242-024-6

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A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.

So-Young Yi et al.

Clinical pharmacology and therapeutics, 76(5), 418-427 (2004-11-13)

There have been considerable disagreements regarding the influence of MDR1 (ABCB1) polymorphisms on the disposition of P-glycoprotein (P-gp) substrates. We speculated that the unknown function of the A allele of exon 21 G2677T/A (Ala893Ser/Thr) provides one of the reasons for

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