performed in 72 IDON patients and 81 healthy individuals as the control group.
Mathieu Manassero et al.
Journal of feline medicine and surgery, 16(8), 623-630 (2013-12-07)
Ureteral obstruction secondary to ureterolithiasis in cats is a challenging situation. Ureteral stenting has recently been introduced to prevent complications that often occurred after ureterotomy or other invasive surgeries. The purpose of this study is to describe the stenting technique
Sylvie Slaets et al.
International journal of geriatric psychiatry, 30(8), 864-869 (2014-11-05)
Iodine-123 metaiodobenzylguanidine (MIBG) cardiac scintigraphy has shown the potential to discriminate dementia with Lewy bodies (DLB) from Alzheimer's disease (AD). However, these studies did not reflect clinical practice, as patients with ischemic heart disease, heart failure, diabetes mellitus, arterial hypertension
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