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Alexandra Roşulescu et al.
Polish journal of pathology : official journal of the Polish Society of Pathologists, 71(3), 200-206 (2020-10-29)
Gastrointestinal stromal tumors (GISTs) are rare neoplasms, colorectal location being met in less than 5% of cases. Knowledge about this site related particularities are limited. The aim of this study is to present our experience with colorectal GISTs between 2005
Thibault Duburcq et al.
Shock (Augusta, Ga.), 52(4), e60-e67 (2018-10-17)
Antithrombin (AT) III physiological levels are decreased during septic shock and supplementation therapy could therefore be beneficial. We hypothesized that the use of recombinant human AT could reduce disseminated intravascular coagulation (DIC) occurrence. We conducted a randomized open label controlled
P Jeffrey et al.
The Journal of pharmacy and pharmacology, 43(10), 715-720 (1991-10-01)
The site of metabolic inversion of R(-)-ibuprofen to the pharmacologically active S(+)-enantiomer has been investigated using an array of in-situ rat perfused organ preparations allowing vascular perfusion (55-60 min) of the separate or combined intestine and liver. After addition of
L LeGros et al.
The Journal of biological chemistry, 276(27), 24918-24924 (2001-05-05)
Methionine adenosyltransferase (MAT) catalyzes the biosynthesis of S-adenosylmethionine (AdoMet), a key molecule in transmethylation reactions and polyamine biosynthesis. The MAT II isozyme consists of a catalytic alpha2 and a regulatory beta subunit. Down-regulation of the MAT II beta subunit expression
S Reich et al.
Blood, 96(10), 3357-3363 (2000-11-09)
The butyrate derivative isobutyramide (IBT) increases fetal hemoglobin (HbF) in patients with beta-hemoglobinopathies, but little is known about its usefulness for prolonged therapeutic use. We treated 8 patients with transfusion-dependent beta-thalassemia with 350 mg/kg of body weight per day of
Oluyemi Komolafe et al.
The Cochrane database of systematic reviews, 7, CD013157-CD013157 (2021-07-20)
The prevalence of non-alcohol-related fatty liver disease (NAFLD) varies between 19% and 33% in different populations. NAFLD decreases life expectancy and increases risks of liver cirrhosis, hepatocellular carcinoma, and the requirement for liver transplantation. Uncertainty surrounds relative benefits and harms
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