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Krzysztof Zapałowicz et al.
Neurologia i neurochirurgia polska, 47(6), 590-594 (2014-01-01)
The authors describe the use of bone cement containing calcium phosphate for vertebroplasty of the cavity in the base of odontoid process. A 23-year-old female patient was operated on by incision in lateral cervical area (anterior open access). After a
Huan Zhou et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 4288-4294 (2013-08-06)
There are two interesting features of this paper. First, we report herein a novel microwave assisted technique to prepare phosphate based orthopedic cements, which do not generate any exothermicity during setting. The exothermic reactions during the setting of phosphate cements
Francisco Miguel Cardoso et al.
Journal of virology, 88(15), 8278-8296 (2014-05-16)
Influenza virus neuraminidase (NA) is an interesting target of small-molecule antiviral drugs. We isolated a set of H5N1 NA-specific single-domain antibodies (N1-VHHm) and evaluated their in vitro and in vivo antiviral potential. Two of them inhibited the NA activity and
Senthilguru Kulanthaivel et al.
Materials science & engineering. C, Materials for biological applications, 58, 648-658 (2015-10-20)
The present study delineates the synthesis and characterization of cobalt doped proangiogenic-osteogenic hydroxyapatite. Hydroxyapatite samples, doped with varying concentrations of bivalent cobalt (Co(2+)) were prepared by the ammoniacal precipitation method and the extent of doping was measured by ICP-OES. The
Darcy E Wagner et al.
Acta biomaterialia, 9(9), 8422-8432 (2013-06-15)
Biocompatible nanoparticles possessing fluorescent properties offer attractive possibilities for multifunctional bioimaging and/or drug and gene delivery applications. Many of the limitations with current imaging systems center on the properties of the optical probes in relation to equipment technical capabilities. Here
Hamid Esfahani et al.
Journal of colloid and interface science, 443, 143-152 (2014-12-30)
Surface modification of electrospun polymeric membrane surfaces is a critical step towards the separation process including protein adsorption. In this study, the electrospun Nylon fibers was incorporated with positively charged zinc doped hydroxyapatite (HAp) nanoparticles to study the adsorption of
Ariba Farooq et al.
Materials science & engineering. C, Materials for biological applications, 56, 104-113 (2015-08-08)
Development of biodegradable composites having the ability to suppress or eliminate the pathogenic micro-biota or modulate the inflammatory response has attracted great interest in order to limit/repair periodontal tissue destruction. The present report includes the development of non-steroidal anti-inflammatory drug
Sien Lin et al.
Calcified tissue international, 96(6), 541-551 (2015-03-31)
Previous studies reported that statins showed positive effects on bone in both human and animal models. This study aimed to investigate the effects of atorvastatin on the prevention of osteoporosis and dyslipidemia in ovariectomized rats fed with high-fat emulsion. The
Thomas Lyon et al.
The Journal of bone and joint surgery. American volume, 95(23), 2088-2096 (2013-12-07)
Recombinant human bone morphogenetic protein-2 (rhBMP-2) applied on an absorbable collagen sponge improves open tibial fracture-healing as an adjunct to unreamed intramedullary nail fixation. We evaluated rhBMP-2 and a new, injectable calcium phosphate matrix (CPM) formulation in acute closed tibial
Bernhard Gasselhuber et al.
Biochemistry, 54(35), 5425-5438 (2015-08-21)
Recently, it was demonstrated that bifunctional catalase-peroxidases (KatGs) are found not only in archaea and bacteria but also in lower eukaryotes. Structural studies and preliminary biochemical data of the secreted KatG from the rice pathogen Magnaporthe grisea (MagKatG2) suggested both
Naomi M de Almeida et al.
Journal of bacteriology, 197(14), 2432-2441 (2015-05-13)
Anaerobic ammonium-oxidizing (anammox) bacteria oxidize ammonium with nitrite as the terminal electron acceptor to form dinitrogen gas in the absence of oxygen. Anammox bacteria have a compartmentalized cell plan with a central membrane-bound "prokaryotic organelle" called the anammoxosome. The anammoxosome
R Selvaraju et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 114, 650-657 (2013-07-03)
In the present study the human urinary stones were observed in their different chemical compositions of calcium oxalate monohydrate, calcium oxalate dihydrate, calcium phosphate, struvite (magnesium ammonium phosphate), uric acid, cystine, oxammite (ammonium oxalate monohydrate), natroxalate (sodium oxalate), glushinkite (magnesium
Tie Liu et al.
Bone, 56(1), 110-118 (2013-06-05)
As an alternative to an autologous bone graft, deproteinized bovine bone (DBB) is widely used in the clinical dentistry. Although DBB provides an osteoconductive scaffold, it is not capable of enhancing bone regeneration because it is not osteoinductive. In order
Haydar Çelik et al.
Molecular cancer therapeutics, 14(11), 2497-2507 (2015-09-12)
Ezrin is a member of the ERM (ezrin, radixin, moesin) family of proteins and functions as a linker between the plasma membrane and the actin cytoskeleton. Ezrin is a key driver of tumor progression and metastatic spread of osteosarcoma. We
An injectable BMP cocktail for fracture-healing--a study that others have only imagined: commentary on an article by Thomas Lyon, MD, et al.: "Efficacy and safety of recombinant human bone morphogenetic protein-2/calcium phosphate matrix for closed tibial diaphyseal fracture. a double-blind, randomized, controlled phase-II/III trial".
Cory Collinge
The Journal of bone and joint surgery. American volume, 95(23), e1891-e1892 (2013-12-07)
Daniel M Moreira et al.
