224316

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Electrical switching of birefringence in zirconium phosphate colloids with various solvents.

Aurangzeb Rashid Masud et al.

Optics express, 26(1), 173-178 (2018-01-13)

Even though a graphene-oxide (GO) dispersion is attractive for electro-optical switching devices because of its high Kerr coefficient, it has several limitations such as chemical instability and optical loss due to absorption at visible wavelengths. Here we introduce the use

Melanocytic galectin-3 is associated with tyrosinase-related protein-1 and pigment biosynthesis.

Allison Chalupa et al.

The Journal of investigative dermatology, 135(1), 202-211 (2014-07-24)

Galectin-3 is a family member of the carbohydrate-binding proteins widely expressed by many cell types and exhibits multiple cellular functions. We demonstrate that melanocytes express galectin-3, which is predominantly localized to the cell body peripherally along the Golgi zone. Downregulation

Enzymatic Synthesis of Refined Olive Oil-Based Structured Lipid Containing Omega -3 and -6 Fatty Acids for Potential Application in Infant Formula.

Ruoyu Li et al.

Journal of food science, 80(11), H2578-H2584 (2015-09-27)

Structured lipids (SLs) containing palmitic, docosahexaenoic (DHA), and gamma-linolenic (GLA) acids were produced using refined olive oil, tripalmitin, and ethyl esters of DHA single cell oil and GLA ethyl esters. Immobilized Lipozyme TL IM lipase was used as the biocatalyst.

Development of alginate-reinforced chitosan nanoparticles utilizing W/O nanoemulsification/internal crosslinking technique for transdermal delivery of rabeprazole.

Tarek A Ahmed et al.

Life sciences, 110(1), 35-43 (2014-07-06)

First; to develop rabeprazole (RP)-alginate core coated chitosan nanoparticles (NP) utilizing water in oil (W/O) nanoemulsion technique. Second; formulation of transdermal patches loaded RP-NP that avoid drug peroral acid sensitivity and first pass effect. The influence of six factors on

A DNA-based molecular probe for optically reporting cellular traction forces.

Brandon L Blakely et al.

Nature methods, 11(12), 1229-1232 (2014-10-13)

We developed molecular tension probes (TPs) that report traction forces of adherent cells with high spatial resolution, can in principle be linked to virtually any surface, and obviate monitoring deformations of elastic substrates. TPs consist of DNA hairpins conjugated to

Subpathway-GMir: identifying miRNA-mediated metabolic subpathways by integrating condition-specific genes, microRNAs, and pathway topologies.

Li Feng et al.

Oncotarget, 6(36), 39151-39164 (2015-10-17)

MicroRNAs (miRNAs) regulate disease-relevant metabolic pathways. However, most current pathway identification methods fail to consider miRNAs in addition to genes when analyzing pathways. We developed a powerful method called Subpathway-GMir to construct miRNA-regulated metabolic pathways and to identify miRNA-mediated subpathways

Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream.

Andreas Lauterbach et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 614-624 (2014-12-03)

A novel adapalene-loaded solid lipid microparticle (SLMA) dispersion as a topical drug delivery system (TDDS) for follicular penetration has been introduced. The objective of the present study was to investigate the rheological properties, the follicular penetration with differential tape stripping

Effects of nutritional level of concentrate-based diets on meat quality and expression levels of genes related to meat quality in Hainan black goats.

Dingfa Wang et al.

Animal science journal = Nihon chikusan Gakkaiho, 86(2), 166-173 (2014-07-22)

The present study investigated the effects of the nutritional levels of diets on meat quality and related gene expression in Hainan black goat. Twenty-four goats were divided into six dietary treatments and were fed a concentrate-based diet with two levels

Controlled release studies of antimalarial 1, 3, 5-trisubstituted-2-pyrazolines from biocompatible chitosan-heparin Layer-by-Layer (LbL) self assembled thin films.

Uma M Bhalerao et al.

Colloids and surfaces. B, Biointerfaces, 125, 151-159 (2014-12-09)

Herein we report the in-vitro controlled release properties of 1, 3, 5-trisubstituted-2-pyrazolines through Layer-by-Layer (LbL) self assembled thin films fabricated from chitosan and heparin sodium salt as biocompatible polyelectrolytes. This study was carried out as a preliminary step towards the

Determination of nine hydroxylated polybrominated diphenyl ethers in water by precolumn derivatization-gas chromatography-mass spectrometry.

Boqu Yu et al.

