developed in rabbit using a synthetic peptide derived
from the region of MEK 1 that contains serine 298 as
immunogen. The serum is affinity purified using
sequential epitope-specific affinity chromatography
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dual-phosphorylation,
which occurs on serines 218 and 222, in the activation
loop of the MEKs. Serine 298 of MEK 1 is
phosphorylated by PAK1, which promotes MEK 1
binding to c-Raf and its subsequent
phosphorylation, which occurs on serines 218 and 222,
in the activation loop of the MEKs. Serine 298 of MEK
2 is phosphorylated by PAK1, which promotes MEK 2
M NP_001004720.1 y n/d y
520 O-GlcNAc Transferase O6264 8473 OGT P NP_858058.1 ,NP_858059.1 y y y
298 Gemin 2 G6669 8487 SIP1 M NP_001009182.1 ,NP_001009183.1 , NP_003607.1 y y y
320 HAT1 ( Histone acetyltransferase
M NP_001004720.1 y n/d y
520 O-GlcNAc Transferase O6264 8473 OGT P NP_858058.1 ,NP_858059.1 y y y
298 Gemin 2 G6669 8487 SIP1 M NP_001009182.1 ,NP_001009183.1 , NP_003607.1 y y y
320 HAT1 ( Histone acetyltransferase
M NP_001004720.1 y n/d y
520 O-GlcNAc Transferase O6264 8473 OGT P NP_858058.1 ,NP_858059.1 y y y
298 Gemin 2 G6669 8487 SIP1 M NP_001009182.1 ,NP_001009183.1 , NP_003607.1 y y y
320 HAT1 ( Histone acetyltransferase
G6666 M y n/d n/d
295 GAPDH G8795 M y y y
296 GATA-1 G0290 P y n/d n/d
297 Gelsolin G4896 M y n/d n/d
298 Gemin 2 G6669 M y y y
299 Gemin 3 G6544 M y n/d n/d
300 GFAP (Glial Fibrillary
GATA-1 G0290 2623 GATA1 NP_002040.1 P y n/d n/d
297 Gelsolin G4896 2934 GSN NP_937895.1 M y n/d n/d
298 Gemin 2 G6669 8487, 66603, 84404 SIP1,Sip1 NP_003607.1,NP_079932.2,NP_445841.1 M y y y
299 Gemin 3
GATA-1 G0290 2623 GATA1 NP_002040.1 P y n/d n/d
297 Gelsolin G4896 2934 GSN NP_937895.1 M y n/d n/d
298 Gemin 2 G6669 8487, 66603, 84404 SIP1,Sip1 NP_003607.1,NP_079932.2,NP_445841.1 M y y y
299 Gemin 3
Ascites M IgM 200 µL 05-593
Rb Ca
Anti-α-Dystroglycan VIA4-1 H M R Gp WB IH Sup M IgG1 200 µL 05-298
Rb Ca
Cranin [Dystroglycan] 6C1 H M R Sh ELISA IC IH Asc M