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关键词:'126-72-7'
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National Toxicology Program technical report series, (531)(531), 1-218 (2007-03-08)
DIOXIN TOXIC EQUIVALENCY FACTOR EVALUATION OVERVIEW: Polyhalogenated aromatic hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) have the ability to bind to and activate the ligand-activated transcription factor, the aryl hydrocarbon receptor (AhR). Structurally related compounds that bind to the AhR and exhibit
Robert Grützmann et al.
PloS one, 3(11), e3759-e3759 (2008-11-20)
Colorectal cancer (CRC) is the second leading cause of cancer deaths despite the fact that detection of this cancer in early stages results in over 90% survival rate. Currently less than 45% of at-risk individuals in the US are screened
Chun-Hua Hang et al.
World journal of gastroenterology, 10(6), 875-880 (2004-03-25)
To study the alterations of brain-gut peptides following traumatic brain injury (TBI) and to explore the underlying significance of these peptides in the complicated gastrointestinal dysfunction. Rat models of focal traumatic brain injury were established by impact insult method, and
N Goldaracena et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 14(12), 2788-2795 (2014-10-04)
Outcomes of living versus deceased donor liver transplantation in patients with chronic liver disease and hepatorenal syndrome (HRS) was compared using a matched pair study design. Thirty patients with HRS receiving a live donor liver transplantation (LDLT) and 90 HRS
Angela Seeringer et al.
European journal of clinical pharmacology, 64(9), 883-888 (2008-06-12)
Our objective was to study the enantioselective pharmacokinetics of metoprolol in CYP2D6 ultra-rapid metabolizers (UM) compared with extensive (EM) and poor (PM) metabolizers to quantify differential effects of metoprolol enantiomers on the beta1-adrenoreceptor blockade. Twenty-nine healthy individuals were selected based
Inga Gurevich et al.
American journal of clinical pathology, 135(3), 398-403 (2011-02-26)
Refractory anemia with ring sideroblasts associated with marked thrombocytosis (RARS-T) is a provisional entity in the current World Health Organization classification and is thought to be a myelodysplastic/myeloproliferative neoplasm (MDS/MPN). We analyzed 18 cases of RARS-T. All patients had thrombocytosis
Rosane Vianna-Jorge et al.
Clinical pharmacology and therapeutics, 76(1), 18-26 (2004-07-02)
Cytochrome P450 (CYP) 2C9, the product of the polymorphic gene CYP2C9, provides the major catabolic pathway for several anti-inflammatory drugs, including tenoxicam. Our objectives were (1) to determine the frequency of 2 common CYP2C9 variant alleles (*2 and *3) in
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