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Alfonso Pérez-Garrido et al.
Bioorganic & medicinal chemistry, 17(2), 896-904 (2008-12-06)
This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the molecular structure of the compounds under investigation
Joseph P Mazzoncini et al.
The Journal of emergency medicine, 38(4), 456-459 (2008-07-01)
Human metapneumovirus (hMPV) is an important emerging respiratory pathogen, previously unreported in the Emergency Medicine literature. It is primarily associated with the clinical syndromes of bronchiolitis and pneumonia. hMPV may predispose to bacterial pneumonia; coinfection with respiratory syncytial virus may
B Ward et al.
Epidemiology and infection, 129(2), 287-293 (2002-10-31)
We investigated an outbreak of 54 cases of Salmonella Typhimurium phage type 9 (STM9) with a specific antibiotic resistance pattern. We used sequential analytic studies: two retrospective cohort studies, a case-control study, and a modified case-control study. An outbreak of
Deepanker Tewari et al.
Foodborne pathogens and disease, 9(10), 928-933 (2012-09-08)
The aim of this study was to identify Salmonella serotypes infecting cattle in Pennsylvania, to compare infection rates for the predominant serotype, Salmonella enterica serotype Cerro, with the infection rates for the same serotype in humans, and to study the
Ilaria Massarelli et al.
European journal of medicinal chemistry, 44(9), 3658-3664 (2009-03-11)
A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above unwanted property for New Chemical Entities. The dataset was rationally split into
Charles E Ahlfors
The Journal of pediatrics, 144(3), 386-388 (2004-03-06)
Ibuprofen is used for closing the ductus arteriosus in premature newborn infants. Ibuprofen interferes with bilirubin-albumin binding and increases the unbound bilirubin in pooled newborn plasma to levels similar to those produced by sulfisoxazole, a drug that causes kernicterus in
Application of ion-exchange cartridge clean-up in food analysis: V. Simultaneous determination of sulphonamide antibacterials in animal liver and kidney using high-performance liquid chromatography with ultraviolet and mass spectrometric detection
Ito Y, et al.
Journal of Chromatography A, 898(1), 95-102 (2000)
Abdulilah Dawoud Bani-Yaseen
Journal of fluorescence, 21(3), 1061-1067 (2010-12-25)
The Fluorescence spectroscopic and solvatochromic behavior of Sulfisoxazole, a sulfa drug with antimicrobial activities, in various pure solvents of different polarity and hydrogen bonding capability is reported. The fluorescence emission spectrum of sulfisoxazole was found to be solvent polarity dependent
Hui-zhen Wu et al.
Analytical and bioanalytical chemistry, 407(13), 3545-3554 (2015-03-04)
An in-line matrix cleanup method was used for the simultaneous extraction of 15 sulfonamides and two metabolites from manure samples. The ultrasound/microwave-assisted extraction (UMAE) combined with solid-liquid-solid dispersive extraction (SLSDE) procedure provides a simple sample preparation approach for the processing
Katrijn Cobbaut et al.
Foodborne pathogens and disease, 8(6), 719-724 (2011-03-09)
During a Escherichia coli O157 prevalence study on cattle farms, 324 E. coli O157 isolates were collected from 68 out of 180 cattle farms. All isolates harbored the eaeA gene and the enterohemolysin (ehxA) gene. The majority of the strains
Reply to 'Sulfisoxazole does not inhibit the secretion of small extracellular vesicles'.
Chan-Hyeong Lee et al.
Nature communications, 12(1), 976-976 (2021-02-14)
Magda Targa Martins et al.
Talanta, 129, 374-383 (2014-08-17)
In routine laboratory work, screening methods for multiclass analysis can process a large number of samples in a short time. The main challenge is to develop a methodology to detect as many different classes of residues as possible, combined with
Mustufa Boxwalla et al.
Canadian journal of physiology and pharmacology, 88(5), 541-552 (2010-06-18)
Clonidine, an alpha2-adrenergic agonist, has been demonstrated to produce significant analgesia and potentiate morphine analgesia. Endothelin (ETA) receptor antagonists have also been found to potentiate the antinociceptive response to morphine. Clonidine and ET have been reported to have cardiovascular interactions
Abdullah D Altalhi et al.
Foodborne pathogens and disease, 7(3), 281-285 (2009-11-17)
The present study was carried out to screen and analyze the genetic characteristics of antibiotic resistance in Escherichia coli strains isolated from chicken meat marketed in the local markets of the Taif region in Saudi Arabia. A total of 119
Manthena V S Varma et al.
