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显示 1-30 共 580 条结果 关于 "21049" 范围 论文
Tauseef M Asmat et al.
PloS one, 9(12), e114474-e114474 (2014-12-03)
The pili and outer membrane proteins of Neisseria meningitidis (meningococci) facilitate bacterial adhesion and invasion into host cells. In this context expression of meningococcal PilC1 protein has been reported to play a crucial role. Intracellular calcium mobilization has been implicated
Caterina Peraldo-Neia et al.
BMC cancer, 14, 918-918 (2014-12-07)
Standard chemotherapy in unresectable biliary tract carcinoma (BTC) patients is based on gemcitabine combined with platinum derivatives. However, primary or acquired resistance is inevitable and no second-line chemotherapy is demonstrated to be effective. Thus, there is an urgent need to
Livia C Natale et al.
Materials science & engineering. C, Materials for biological applications, 76, 464-471 (2017-05-10)
Silver phosphate is a semi-conductor sensitive to UV-Vis radiation (<530nm). Exposure to radiation removes electrons from the oxygen valence shell, which are scavenged by silver cations (Ag
E Bezati et al.
Lupus, 24(1), 32-41 (2014-08-21)
Quinine, a quinoline derivative, is an ancient antipyretic drug with antimalarial properties that has been phased out by more effective synthetic candidates. In previous studies we discovered that hydroxychloroquine (HCQ), a synthetic antimalarial with structural similarities to quinine, reduced the
Elisabeth Eschlbeck et al.
Journal of microbiological methods, 135, 1-7 (2017-01-31)
Contact angle measurement of microorganisms is often described in literature, either to investigate their hydrophobic characteristic or the adhesion behavior of cells. However, in some key aspects the preparation methods differ. Thus, it is difficult to compare results and to
Mohammad Mehdi Movahednia et al.
Tissue engineering. Part A, 21(7-8), 1432-1443 (2015-02-20)
Culture microenvironment plays a critical role in the propagation and differentiation of human embryonic stem cells (hESCs) and their differentiated progenies. Although high efficiency of hESC differentiation to keratinocytes (hESC-Kert) has been achieved, little is known regarding the effects of
Elisabetta Moratti et al.
PloS one, 10(3), e0119110-e0119110 (2015-03-17)
PTPRG is a widely expressed protein tyrosine phosphatase present in various isoforms. Peptides from its extracellular domain have been detected in plasma by proteomic techniques. We aim at characterizing the plasmatic PTPRG (sPTPRG) form and to identify its source. The
Ashwin Charles et al.
Journal of environmental management, 234, 404-411 (2019-01-15)
Palm oil mill effluent (POME) is a serious and expensive environmental problem in Malaysia. In this paper, CaFe2O4 is introduced as a novel photocatalyst for the degradation of POME under visible light irradiation. Two synthesis routes, auto-combustion and co-precipitation, and
Pin-Yi Lin et al.
Immunology, 144(4), 668-676 (2014-10-30)
T helper type 2 (Th2) cells, which produce interleukin-4 (IL-4), IL-5 and IL-13, control immunity to all forms of allergic inflammatory responses. Interleukin-21 (IL-21) reduces allergic symptoms in murine models and inhibits IL-4-induced IgE secretion by B cells. However, whether
Joshua C Eby et al.
Infection and immunity, 82(12), 5256-5269 (2014-10-08)
The adenylate cyclase toxin (ACT) of Bordetella pertussis intoxicates target cells by generating supraphysiologic levels of intracellular cyclic AMP (cAMP). Since ACT kills macrophages rapidly and potently, we asked whether ACT would also kill neutrophils. In fact, ACT prolongs the
Hayley Jensen et al.
Journal of environmental quality, 48(5), 1517-1523 (2019-10-08)
Iodine (I) is an essential trace element commonly deficient in agricultural systems. Whereas there is much information on I in food crops, there is a lacuna of knowledge on the environmental factors that affect pasture I concentrations. We aimed to
Hamed Valizadeh et al.
Mikrochimica acta, 186(7), 455-455 (2019-06-20)
A carbon paste electrode (CPE) modified with a metal-organic framework composite of type MIL-101(Fe) is described for determination of citric acid (CA). The electrochemical activity of the modified CPE was studied by cyclic voltammetry and differential pulse voltammetry. Scanning electron
Noriyo Nagata et al.
Journal of neuropathology and experimental neurology, 74(3), 250-260 (2015-02-11)
Neurotropic flavivirus infection of humans results in viremia subsequently; in some cases, it causes meningitis encephalomyelitis, although the pathways from viremia to central nervous system (CNS) invasion are uncertain. Here, we intravenously infected BALB/c mice with 3 neurotropic flaviviruses, then
Joanna Wojciechowska et al.
ChemSusChem, 12(3), 639-650 (2018-10-24)
Calcium-modified titania supported Ru catalysts were synthesized and evaluated for the hydrogenation of levulinic acid with formic acid as an internal hydrogen source and water as a green solvent. A new elegant photoassisted method was developed for the synthesis of
Monica Luminita Badea et al.
