200-786-7

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Nanoemulsion-templated multilayer nanocapsules for cyanine-type photosensitizer delivery to human breast carcinoma cells.

Urszula Bazylińska et al.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(2), 406-420 (2012-07-17)

There is great clinical interest in developing novel nanocarriers for hydrophobic cyanine dyes used as photosensitizing agents in photodynamic therapy (PDT). In the present study we have employed nanoemulsion-templated oil-core multilayer nanocapsules as robust nanocarriers for a cyanine-type photosensitizer IR-786.

Repurposing propranolol as an antitumor agent in von Hippel-Lindau disease.

Matthew J Shepard et al.

Journal of neurosurgery, 1-9 (2018-12-01)

OBJECTIVEVon Hippel-Lindau disease (VHL) is a tumor predisposition syndrome characterized by CNS hemangioblastomas (HBs) and clear cell renal cell carcinomas (RCCs) due to hypoxia-inducible factor activation (pseudohypoxia). Because of the lack of effective medical therapies for VHL, HBs and RCCs

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