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关键词:'229857'
显示 31-60 共 83 条结果 关于 "229857" 范围 论文
P Díaz et al.
Research in veterinary science, 99, 120-128 (2015-02-01)
Mesenchymal stem cells (MSC) are multipotent progenitor cells defined by their ability to self-renew and give rise to differentiated progeny. Since MSC from adult tissues represent a promising source of cells for a wide range of cellular therapies, there is
Bo Wei et al.
Journal of biomaterials applications, 30(2), 160-170 (2015-03-15)
The goal of this study was to investigate the chondrogenic potential of three-dimensional polycaprolactone-hydroxyapatite (PCL-HA) scaffolds loaded with bone marrow cells in vitro and the effect of PCL-HA scaffolds on osteochondral repair in vivo. Here, bone marrow was added to
Alexander D Cigan et al.
Tissue engineering. Part A, 19(17-18), 1941-1948 (2013-04-03)
The primary goal of this study was to characterize the response of chondrocyte-seeded agarose constructs to varying concentrations of several key nutrients in a chondrogenic medium, within the overall context of optimizing the key nutrients and the placement of nutrient
Mehmet Isyar et al.
Journal of orthopaedic surgery and research, 10, 118-118 (2015-08-01)
The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Primary cell cultures obtained from gonarthrosis patients were divided into four groups, two of which were designated as
Jennifer K Lee et al.
Arthritis research & therapy, 17, 28-28 (2015-04-18)
The aim of this study was to investigate the effects of thyroid hormones tri-iodothyronine (T3), thyroxine (T4), and parathyroid hormone (PTH) from the parathyroid glands, known to regulate the developing limb and growth plate, on articular cartilage tissue regeneration using
Antonio G Soto et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(27), E3600-E3608 (2015-06-24)
Protease-activated receptor-1 (PAR1) is a G-protein-coupled receptor (GPCR) for the coagulant protease thrombin. Similar to other GPCRs, PAR1 is promiscuous and couples to multiple heterotrimeric G-protein subtypes in the same cell and promotes diverse cellular responses. The molecular mechanism by
Jianchao Gui et al.
Current stem cell research & therapy, 10(4), 353-363 (2015-05-20)
The successful surgical restoration of damaged meniscus has been a challenge, largely owing to a lack of characterization of meniscus cells and their precursors. Numerous strategies to repair or replace meniscus have achieved only limited success. Several recent studies have
Priscilla Soulié et al.
American journal of physiology. Cell physiology, 307(8), C745-C759 (2014-08-29)
Generation of branched tubes from an epithelial bud is a fundamental process in development. We hypothesized that induction of hyaluronan synthase (Has) and production of hyaluronan (HA) drives tubulogenesis in response to morphogenetic cytokines. Treatment of J3B1A mammary cells with
V van Drongelen et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 44(12), 1515-1524 (2014-10-30)
Atopic dermatitis is an inflammatory skin disease that is characterized by a reduced skin barrier function, reduced filaggrin (FLG) expression as well as increased colonization by Staphylococcus aureus. This study focused on the possible involvement of FLG in epidermal colonization
Nina Ilić et al.
Vojnosanitetski pregled, 71(7), 651-659 (2014-08-12)
Mesenchymal stromal cells (MSCs) have been utilised in many clinical trials as an experimental treatment in numerous clinical settings. Bone marrow remains the traditional source tissue for MSCs but is relatively hard to access in large volumes. Alternatively, MSCs may
Henriette Jülke et al.
Cell transplantation, 24(6), 1111-1125 (2013-12-18)
The purpose of this study was to evaluate the use of three different superparamagnetic iron oxide (SPIO) particles for labeling of ovine and equine bone marrow (BM)-derived multipotent stromal cells (MSCs) in vitro. MSCs were obtained from five adult sheep
Can-Peng Li et al.
Food chemistry, 148, 209-217 (2013-11-23)
Ovalbumin (OVA) was selenized by dry-heating in the presence of selenite, and the structural characteristics and improved antioxidant activity of selenized OVA (Se-OVA) were investigated. Although the change of the secondary structure in the OVA molecule by selenization was small
Ropp RC et al.
Encyclopedia of the Alkaline Earth Compounds null
Ji-Kan Ryu et al.
The journal of sexual medicine, 11(2), 411-423 (2013-11-21)
Recently, much attention has focused on stem cell therapy; bone marrow-derived stem cells (BMSCs) are one of the most studied mesenchymal stem cells used in the field of erectile dysfunction (ED). However, a major limitation for the clinical application of
Hisayuki Yao et al.
Stem cells (Dayton, Ohio), 32(8), 2245-2255 (2014-03-22)
Parathyroid hormone (PTH) stimulates hematopoiesis in mouse models. The involvement of osteoblasts in this process has been well investigated; however, the effects of PTH on human hematopoiesis and bone marrow mesenchymal stromal cells (BM-MSCs) are unclear. Here, we show that
Omar M Young et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 73(1), 22-35 (2014-10-28)
Microbial-driven responses in placenta are linked with adverse pregnancy outcomes. The role of Toll-like receptor (TLR) function in Hofbauer cells (HBCs) and fetal macrophages of the placental villous core remains understudied. Flow cytometry and immunohistochemistry (IHC) were used to establish
Paula B Caffrey et al.