Molecules (Basel, Switzerland), 24(11) (2019-06-12)
This study aimed at developing an antimicrobial material based on hydroxyapatite (HAp) and peppermint essential oil (P-EO) in order to stimulate the antimicrobial activity of hydroxyapatite. The molecular spectral features and morphology of the P-EO, HAp and hydroxyapatite coated with
Keita Takahashi et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 201(4), 385-394 (2014-12-08)
Accessory lobes are protrusions located at the lateral sides of the spinal cord of chicks and it has been proposed that they play a role as a sensory organ for equilibrium during walking. We have reported that functional neurons exist
Min Liang et al.
Nitric oxide : biology and chemistry, 46, 114-122 (2014-12-20)
Hydrogen sulfide (H2S) has been reported to inhibit myocardial hypertrophy in a cell model of cardiomyocyte hypertrophy. Our previous study also shows an H2S-induced increase in glucose metabolism in insulin-targeting cells. The present study aims to examine the hypothesis that
Natasha Babar et al.
Investigative ophthalmology & visual science, 56(2), 1274-1282 (2015-01-31)
Previously, aliphatic β-nitroalcohols (BNAs) have been studied as a means to chemically induce tissue cross-linking (TXL) of cornea and sclera. There are a number of related and possibly more potent agents, known as formaldehyde releasers (FARs), that are in commercial
Ashwati Raghunath
BMJ case reports, 2013, doi:10-doi:10 (2013-01-04)
The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laboratory findings were unremarkable. He did not have any extra-pyramidal side
Selwyn S Jayakar et al.
Molecular and cellular neurosciences, 63, 1-12 (2014-08-30)
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic neuropeptide found at synapses throughout the central and autonomic nervous system. We previously found that PACAP engages a selective G-protein coupled receptor (PAC1R) on ciliary ganglion neurons to rapidly enhance quantal acetylcholine
Niloy Chandra Sarker et al.
Journal of environmental sciences (China), 82, 179-191 (2019-05-28)
Manure is an impending source of carbon (C), sulfur (S) and water (H2O). Consequently, microbial populations utilize these constituents to produce methane (CH4), carbon dioxide (CO2), greenhouse gases (GHGs), and hydrogen sulfide (H2S). Application of nanoparticles (NPs) to stored manure
Sang-Yong Lee et al.
Biochemical pharmacology, 93(2), 171-181 (2014-12-03)
Polyoxometalates (POMs) are inorganic cluster metal complexes that possess versatile biological activities, including antibacterial, anticancer, antidiabetic, and antiviral effects. Their mechanisms of action at the molecular level are largely unknown. However, it has been suggested that the inhibition of several
Jeong Hwan Oh et al.
Experimental brain research, 233(5), 1511-1518 (2015-02-24)
We previously found that the dopamine D2-type receptors (D2 and D3 receptors), coupled to protein kinase G (PKG), upregulate locomotor activity after repeated cocaine administration. In this study, D4 receptors, another type of D2 receptor also coupled to PKG, were
Sonam Vijay et al.
PloS one, 10(3), e0119666-e0119666 (2015-03-06)
Vector control is one of the major global strategies for control of malaria. However, the major obstacle for vector control is the development of multiple resistances to organochlorine, organophosphorus insecticides and pyrethroids that are currently being used in public health
Richard R Goulet et al.
Environmental toxicology and chemistry, 34(3), 562-574 (2014-12-06)
Treated effluent discharge from uranium (U) mines and mills elevates the concentrations of U, calcium (Ca), magnesium (Mg), and sulfate (SO4 (2-) ) above natural levels in receiving waters. Many investigations on the effect of hardness on U toxicity have
Carmen G León-Paravic et al.
The Journal of biological chemistry, 289(52), 36150-36157 (2014-11-12)
Hemichannels (HCs) are hexamers of connexins that can form gap-junction channels at points of cell contacts or "free HCs" at non-contacting regions. HCs are involved in paracrine and autocrine cell signaling, and under pathological conditions may induce and/or accelerate cell
Annemarie Tesch et al.
Materials science & engineering. C, Materials for biological applications, 81, 422-431 (2017-09-10)
Multimodal imaging has recently attracted much attention due to the advantageous combination of different imaging modalities, like photoluminescence (PL) and magnetic resonance imaging (MRI). In the present study, luminescent and magnetic hydroxyapatites (HAp) were prepared via doping with europium (Eu
Lenea Nørskov-Lauritsen et al.
FEBS letters, 589(5), 588-597 (2015-01-27)
Investigation of post-translational modifications of receptor proteins is important for our understanding of receptor pharmacology and disease physiology. However, our knowledge about post-translational modifications of class C G protein-coupled receptors and how these modifications regulate expression and function is very
Zhantao Han et al.
Water research, 70, 394-403 (2015-01-03)
This paper discusses the sorbent properties of magnetic activated carbons and biochars produced by wet impregnation with iron oxides. The sorbents had magnetic susceptibilities consistent with theoretical predictions for carbon-magnetite composites. The high BET surface areas of the activated carbons
Hokyung Song et al.
Materials science & engineering. C, Materials for biological applications, 48, 663-672 (2015-01-13)
Although regenerative medicine utilizing tissue scaffolds has made enormous strides in recent years, many constraints still hamper their effectiveness. A limitation of many scaffolds is that they form surface patches, which are not particularly effective for some types of "wounds"
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