206-176-7

应用筛选条件

关键词:'206-176-7'

显示 1-1 共 1 条结果关于 "206-176-7" 范围论文

Haplotypes and a novel defective allele of CES2 found in a Japanese population.

Su-Ryang Kim et al.

Drug metabolism and disposition: the biological fate of chemicals, 35(10), 1865-1872 (2007-07-21)

Human carboxylesterase 2 (hCE-2) is a member of the serine esterase superfamily and is responsible for hydrolysis of a wide variety of xenobiotic and endogenous esters. hCE-2 also activates an anticancer drug, irinotecan (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin, CPT-11), into its active metabolite, 7-ethyl-10-hydroxycamptothecin

1/1