Anticancer research, 33(10), 4249-4254 (2013-10-15)
We have been exploring a prevention approach to the problem of drug resistance which develops during ovarian cancer chemotherapy. We have previously described an in vivo model of the development of resistance to the chemotherapy drug cisplatin in xenografts, and
S Miller et al.
Biochimica et biophysica acta, 1588(1), 85-93 (2002-10-16)
Selenium (Se) can protect endothelial cells (EC) from oxidative damage by altering the expression of selenoproteins with antioxidant function such as cytoplasmic glutathione peroxidase (cyGPX), phospholipid hydroperoxide glutathione peroxidase (PHGPX) and thioredoxin reductase (TR). If the role of Se on
Sheng-Yi Zhang et al.
The journal of physical chemistry. B, 110(18), 9041-9047 (2006-05-05)
This article describes a rapid, solution-phase approach to the large-scale synthesis of faceted single-crystalline Se nanotubes, in the presence of cetyltrimethylammonium bromide. The products were characterized by scanning electron microscopy, high-resolution transmission electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, laser
D Hatsushika et al.
Osteoarthritis and cartilage, 22(7), 941-950 (2014-05-06)
A new strategy is required in order to regenerate a meniscus for extensive defects. Synovial mesenchymal stem cells (MSCs) are an attractive cell source for meniscus regeneration due to their high proliferation and chondrogenic potential. We examined the effect of
Selenium metabolite levels in human urine after dosing selenium in different chemical forms.
R Hasunuma et al.
Bulletin of environmental contamination and toxicology, 51(5), 756-763 (1993-11-01)
Lu Fan et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 68(8), 1141-1148 (2014-12-03)
Sarco/endoplasmic reticulum calcium ATPase (SERCA) enzymes play important roles in several signal transduction pathways that control proliferation, differentiation and apoptosis. Here, we reported that SERCA2 expression was positively correlated with tumor node metastasis (TNM) stages (n=75, P=0.0251) and grades (n=63
C H Zheng et al.
European cells & materials, 29, 224-236 (2015-04-22)
The 1,9-dimethylmethylene blue (DMMB) assay is widely used to quantify sulfated glycosaminoglycan (sGAG) contents of engineered tissues, culture media, tissue samples and bodily fluids, but the assay is subject to interference from polyanions such as hyaluronic acid (HA), DNA and
Y Kayanoki et al.
Journal of biochemistry, 119(4), 817-822 (1996-04-01)
Selenium-dependent glutathione peroxidase (GPx) plays a protective role in oxidative stress-induced apoptosis. In this study, we demonstrated that MDBK cells, a bovine renal epithelial cell line, exhibited internucleosomal DNA fragmentation characteristic of apoptotic cell death under selenium-deficient conditions with lower
M Rizki et al.
Environmental and molecular mutagenesis, 37(1), 70-75 (2001-02-15)
The genotoxic activity of three selenium compounds (sodium selenite, sodium selenate, and selenious acid) and the antigenotoxic effects of sodium selenite in combination with the chromium compound potassium dichromate were studied using the wing spot test of Drosophila melanogaster. This
Diana Seidel et al.
Cancer immunology, immunotherapy : CII, 64(5), 621-634 (2015-02-26)
The disialoganglioside GD2 is a well-established target antigen for passive immunotherapy in neuroblastoma (NB). Despite the recent success of passive immunotherapy with the anti-GD2 antibody ch14.18 and cytokines, treatment of high-risk NB remains challenging. We expanded the approach of GD2-specific
Z J Wang et al.
Biological trace element research, 33, 135-143 (1992-04-01)
A common intermediate, i.e., selenite, was found in the serum of the rat; the maximum levels occurred 3 h after administration independent of chemical forms. This indicates that both the reduction of selenate to selenite, and oxidation of seleno-dl-methionine to
R K Bentsen et al.
Science & justice : journal of the Forensic Science Society, 36(1), 3-8 (1996-01-01)
A considerable range of techniques is available to visualise latent fingerprints on smooth surfaces. Published methods and those developed or modified in the authors' laboratory have been evaluated for spent cartridge cases. The most suitable were found to be vacuum
Guojian Yin et al.
International journal of clinical and experimental pathology, 8(5), 4457-4468 (2015-07-21)
Mesenchymal stem cells (MSCs) have shown an obvious protective effect on systemic inflammation. The purpose of this study is to assess the effect and possible mechanism of bone marrow MSCs (bmMSCs) on acute pancreatitis (AP). BmMSCs of SD rats were
Indira Prasadam et al.
Rheumatology (Oxford, England), 53(12), 2280-2287 (2014-07-06)
The aim of this study was to test the possible involvement, relevance and significance of dentin matrix protein 1 (DMP1) in chondrocyte redifferentiation and OA. To examine the function of DMP1 in vitro, bone marrow stromal cells (BMSCs) and articular
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