Journal of chromatography. A, 1419, 19-25 (2015-10-12)

Hydroxylated polybrominated diphenyl ethers (OH-PBDEs), acting as emerging endocrine disruptors, have aroused more and more concern recently. Produced from natural source or metabolism of PBDEs, OH-PBDEs are more toxic than their parent compounds. However, few analytical methods are available for

Synthesis and characterization of a new cation exchanger-zirconium(IV)iodotungstate: separation and determination of metal ion contents of synthetic mixtures, pharmaceutical preparations and standard reference material.

Syed A Nabi et al.

Journal of hazardous materials, 172(1), 202-207 (2009-08-07)

Samples of zirconium(IV)iodotungstate have been synthesized under varying mixing order and ratios of aqueous solution of potassium iodate, sodium tungstate and zirconium oxychloride at pH 1. A tentative formula was proposed on the basis of chemical composition, FTIR and thermogravimetric

Determination of synthetic food colorants in fish products by an HPLC-DAD method.

G Karanikolopoulos et al.

Food chemistry, 177, 197-203 (2015-02-11)

Reliable methods for quantification of synthetic water-soluble colors in complex food matrices are currently not available. The present work describes the development and validation of an improved protocol for the analysis of synthetic food colorants in complex food matrices presenting

Single sea urchin phagocytes express messages of a single sequence from the diverse Sp185/333 gene family in response to bacterial challenge.

Audrey J Majeske et al.

Journal of immunology (Baltimore, Md. : 1950), 193(11), 5678-5688 (2014-10-31)

Immune systems in animals rely on fast and efficient responses to a wide variety of pathogens. The Sp185/333 gene family in the purple sea urchin, Strongylocentrotus purpuratus, consists of an estimated 50 (±10) members per genome that share a basic

Protein corona of nanoparticles: distinct proteins regulate the cellular uptake.

Sandra Ritz et al.

Biomacromolecules, 16(4), 1311-1321 (2015-03-21)

Understanding nanoparticle-protein interactions is a crucial issue in the development of targeted nanomaterial delivery. Besides unraveling the composition of the nanoparticle's protein coronas, distinct proteins thereof could control nanoparticle uptake into specific cell types. Here we differentially analyzed the protein

A new phenylpropanoid from the roots of Euphorbia nematocypha.

Hai-Yang Jia et al.

Natural product research, 29(7), 650-655 (2014-11-26)

A phytochemical investigation of the ethanolic extracts of the dried roots of Euphorbia nematocypha resulted in the isolation of a new phenylpropanoid, 16-O-caffeoyl-16-hydroxylhexadecanoic acid (1), together with 23 known compounds (2-24). Their structures were elucidated on the basis of spectroscopic

High surface area solids obtained by reaction of montmorillonite with zirconyl chloride.

Yamanaka S and Brindley GW.

Clays and Clay Minerals, 27(2), 119-119 (1979)

Development of sample clean up methods for the analysis of Mycobacterium tuberculosis methyl mycocerosate biomarkers in sputum extracts by gas chromatography-mass spectrometry.

Simona C Nicoara et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 135-142 (2015-03-03)

A proof of principle gas chromatography-mass spectrometry method is presented, in combination with clean up assays, aiming to improve the analysis of methyl mycocerosate tuberculosis biomarkers from sputum. Methyl mycocerosates are generated from the transesterification of phthiocerol dimycocerosates (PDIMs), extracted

Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10.

Akira Onishi et al.

Laboratory investigation; a journal of technical methods and pathology, 95(12), 1353-1362 (2015-09-15)

Peritoneal fibrosis (PF), a serious pathophysiology of peritoneal dialysis (PD), is implicated in various types of chronic inflammation. In the present study, we examined the benefits of interleukin (IL)-10, which exerts anti-inflammatory effects, in an experimental rat model of methylglyoxal

Prevention of pulmonary hypoplasia and pulmonary vascular remodeling by antenatal simvastatin treatment in nitrofen-induced congenital diaphragmatic hernia.

Martine Makanga et al.

American journal of physiology. Lung cellular and molecular physiology, 308(7), L672-L682 (2015-01-27)

Congenital diaphragmatic hernia (CDH) has a high mortality rate mainly due to lung hypoplasia and persistent pulmonary hypertension of the newborn (PPHN). Simvastatin has been shown to prevent the development of pulmonary hypertension (PH) in experimental models of PH. We

Simultaneous determination of triamcinolone acetonide palmitate and triamcinolone acetonide in beagle dog plasma by UPLC-MS/MS and its application to a long-term pharmacokinetic study of triamcinolone acetonide palmitate lipid emulsion injection.

Hui Liu et al.

