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Anders Bach et al.
Scientific reports, 5, 12157-12157 (2015-07-17)
ZL006 and IC87201 have been presented as efficient inhibitors of the nNOS/PSD-95 protein-protein interaction and shown great promise in cellular experiments and animal models of ischemic stroke and pain. Here, we investigate the proposed mechanism of action of ZL006 and
Krisztina Sebok-Nagy et al.
Photochemistry and photobiology, 81(5), 1212-1218 (2005-05-20)
The fluorescent properties of 2-hydroxy Nile red dye (HONR) proved to be highly sensitive to the basicity of hydrogen bond acceptors. Fluorescence quantum yields and fluorescence decay profiles were measured as the function of the concentration of organic nitrogen compounds
Halogen complexes. III. The association of 2, 4, 6-trimethylpyridine and trifluoroiodomethane.
Larsen DW and Allred AL.
The Journal of Physical Chemistry, 69(7), 2400-2401 (1965)
Christa A Currie et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 824(1-2), 201-205 (2005-08-09)
Microchip capillary electrophoresis (CE), coupled with indirect fluorescence detection was investigated for estimating the pK(a) values of non-fluorescent compounds. The CE method is based on the differences in electrophoretic mobility of the analyte as a function of the pH of
J L Tomsig et al.
Histochemistry, 87(1), 21-25 (1987-01-01)
Rat pineal nerve endings contain a population of small and of large synaptic vesicles that are either electron lucent or have electron-dense cores. It has been reported that their osmiophilia is eliminated when collidine buffer is used in the fixation
zeta-Collidine as a basis for buffering fixatives.
H S BENNETT et al.
The Journal of biophysical and biochemical cytology, 6(1), 113-114 (1959-08-01)
J Hasegawa et al.
Journal of pharmaceutical sciences, 73(4), 442-445 (1984-04-01)
The pKa of verapamil was determined by measuring the partition coefficient of verapamil between n-heptane and aqueous buffer solution at various pH values. The magnitude of the effects of ionic strength or temperature on the pKa of verapamil was in
Synthesis, structure, photoluminescence and magnetic properties of new 3-D lanthanide-pyridine-2, 4, 6-tricarboxylate frameworks
Li C-J, et al.
CrystEngComm, 10(11), 1645-1652 (2008)
Jae H Park et al.
Journal of medicinal chemistry, 57(15), 6623-6631 (2014-07-16)
The aqueous solution structure of protoxin II (ProTx II) indicated that the toxin comprises a well-defined inhibitor cystine knot (ICK) backbone region and a flexible C-terminal tail region, similar to previously described NaSpTx III tarantula toxins. In the present study
Possible involvement of Na+,K(+)-ATPase inhibition in neurotransmitter release induced by collidine.
G Rodríguez de Lores Arnaiz et al.
Neuroscience letters, 108(3), 309-313 (1990-01-22)
Previous histochemical studies have demonstrated that collidine abolished the osmiophilia and the chromaffin reaction of the synaptic vesicles, an effect which was ascribed to the release of stored neurotransmitters. Other studies indicated a relationship between the inhibition of Na+,K(+)-ATPase and
Michael Wleklinski et al.
Physical chemistry chemical physics : PCCP, 17(28), 18364-18373 (2015-06-25)
Electrospray ionization of metal salt solutions followed by ambient heating transforms the resulting salt clusters into new species, primarily naked ionic metal clusters. The experiment is done by passing the clusters through a heated coiled loop outside the mass spectrometer
Tatsuki Nakano et al.
Analytica chimica acta, 880, 145-151 (2015-06-21)
In this study, a novel pre-column excimer fluorescence derivatization reagent, 2-chloro-4-methoxy-6-(4-(pyren-4-yl)butoxy)-1,3,5-triazine (CMPT), was developed for polyamines, specifically histamine. By CMPT derivatization, the polyamines, histamine and tyramine were converted to polypyrene derivatives, and emitted intra-molecular excimer fluorescence at 475nm. This could
Jeffrey R Kanofsky et al.
Journal of photochemistry and photobiology. B, Biology, 87(2), 124-129 (2007-04-25)
Prior work using cell culture has shown that certain synthetic carotenoid derivatives are more effective than natural carotenoids in preventing photosensitized cell killing. These carotenoid derivatives are either cationic or are weak bases. We have now found that of one
E Oforah et al.
Pharmacology, 27(3), 176-179 (1983-01-01)
The metabolic oxidation of chlorpromazine (CPZ) was investigated after pretreatment of rats with some drugs and chemicals for 6 days. Pentobarbitone, gamma-collidine, ethanol, and anthracene induced a significant increase in both S-oxidation and 7-hydroxylation, whereas CPZ pretreatment increased mainly 7-hydroxylation.
Sumanta Bhattacharya et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 58(12), 2563-2569 (2002-10-25)
[60]fullerene has been shown to form 1:1 molecular complexes with pyridine and some methylated pyridines such as 2-picoline, 3-picoline, 4-picoline, 2,6-lutidine and 2,4,6-collidine in CCl4 medium by absorption spectrometric method. Well defined charge transfer (CT) bands have been observed for
Andrew W Patterson et al.