Journal of medicinal chemistry, 52(15), 4844-4852 (2009-05-19)
Kidney plays an important role in the elimination of drugs, especially with low or negligible hepatic clearance. An analysis of the interrelation of physicochemical properties and the human renal clearance for a data set of 391 drugs or compounds tested
Hanne T Soligard et al.
Pediatric research, 67(6), 614-618 (2010-03-11)
Ibuprofen binds to plasma albumin and could interfere with the binding of bilirubin in jaundiced newborn infants. Most clinical studies have not shown increased concentrations of unbound bilirubin (UB) in plasma from infants treated with ibuprofen for a patent ductus
High-throughput multiclass method for antibiotic residue analysis by liquid chromatography-tandem mass spectrometry
Chico J, et al.
Journal of Chromatography A, 1213(2), 189-199 (2008)
Quantitative analysis of twelve sulfonamides in honey after acidic hydrolysis by high-performance liquid chromatography with post-column derivatization and fluorescence detection
Maudens KE, et al.
Journal of Chromatography A, 1047(1), 85-92 (2004)
Helen Hurst et al.
Reproductive toxicology (Elmsford, N.Y.), 28(4), 503-510 (2009-08-04)
The chick micromass culture system has advantages over the validated rat system - ready availability and non-culling of the donor parent - but needs to give comparable results. This study confirmed comparability and the ability to extend the system to
Comprehensive fast multiresidue screening of 150 veterinary drugs in milk by ultra-performance liquid chromatography coupled to time of flight mass spectrometry
Ortelli D, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877(23), 2363-2374 (2009)
Tomoko Uchino et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 31(9), 1781-1790 (2008-10-31)
Pulmonary hypertension (PH) is a disease of unknown etiology that ultimately causes right ventricle heart failure with a lethal outcome. An increase in circulating endothelin (ET)-1 levels may contribute to disease progression. This study aimed to examine the possible effects
M Aslam et al.
Letters in applied microbiology, 50(3), 320-326 (2010-01-28)
To characterize antimicrobial resistance (AMR) and determine the seasonal prevalence of Escherichia coli O157:H7 isolated from commercial feedlots. Escherichia coli O157:H7 were isolated from faecal and oral samples collected at monthly intervals from three commercial feedlots over a 12-month period.
Husnain Syed et al.
Neurochemistry international, 48(8), 708-717 (2006-02-09)
Endothelins exert pathological effects in the eye and much interest centres on their role in causing retinal neuronal death in ischemic diseases like glaucoma. In the present study the influence of the non-selective endothelin antagonist, sulfisoxazole on raised intraocular pressure-induced
Charles E Ahlfors et al.
Clinica chimica acta; international journal of clinical chemistry, 365(1-2), 78-85 (2005-09-20)
Measuring plasma unbound bilirubin concentration by the peroxidase test is useful in the management of jaundiced newborns. However, the commercially available peroxidase technology is manual, and the unbound bilirubin may be seriously underestimated at the 42-fold sample dilution and single
Lourdes Santana et al.
Journal of medicinal chemistry, 51(21), 6740-6751 (2008-10-07)
The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared and assayed 33 coumarin derivatives
[Bacteriology and response to treatment with erythromycin-sulfisoxazole in children with acute otitis media].
R S Rodríguez et al.
Boletin medico del Hospital Infantil de Mexico, 44(12), 728-734 (1987-12-01)
Manthena V S Varma et al.
Journal of medicinal chemistry, 53(3), 1098-1108 (2010-01-15)
Oral bioavailability (F) is a product of fraction absorbed (Fa), fraction escaping gut-wall elimination (Fg), and fraction escaping hepatic elimination (Fh). In this study, using a database comprised of Fa, Fg, Fh, and F values for 309 drugs in humans
Zhichao Liu et al.
PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24)
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be translated
Y J Moon et al.
Research communications in molecular pathology and pharmacology, 108(3-4), 167-177 (2002-03-27)
Various factors most likely to influence the plasma protein binding of IQO4, a new isoquinolinedione derivative, to 4% human serum albumin (HSA) were evaluated using an equilibrium dialysis technique at an initial IQO4 concentration of 5 microg/ml. It took approximately
Sulfafurazole (sulphisoxazole).
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 24, 275-284 (1980-01-01)
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