224-168-1

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Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.

Jenny Chan et al.

The Journal of biological chemistry, 285(46), 36092-36099 (2010-09-17)

The three isoforms of the inositol 1,4,5-trisphosphate receptor (IP(3)R) exhibit distinct IP(3) sensitivities and cooperativities in calcium (Ca(2+)) channel function. The determinants underlying this isoform-specific channel gating mechanism have been localized to the N-terminal suppressor region of IP(3)R. We determined

Identification of human platelet alpha 2-adrenoceptors with a new antagonist [3H]-RX821002, a 2-methoxy derivative of idazoxan.

J Galitzky et al.

British journal of pharmacology, 100(4), 862-866 (1990-08-01)

1. The binding of a new alpha 2-adrenoceptor antagonist, [3H]-RX821002 (2-(2-methoxy-1,4-benzodioxan-2-yl)-2-imidazoline), was investigated in human platelet membranes and compared with [3H]-yohimbine binding parameters. 2. Analysis of kinetic data revealed association and dissociation time courses consistent with a simple biomolecular reaction.

Response surface methodology mediated optimization of Indanthrene Blue RS by a novel isolated bacterial strain Bacillus flexus TS8.

Swati Sambita Mohanty et al.

Water environment research : a research publication of the Water Environment Federation, 92(4), 569-578 (2019-09-27)

The enhanced decolorization and detoxification of Indanthrene Blue RS dye, under aerobic conditions, by a novel isolated anthraquinone-degrading bacterium, Bacillus flexus TS8, has been presented in this paper. The optimal decolorization conditions were determined by response surface methodology based on

MicroRNA hsa-miR-135b regulates mineralization in osteogenic differentiation of human unrestricted somatic stem cells.

Aneta M Schaap-Oziemlak et al.

Stem cells and development, 19(6), 877-885 (2009-10-03)

Unrestricted somatic stem cells (USSCs) have been recently identified in human umbilical cord blood and have been shown to differentiate into lineages representing all 3 germ layers. To characterize microRNAs that may regulate osteogenic differentiation of USSCs, we carried out

Z-DNA in the rat somatostatin gene.

T E Hayes et al.

The Journal of biological chemistry, 260(13), 8145-8156 (1985-07-05)

Two alternating purine-pyrimidine tracts flank the rat gene encoding the polypeptide hormone somatostatin. One lies 5' and one 3' to the gene; both consist of tandem repeats of the dinucleotide TG, with 25 repeats in the tract 5' and 15

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