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Xun Hu et al.
Bioresource technology, 102(21), 10104-10113 (2011-09-13)
The formation of humin-type polymers and other products during exposure of glucose to methanol/water mixtures with methanol/water mass ratios from 10 to 0.22 in the presence of the acid catalyst Amberlyst 70 was investigated. In water-rich medium (methanol/water mass ratio:
N Villota et al.
Environmental science and pollution research international, 24(2), 1105-1112 (2016-07-29)
This paper deals with the changes of turbidity that are generated in aqueous solutions of phenol when they are oxidized by using different Fenton technologies. Results revealed that if the Fenton reaction was promoted with UV light, the turbidity that
Yan Wang et al.
Environmental toxicology, 29(12), 1437-1451 (2013-06-19)
Benzene-induced erythropoietic depression has been proposed to be due to the production of toxic metabolites. Presently, the cytotoxicities of benzene metabolites, including phenol, catechol, hydroquinone, and 1,2,4-benzenetriol, to erythroid progenitor-like K562 cells were investigated. After exposure to these metabolites, K562
Xiao-Rong Wu et al.
Toxicology letters, 203(3), 190-199 (2011-03-19)
Benzene is a common occupational hazard and a ubiquitous environmental pollutant. Benzene exposure at the levels even below 1ppm still showed hematotoxicity. It is widely accepted that the metabolites of benzene play important roles in the benzene toxicity to the
Kenta Yamamoto et al.
Journal of bioscience and bioengineering, 111(6), 687-694 (2011-03-15)
4-Nitrophenol (4-NP) is a toxic compound formed in soil by the hydrolysis of organophosphorous pesticides, such as parathion. We previously reported the presence of the 4-NP degradation gene cluster (nphRA1A2) in Rhodococcus sp. strain PN1, which encodes a two-component 4-NP
Kiwan Kim et al.
Microbial pathogenesis, 49(4), 174-180 (2010-07-03)
We have previously shown that PQS and HHQ, two quorum sensing molecules, can down-regulate host the innate immune responses and that this is mediated through the NF-kappaB pathway. In this study, to search for a comprehensive set of genes regulated
Hiroshi Kimura et al.
The journal of physical chemistry. A, 117(10), 2102-2113 (2013-03-06)
Noncatalytic reactions of D-fructose were kinetically investigated in dimethylsulfoxide (DMSO), water, and methanol as a function of time at temperatures of 30-150 °C by applying in situ (13)C NMR spectroscopy. The products were quantitatively analyzed with distinction of isomeric species
Luoping Zhang et al.
Environmental and molecular mutagenesis, 45(4), 388-396 (2005-01-22)
The loss and gain of whole chromosomes (aneuploidy) is common in the development of leukemia and other cancers. In acute myeloid leukemia, the loss (monosomy) of chromosomes 5 and 7 and the gain (trisomy) of chromosome 8 are common clonal
Atsushi Suzuki et al.
FEBS letters, 580(9), 2317-2322 (2006-04-04)
Chlorogenic acid, a polyphenol found in coffee, has antihypertensive actions, but epidemiologic data on the effects of coffee on blood pressure are controversial. Specific coffee components that inhibit the hypotensive effect of chlorogenic acid and the physiologic mechanisms underlying the
Matthias Boll
Journal of molecular microbiology and biotechnology, 10(2-4), 132-142 (2006-04-29)
The high resonance energy of the benzene ring is responsible for the relative resistance of aromatic compounds to biodegradation. Nevertheless, bacteria from nearly all physiological groups have been isolated which utilize aromatic growth substrates as the sole source of cell
Bruce Gillis et al.
Genomics, 90(3), 324-333 (2007-06-19)
Benzene is a common air pollutant and confirmed carcinogen, especially in reference to the hematopoietic system. In the present study we analyzed cytokine/chemokine production by, and gene expression induction in, human peripheral blood mononuclear cells upon their exposure to the
Ryuji Ochiai et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 32(11), 969-974 (2009-08-29)
Recent studies suggest that chlorogenic acids, which are the main components of the polyphenol class in coffee, decrease blood pressure, and that hydroxyhydroquinone (HHQ), which is generated by roasting coffee beans, inhibits the antihypertensive effect of chlorogenic acids in brewed
DNA breakage induced by 1, 2, 4-benzenetriol: relative contributions of oxygen-derived active species and transition metal ions
Li AS, et al.
Free Radical Biology & Medicine, 30(9), 943-956 (2001)
Zbigniew Srokol et al.
Carbohydrate research, 339(10), 1717-1726 (2004-06-29)
During the hydrothermal upgrading of biomass, hydrolysis to glucose is an important step. To elucidate some of the reaction pathways that follow this initial hydrolysis, the hydrothermal treatment (340 degrees C, 27.5 MPa, 25-204 s) of dilute (50 mM) solutions
Atsushi Suzuki et al.
American journal of hypertension, 20(5), 508-513 (2007-05-09)
Ferulic acid (FA), a phytochemical constituent, has antihypertensive effects, but a detailed understanding of its effects on vascular function remains unclear. The vasoreactivity of FA was assessed using aortic rings isolated from normotensive Wistar Kyoto (WKY) and spontaneously hypertensive rats
Tohru Yamaguchi et al.
