188204

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关键词:'188204'

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Medicinal Chemistry Research, 3, 192-192 (1993)

Tetrahedron Letters, 48, 5977-5977 (2006)

Synthesis of novel triplet drugs with 1,3,5-trioxazatriquinane skeletons and their pharmacologies. Part 2: Synthesis of novel triplet drugs with the epoxymethano structure (capped homotriplet).

Hiroshi Nagase et al.

Bioorganic & medicinal chemistry letters, 21(20), 6198-6202 (2011-09-06)

An improved synthetic method for triplet drugs with the 1,3,5-trioxazatriquinane skeleton was developed that used p-toluenesulfonylmethyl isocyanide (TosMIC) instead of 1,3-dithiane. Using the improved method, we synthesized compounds with two identical pharmacophore units and an epoxymethano group, that is, capped

Microwave-assisted synthesis of imidazoles: reaction of p-toluenesulfonylmethyl isocyanide and polymer-bound imines.

Swapan K Samanta et al.

Bioorganic & medicinal chemistry letters, 15(16), 3717-3719 (2005-07-05)

A convenient method for the synthesis of 1,5-disubstituted imidazoles has been developed on a polymeric support using base-promoted 1,3-dipolar cycloaddition reaction of p-toluenesulfonylmethyl isocyanide (TOSMIC) with immobilized imines under microwave irradiation. The immobilized imines were synthesized by the reaction of

Alkyl and aromatic isocyanide binding to haem complexes.

M J Patel et al.

The Biochemical journal, 262(3), 959-963 (1989-09-15)

Equilibrium constants for the binding of ethyl (EIC), n-butyl (BIC), p-toluenesulphonylmethyl (TMIC) and 2,6-dimethylphenyl isocyanides (DIMPI) to an imidazole-haem complex in toluene and aqueous detergent micelle solutions were determined. In contrast to an earlier study, which indicated that the large

Il Farmaco (Societa Chimica Italiana : 1989), 48, 209-209 (1993)

Exciton funneling in light-harvesting organic semiconductor microcrystals for wavelength-tunable lasers.

Kang Wang et al.

Science advances, 5(6), eaaw2953-eaaw2953 (2019-06-20)

Organic solid-state lasers are essential for various photonic applications, yet current-driven lasing remains a great challenge. Charge transfer (CT) complexes formed with p-/n-type organic semiconductors show great potential in electrically pumped lasers, but it is still difficult to achieve population

p-Toluenesulfonylmethyl Isocyanide: A Versatile Synthon in Organic Chemistry.

Tandon VK and Rai S.

Journal of Sulfur Chemistry, 24(3), 307-385 (2003)

Phenanthroline-bis-oxazole ligands for binding and stabilization of G-quadruplexes.

João Medeiros-Silva et al.

Biochimica et biophysica acta, 1861(5 Pt B), 1281-1292 (2016-11-21)

G-quadruplexes (G4) are found at important genome regions such as telomere ends and oncogene promoters. One prominent strategy to explore the therapeutic potential of G4 is stabilized it with specific ligands. We report the synthesis of new phenanthroline, phenyl and

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