206-133-2

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Myogenic factors that regulate expression of muscle-specific microRNAs.

Prakash K Rao et al.

Proceedings of the National Academy of Sciences of the United States of America, 103(23), 8721-8726 (2006-05-30)

Since their discovery as key regulators of early animal development, microRNAs now are recognized as widespread regulators of gene expression. Despite their abundance, little is known regarding the regulation of microRNA biogenesis. We show that three highly conserved muscle-specific microRNAs

Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients.

Stefano Gambardella et al.

Journal of translational medicine, 8, 48-48 (2010-05-22)

MicroRNAs are highly conserved, noncoding RNAs involved in post-transcriptional gene silencing. They have been shown to participate in a wide range of biological processes, including myogenesis and muscle regeneration. The goal of this study is to test the hypothesis that

MicroRNA expression and protein acetylation pattern in respiratory and limb muscles of Parp-1(-/-) and Parp-2(-/-) mice with lung cancer cachexia.

Alba Chacon-Cabrera et al.

Biochimica et biophysica acta, 1850(12), 2530-2543 (2015-10-04)

Current treatment options for cachexia, which impairs disease prognosis, are limited. Muscle-enriched microRNAs and protein acetylation are involved in muscle wasting including lung cancer (LC) cachexia. Poly(ADP-ribose) polymerases (PARP) are involved in muscle metabolism. We hypothesized that muscle-enriched microRNA, protein

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