Methods for the detection and estimation of diphosgene and triphosgene are described. These compounds are widely used phosgene precursors which produce an intensely colored purple pentamethine oxonol dye when reacted with 1,3-dimethylbarbituric acid (DBA) and pyridine (or a pyridine derivative).
Topics in Inorganic and General Chemistry, 24, 535-541 (1996)
Synthesis of some aromatic diisocyanides with trichloromethyl chloroformate.
Efraty A, et al.
The Journal of Organic Chemistry, 45(20), 4059-4061 (1980)
An improved rapid method for the synthesis of N-carboxy. alpha.-amino acid anhydrides using trichloromethyl chloroformate.
Katakai R and Iizuka Y
The Journal of Organic Chemistry, 50(5), 715-716 (1985)
Single-pot reductive conversion of amino acids to their respective 2-oxazolidinones employing trichloromethyl chloroformate as the acylating agent: A multigram synthesis.
Pridgen L N, et al.
The Journal of Organic Chemistry, 54(13), 3231-3233 (1989)
R. Katakai et al.
The Journal of Organic Chemistry, 50, 715-715 (1985)
Groups of young adult Wistar rats were acutely exposed to trichloromethyl chloroformate (diphosgene) and bis(trichloromethyl) carbonate (triphosgene) vapor atmospheres using a directed-flow nose-only mode of exposure. The exposure duration used was 240 min. The median lethal concentration (LC50) of diphosgene
H. Ogura et al.
Bulletin of the Chemical Society of Japan, 56, 2485-2485 (1983)