1600-86-5

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High BRE expression predicts favorable outcome in adult acute myeloid leukemia, in particular among MLL-AF9-positive patients.

Sylvie M Noordermeer et al.

Blood, 118(20), 5613-5621 (2011-09-23)

Aberrations in protein ubiquitination have recently been identified in the pathogenesis of acute myeloid leukemia (AML). We studied whether expression changes of more than 1600 ubiquitination related genes correlated with clinical outcome in 525 adult AML patients. High expression of

High molecular weight insulin-like growth factor binding protein complex. Purification and properties of the acid-labile subunit from human serum.

R C Baxter et al.

The Journal of biological chemistry, 264(20), 11843-11848 (1989-07-15)

In the human circulation, the insulin-like growth factors (IGFs) circulate as part of a growth hormone-dependent 125- to 150-kDa complex. This complex has been postulated to contain, in addition to IGFs and one or more IGF-binding proteins, an acid-labile subunit

Diet-induced obesity associated with steatosis, oxidative stress, and inflammation in liver.

Yanhua Peng et al.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 8(1), 73-81 (2011-10-08)

Obesity induces steatosis and increases oxidative stress, as well as chronic inflammation in the liver. The balance between lipogenesis and lipolysis is disrupted in obese animals. At a cellular level, the changes in metabolic sensors and energy regulators are poorly

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