The Journal of urology, 190(6), 2106-2111 (2013-06-15)
We determined the accuracy of 24-hour urinalysis in predicting stone type and identify the associations between 24-hour urine elements with stone type. We performed a retrospective review of 503 stone formers with stone composition analysis and 24-hour urinalysis available. Analysis
Chen Li et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 114, 575-578 (2013-07-03)
Eu(2+)-Yb(3+) co-doped transparent glass-ceramic containing nano-Ca5(PO4)3F (FAP) was prepared in reducing atmosphere. XRD and TEM analysis indicated that nano-FAP about 40 nm precipitated homogeneously in glass matrix after heat treatment. Confirmed by spectroscopy measurements, the crystal-like absorption and emission of
Radosław Olkowski et al.
Journal of materials science. Materials in medicine, 26(12), 270-270 (2015-10-30)
Calcium phosphate cements (CPC) are valuable bone fillers. Recently they have been also considered as the basis for drug-, growth factors- or cells-delivery systems. Broad possibilities to manipulate CPC composition provide a unique opportunity to obtain materials with a wide
E Buraka et al.
Chemico-biological interactions, 220, 200-207 (2014-07-13)
The ability to intercalate between DNA strands determines the cytotoxic activity of numerous anticancer drugs. Strikingly, intercalating activity was also reported for some compounds considered to be antimutagenic. The aim of this study was to determine the mode of interaction
Lin Lu et al.
Journal of applied biomaterials & functional materials, 12(3), 145-154 (2014-01-16)
Polycaprolactone (PCL) and polycaprolactone-hydroxyapatite (PCL-HA) scaffolds with 600-µm pore size were fabricated by drop-on-demand printing (DDP) structured porogen method followed with injection molding. Specimens with special dimensions of 4.2×4.2×5.4 mm3 and 6.6×6.6×13.8 mm3 were designed and fabricated for compression and
Marc A Fernandez-Yague et al.
Advanced drug delivery reviews, 84, 1-29 (2014-09-23)
The development of responsive biomaterials capable of demonstrating modulated function in response to dynamic physiological and mechanical changes in vivo remains an important challenge in bone tissue engineering. To achieve long-term repair and good clinical outcomes, biologically responsive approaches that
Kushagra Saran et al.
Advanced healthcare materials, 4(3), 432-445 (2014-10-10)
During minimally invasive orthopedic surgeries, surgical intervention is required at two stages; to attain hemostasis and subsequently to implant the bone graft or its substitute. There is an apparent need for a material which can simultaneously control bone bleeding and
Georgios N Belibasakis et al.
Virulence, 6(7), 704-709 (2015-08-26)
Periodontitis is an infectious inflammatory disease that destroys the tooth-supporting tissues. It is caused by the formation of subgingival biofilms on the surface of the tooth. Characteristic bacteria associated with subgingival biofilms are the Gram-negative anaerobes Porphyromonas gingivalis, Tannerella forsythia
Sayed Modinur Rahaman et al.
Indian journal of biochemistry & biophysics, 52(2), 119-124 (2015-06-30)
The role of angiotensin II in regulating Na+/K(+)-ATPase activity has been investigated in bovine pulmonary artery smooth muscle cells (BPASMCs). Our study reveals that angiotensin II inhibits the Na+/K+ATPase activity via glutathionylation of the pump with the involvement of an
Gregor Buehrer et al.
Tissue engineering. Part A, 21(1-2), 96-105 (2014-08-20)
In this study the induction of bone formation in an axially vascularized bone matrix using mesenchymal stem cells (MSCs) and application of bone morphogenetic protein 2 (BMP2) was analyzed in the arteriovenous loop (AVL) model. An AVL was created in
Ui-Won Jung et al.
Journal of periodontal & implant science, 43(2), 64-71 (2013-05-17)
The objective of this study was to elucidate the role of collagen membranes (CMs) when used in conjunction with bovine hydroxyapatite particles incorporated with collagen matrix (BHC) for lateral onlay grafts in dogs. The first, second, and third premolars in
Alberto Nilo et al.
ACS chemical biology, 10(7), 1737-1746 (2015-04-24)
Gram-positive Streptococcus agalactiae or group B Streptococcus (GBS) is a leading cause of invasive infections in pregnant women, newborns, and elderly people. Vaccination of pregnant women represents the best strategy for prevention of neonatal disease, and GBS polysaccharide-based conjugate vaccines
Taichi Inui et al.
Applied and environmental microbiology, 81(16), 5471-5476 (2015-06-07)
Carbohydrate availability shifts when bacteria attach to a surface and form biofilm. When salivary planktonic bacteria form an oral biofilm, a variety of polysaccharides and glycoproteins are the primary carbon sources; however, simple sugar availabilities are limited due to low
Petra Korlević et al.
BioTechniques, 59(2), 87-93 (2014-01-01)
Although great progress has been made in improving methods for generating DNA sequences from ancient biological samples, many, if not most, samples are still not amenable for analyses due to overwhelming contamination with microbial or modern human DNA. Here we
Minsung Park et al.
Colloids and surfaces. B, Biointerfaces, 130, 222-228 (2015-04-26)
Nanofibrous 2,2,6,6-tetramethylpiperidine-1-oxyl(TEMPO)-oxidized bacterial cellulose (TOBC) was used as a dispersant of hydroxyapatite (HA) nanoparticles in aqueous solution. The surfaces of TOBC nanofibers were negatively charged after the reaction with the TEMPO/NaBr/NaClO system at pH 10 and room temperature. HA nanoparticles
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