Nature protocols, 2(2), 424-433 (2007-04-05)
Substrate activity screening (SAS) is a fragment-based method for the rapid development of novel substrates and their conversion into non-peptidic inhibitors of Cys and Ser proteases. The method consists of three steps: (i) a library of N-acyl aminocoumarins with diverse
Stephen M Baumler et al.
Journal of electroanalytical chemistry (Lausanne, Switzerland), 812, 159-165 (2018-03-06)
Understanding the thermodynamics and kinetics of interactions between model lipid bilayers and planar supports is of critical importance in the furtherance of biosensing and the creation of biomimetic devices. Evaluating these properties can be accomplished through understanding the diffusional properties
W G Dauben et al.
Carbohydrate research, 203(1), 47-56 (1990-08-01)
The yields of disaccharide glycosylation products in tetramethylammonium bromide or silver triflate-collidine activated reactions between hindered alcohols and glycosyl halides were not greatly ++affected when a pressure of 15 kbar was applied. The formation of orthoester products was greatly increased
Werner J Geldenhuys et al.
Bioorganic & medicinal chemistry letters, 20(16), 4870-4877 (2010-07-20)
The high affinity neuronal choline transporter (CHT1) is responsible for the uptake of choline into the pre-synaptic terminal of cholinergic neurons. Considering our past experience with modeling the blood-brain barrier choline transporter (BBBCHT) as drug delivery vector to the CNS
Hiromichi Fujioka et al.
Chemistry, an Asian journal, 7(2), 367-373 (2011-12-14)
Mild substitution reactions of acetals with carbon nucleophiles via the pyridinium-type salts generated by the treatment of acetals with TESOTf-2,4,6-collidine or 2,2'-bipyridyl have been developed. Various carbon nucleophiles, such as organocuprates, silyl enol ethers, enamines, etc., reacted with the pyridinium-type
Maria Stella Ritorto et al.
Nature communications, 5, 4763-4763 (2014-08-28)
Deubiquitylases (DUBs) are key regulators of the ubiquitin system which cleave ubiquitin moieties from proteins and polyubiquitin chains. Several DUBs have been implicated in various diseases and are attractive drug targets. We have developed a sensitive and fast assay to
A Pellegrino de Iraldi et al.
Histochemistry, 101(6), 419-425 (1994-07-01)
In previous work of our laboratory, it was demonstrated that collidine (2-4-6-trimethylpyridine) applied briefly to fresh tissues extracted noradrenaline or closely related compound/s of neuronal origin. This effect gave rise to the abolition of osmiophilia and chromaffin reaction of electron-dense
Masayoshi Tsubuki et al.
The Journal of organic chemistry, 74(3), 1422-1425 (2008-12-20)
We have found that ruthenium-catalyzed cyclocarbonylation of allenyl alcohols in 2,4,6-collidine under atmospheric pressure of carbon monoxide smoothly proceeds to afford alpha,beta-unsaturated five- and six-membered lactones in moderate to good yields. Furthermore, we have completed a highly stereoselective synthesis of
Leszek Pazderski et al.
Magnetic resonance in chemistry : MRC, 48(6), 417-426 (2010-05-18)
(1)H, (13)C and (15)N NMR studies of gold(III), palladium(II) and platinum(II) chloride complexes with dimethylpyridines (lutidines: 2,3-lutidine, 2,3lut; 2,4-lutidine, 2,4lut; 3,5-lutidine, 3,5lut; 2,6-lutidine, 2,6lut) and 2,4,6-trimethylpyridine (2,4,6-collidine, 2,4,6col) having general formulae [AuLCl(3)], trans-[PdL(2)Cl(2)] and trans-/cis-[PtL(2)Cl(2)] were performed and the respective
J L Tomsig et al.
Histochemistry, 89(3), 301-306 (1988-01-01)
In previous work of our laboratory it was demonstrated that collidine (2,4,6-trimethylpyridine) abolishes the core osmiophilia and chromaffin reaction from rat pinal gland and vas deferens nerves. This abolition was apparent when tissues were briefly incubated in collidine or when
Janet E Del Bene et al.
The journal of physical chemistry. A, 110(3), 1128-1133 (2006-01-20)
Ab initio EOM-CCSD calculations have been performed on 3:1 FH:NH3 complexes at their own optimized MP2/6-31+G(d,p) geometries and at the optimized geometries in the hydrogen-bonding regions of corresponding 3:1 FH:collidine complexes. The isolated gas-phase equilibrium 3:1 FH:NH3 complex has an
Lilas Hadji et al.
PloS one, 9(8), e106214-e106214 (2014-08-30)
Adipocyte size and body fat distribution are strongly linked to the metabolic complications of obesity. The aim of the present study was to test the plasticity of white adipose tissue in response to insulin deprivation and replacement. We have characterized
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