Journal of pharmaceutical and biomedical analysis, 104, 105-111 (2014-12-17)

In order to investigate the pharmacokinetics of triamcinolone acetonide palmitate (TAP) which is a lipid-soluble prodrug of triamcinolone acetonide (TA), a rapid, simple, sensitive and reproducible UPLC-MS/MS method has been developed and validated for the simultaneous determination of TAP and

Antioxidant activity of hyaluronic acid investigated by means of chemiluminescence of equine neutrophil bursts and electron paramagnetic resonance spectroscopy.

P C Braga et al.

Journal of veterinary pharmacology and therapeutics, 38(1), 48-54 (2014-07-30)

Activated neutrophils (PMNs), the ROS/RNS released by PMNs and the derived inflammatory processes are involved in the pathogenesis and progression of human inflammatory airway diseases. Similar diseases are also present in horses which suffer from recurrent airway obstruction (RAO), exercise-induced

The effect of lacosamide on bone tissue in orchidectomised male albino Wistar rats.

Julius Simko et al.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 159(3), 394-399 (2014-02-11)

While most antiepileptic drugs (AEDs) have been associated with various adverse effects on bone health, for the recently introduced lacosamide (LCM) no corresponding data have been published. The present study evaluates the effect of LCM on bone mineral density, bone

Benzaldehyde as an insecticidal, antimicrobial, and antioxidant compound produced by Photorhabdus temperata M1021.

Ihsan Ullah et al.

Journal of microbiology (Seoul, Korea), 53(2), 127-133 (2015-01-30)

The Photorhabdus temperata M1021 secretes toxic compounds that kill their insect hosts by arresting immune responses. Present study was aimed to purify the insecticidal and antimicrobial compound(s) from the culture extract of P. temperata M1021 through bioassay guided fractionation. An

Morphometric Study of Diabetes Related Alterations in Human Parotid Gland and Comparison with Submandibular Gland.

Maria Alberta Lilliu et al.

Anatomical record (Hoboken, N.J. : 2007), 298(11), 1911-1918 (2015-08-13)

Type 2 diabetes mellitus represents one of the principal diseases that afflict the world population and is often associated with malfunction of salivary glands and consequent oral diseases. We recently described significant ultrastructural alterations in the human submandibular gland in

Protective Effect of Lavandula stoechas and Rosmarinus officinalis essential oils against reproductive damage and oxidative stress in alloxan-induced diabetic rats.

Hichem Sebai et al.

Journal of medicinal food, 18(2), 241-249 (2014-08-12)

The authors aimed in the present study to assess the protective effect of Rosmarinus officinalis essential oils (ROEO) and Lavandula stoechas essential oils (LSEO) against reproductive damage and oxidative stress in alloxan-induced diabetic male rats. Essential oil samples were obtained

Impact of the structure of biocompatible aliphatic polycarbonates on siRNA transfection ability.

Antoine Frère et al.

Biomacromolecules, 16(3), 769-779 (2015-01-21)

RNAi therapeutics are promising therapeutic tools that have sparked the interest of many researchers. In an effort to provide a safe alternative to PEI, we have designed a series of new guanidinium- and morpholino-functionalized biocompatible and biodegradable polycarbonate vectors. The

Growth Performance of Early Finishing Gilts as Affected by Different Net Energy Concentrations in Diets.

Gang Il Lee et al.

Asian-Australasian journal of animal sciences, 28(11), 1614-1623 (2015-09-04)

The objectives of the current experiment were to study the response of the growth performance of early finishing gilts to different net energy (NE) concentrations in diets, and to compare the NE values of diets between calculated NE values and

EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer.

Lucas J Brand et al.

Oncotarget, 6(6), 3811-3824 (2015-02-12)

The androgen receptor (AR) is a driver of prostate cancer (PCa) cell growth and disease progression. Therapies for advanced PCa exploit AR dependence by blocking the production or action of androgens, but these interventions inevitably fail via multiple mechanisms including

One-step separation of nine structural analogues from Poria cocos (Schw.) Wolf. via tandem high-speed counter-current chromatography.

Hualiang Zeng et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1004, 10-16 (2015-10-06)

A novel one-step separation strategy-tandem high-speed counter-current chromatography (HSCCC) was developed with a six-port valve serving as the switch interface. Nine structural analogues including three isomers were successfully isolated from Poria cocos (Schw.) Wolf. by one step. Compared with conventional

Development of a multi-toxin method for investigating the carryover of zearalenone, deoxynivalenol and their metabolites into milk of dairy cows.

Janine Winkler et al.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(3), 371-380 (2015-04-08)

A dose-response study was carried out to examine the carryover of zearalenone (ZEN), deoxynivalenol (DON) and their metabolites into bovine milk. Therefore, a feeding trial with 30 dairy cows fed with three different levels of Fusarium (FUS) toxin-contaminated maize was

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