Nutrition, metabolism, and cardiovascular diseases : NMCD, 18(6), 408-414 (2007-10-24)
Coffee is rich in chlorogenic acids (CGA), whose metabolites may have beneficial effects such as anti-hypertensive effects. However, trial results concerning the effects of coffee on blood pressure (BP) are not consistent. A recent study suggested that hydroxyhydroquinone (HHQ), produced
Zhenchun Sun et al.
Food chemistry, 322, 126754-126754 (2020-04-14)
During storage of coffee, the key aroma 2-furfurylthiol becomes less active, the mechanisms of this loss and ways to mitigate it were investigated. Aroma profiles were analyzed using GC-MS and sensory properties were evaluated by Quantitative Descriptive Analysis. Quinones, as
Takuro Nishikawa et al.
Environmental health perspectives, 120(1), 62-67 (2011-08-24)
Although benzene is known to be myelotoxic and to cause myeloid leukemia in humans, the mechanism has not been elucidated. We focused on 1,2,4-benzenetriol (BT), a benzene metabolite that generates reactive oxygen species (ROS) by autoxidation, to investigate the toxicity
Lyndon M West et al.
Journal of natural products, 71(2), 269-271 (2008-02-09)
The marine sponge Acanthodendrilla sp. contains the proteasome inhibitor acanthosulfate ( 4), a disulfated merosesterterpene having a scalarane-type skeleton. The structure of acanthosulfate ( 4), which possesses an unusual configuration, was elucidated by interpretation of spectroscopic data.
Karolina Nordin et al.
Applied and environmental microbiology, 71(11), 6538-6544 (2005-11-05)
Arthrobacter chlorophenolicus A6, a previously described 4-chlorophenol-degrading strain, was found to degrade 4-chlorophenol via hydroxyquinol, which is a novel route for aerobic microbial degradation of this compound. In addition, 10 open reading frames exhibiting sequence similarity to genes encoding enzymes
Samia Ammar et al.
Chemical & pharmaceutical bulletin, 55(3), 385-388 (2007-03-03)
A new skeleton of an O-heteroside natural substance named zinolol, the first representative of a new class of aminated hydroxyhydroquinone, has been isolated from the whole plant Anagallis monelli. Its structure has been established by one and two dimensional NMR
Rolis Chien-Wei Hou et al.
Journal of biomedical science, 13(1), 89-99 (2005-11-26)
Hydroxyhydroquinone or 1,2,4-benzenetriol (BT) detected in the beverages has a structure that coincides with the water-soluble form of a sesame lignan, sesamol. We previously showed that sesame antioxidants had neuroprotective abilities due to their antioxidant properties and/or inducible nitric oxide
Shosuke Ito et al.
Journal of dermatological science, 80(1), 18-24 (2015-08-01)
Tyrosinase is able to oxidize a great number of phenols and catechols to form ortho-quinones. Ortho-quinones are highly reactive compounds that exert cytotoxicity through binding with thiol enzymes and the production of reactive oxygen species. Certain phenolic (and catecholic) compounds
Kingo Suzuki et al.
International immunopharmacology, 10(11), 1448-1455 (2010-09-15)
Pyrogallol-bearing polyphenolic compounds induce spreading of polymorphonuclear leukocytes (PMNL), although their optimal concentrations for induction of spreading are quite different (2000, 200, and 2 μM for pyrogallol, (-)-epigallocatechin gallate (EGCG), and tannic acid (TA), respectively), and TA tends to inhibit
Min Wei et al.
Biodegradation, 21(6), 915-921 (2010-04-03)
Pseudomonas sp. strain WBC-3 utilizes para-nitrophenol (PNP) as a sole source of carbon, nitrogen and energy. PnpA (PNP 4-monooxygenase) and PnpB (para-benzoquinone reductase) were shown to be involved in the initial steps of PNP catabolism via hydroquinone. We demonstrated here
Massimo Moretti et al.
Toxicology letters, 157(2), 119-128 (2005-04-20)
In the present study, we investigated in vitro the possible genotoxic and/or co-genotoxic activity of 50 Hz (power frequency) magnetic fields (MF) by using the alkaline single-cell microgel-electrophoresis (comet) assay. Sets of experiments were performed to evaluate the possible interaction
Paula I Darley et al.
Journal of bacteriology, 189(10), 3824-3833 (2007-03-21)
Azoarcus anaerobius, a strictly anaerobic, gram-negative bacterium, utilizes resorcinol as a sole carbon and energy source with nitrate as an electron acceptor. Previously, we showed that resorcinol degradation by this bacterium is initiated by two oxidative steps, both catalyzed by
Vasili M Travkin et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 41(8), 1361-1382 (2006-11-09)
Several peripheral metabolic pathways can be used by microorganisms to degrade toxic aromatic compounds that are known to pollute the environment. Hydroxyquinol (1,2,4-trihydroxybenzene) is one of the central intermediates in the degradative pathway of a large variety of aromatic compounds.
Tang Li et al.
Applied and environmental microbiology, 78(17), 6009-6016 (2012-06-19)
The rol (designated for resorcinol) gene cluster rolRHMD is involved in resorcinol catabolism in Corynebacterium glutamicum, and RolR is the TetR-type regulator. In this study, we investigated how RolR regulated the transcription of the rol genes in C. glutamicum. The
Generation of hydrogen peroxide from hydroxyhydroquinone and its inhibition by superoxide dismutase
Hiramoto K, et al.
Journal of Oleo Science, 50(1), 21-28 (2001)
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