CN
Search Within
330-14-3
应用筛选条件
关键词:'330-14-3'
显示 1-24 共 24 条结果 关于 "330-14-3" 范围 论文
K M Pumiglia et al.
The Journal of biological chemistry, 270(24), 14251-14254 (1995-06-16)
Raf-1 is a serine/threonine protein kinase positioned downstream of Ras in the mitogen-activated protein kinase cascade. Using a yeast two-hybrid strategy to identify other proteins that interact with and potentially regulate Raf-1, we isolated a clone encoding the carboxyl-terminal half
S P Robinson
Plant physiology, 79(4), 996-1002 (1985-12-01)
Spinach leaf chloroplasts isolated in isotonic media (330 millimolar sorbitol, -1.0 megapascals osmotic potential) had optimum rates of photosynthesis when assayed at -1.0 megapascals. When chloroplasts were isolated in hypertonic media (720 millimolar sorbitol, -2.0 megapascals osmotic potential) the optimum
María Teresa Magaña et al.
Blood cells, molecules & diseases, 39(2), 169-177 (2007-05-11)
We analyzed 112 beta(A) chromosomes from the Costa Chica region, with the aim of determining the 3' haplotype (3'Hp) in Afromestizo individuals and its relationship with the reported populations. Thirty polymorphic sites were identified by sequencing and two by restriction
Pavel A Savitsky et al.
The Journal of biological chemistry, 277(23), 20535-20540 (2002-04-02)
The Cdc25 family of dual specific phosphatases are critical components of cell cycle progression and checkpoint control. Certain stresses such as ultraviolet light stimulate the rapid and selective destruction of Cdc25A protein through a Chk1 protein kinase-dependent pathway. We demonstrate
Steven Q Wang et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 12(1), 197-202 (2012-10-04)
Excessive exposure from ultraviolet (UV) radiation contributes to the development of skin cancers and photoaging. Topical sunscreen products remain one of the most widely used forms of protection for the majority of the public. The objective of this analysis was
Debashis Sarker et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(1), 77-86 (2014-11-06)
This first-in-human dose-escalation trial evaluated the safety, tolerability, maximal-tolerated dose (MTD), dose-limiting toxicities (DLT), pharmacokinetics, pharmacodynamics, and preliminary clinical activity of pictilisib (GDC-0941), an oral, potent, and selective inhibitor of the class I phosphatidylinositol-3-kinases (PI3K). Sixty patients with solid tumors
Hiroko Tsujii et al.
European journal of medicinal chemistry, 45(6), 2191-2197 (2010-02-16)
3alpha-methoxyserrat-14-en-21beta-ol (1) and 3beta-methoxyserrat-14-en-21beta-ol (2) and their conjugates with curcumin, kojic acid, quercetin, and baicalein (3-18), as well as new analogs (19-24) derived from 1 and 2, were tested for their inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation
Jirí Kunes et al.
Farmaco (Societa chimica italiana : 1989), 57(9), 777-782 (2002-10-19)
The goal of this work was to shed more light on a preliminary finding about the relationship between the substitution in the thioacyl part of thiobenzanilides and their antituberculous effect. Thus, we prepared a set of 14 derivatives, out of
E V Chandrasekaran et al.
Biochemistry, 50(44), 9475-9487 (2011-09-15)
While glycosyltransferases are known to display unidirectional enzymatic activity, recent studies suggest that some can also catalyze readily reversible reactions. Recently, we found that mammalian sialyltransferase ST3Gal-II can catalyze the formation of CMP-NeuAc from 5'-CMP in the presence of a
Z Paszko et al.
Cancer investigation, 25(8), 742-749 (2007-12-07)
We aimed to investigate the occurrence and types of pathogenic mutations in the RET gene in patients with MTC of the Central Poland population and in their relatives. DNA was extracted from the peripheral blood lymphocytes of a total of
Y Y Tan et al.
Journal of autonomic pharmacology, 15(6), 421-436 (1995-12-01)
1. The effect of long-term treatment with the beta-adrenoceptor antagonists (--)-tertatolol and (--)-propranolol was studied. Sprague-Dawley rats were treated with either (--)-tertatolol (50 micrograms kg-1 hr-1), (--)-propranolol (250 micrograms kg-1 hr-1) or vehicle (1 mM HCl) for 14 days with
M E Hegi et al.
Carcinogenesis, 10(1), 43-47 (1989-01-01)
The 32P-postlabeling method has been adapted for the analysis of thymidine-cis-glycol-3'-phosphate (cis-dTGp,cis-5,6-dihydroxy-5,6-dihydrothymidine-3'-phosphat e). Cis-dTGp was isolated and purified from normal nucleotides by phenylboronate affinity chromatography and phosphorylated by T4 polynucleotide kinase in presence of 1 mM BeCl2 at pH 7.5.
Gerald A Matchett et al.
Brain research, 1136(1), 200-207 (2007-01-11)
Granulocyte-colony stimulating factor (G-CSF) is an endogenous peptide hormone of the hematopoietic system that has entered Phase I/II clinical trials for treatment of ischemic stroke. Severe intraoperative hypotension can lead to global cerebral ischemia and apoptotic neuron loss within the
M Noshiro et al.
Journal of biochemistry, 122(6), 1114-1121 (1998-03-14)
The structure of rat CYP51 gene encoding sterol 14-demethylase was examined. The CYP51 gene spanned about 18 kb and contained 10 exons. The copy number of CYP51 in the rat genome was determined to be one. In addition, one CYP51
C L Welch et al.
Journal of lipid research, 37(7), 1406-1421 (1996-07-01)
As part of an effort to dissect the genetic factors involved in cholesterol homeostasis in the mouse model, we report the mapping of 12 new candidate genes using linkage analysis. The genes include: cytoplasmic HMG-CoA synthase (Hmgcs 1, Chr 13)
Fatma Eker et al.
Journal of the American Chemical Society, 125(27), 8178-8185 (2003-07-03)
Determination of the precise solution structure of peptides is of utmost importance to the understanding of protein folding and peptide drugs. Herein, we have measured the UV circular dichroism (UVCD) spectra of tri-alanine dissolved in D(2)O, H(2)O, and glycerol. The
W Steudel et al.
American journal of respiratory and critical care medicine, 162(4 Pt 1), 1262-1267 (2000-10-13)
Nitric oxide (NO) is produced in the nasal cavities, airways, and lungs and is exhaled by normal animals and humans. Although increased exhaled NO concentrations in airway inflammation have been associated with increased airway expression of nitric oxide synthase 2
Reut Tomashov-Matar et al.
Journal of assisted reproduction and genetics, 29(7), 687-692 (2012-04-25)
To describe the identification of a new mutation responsible for causing human severe combined immunodeficiency syndrome (SCID). In a large consanguineous Israeli Arab family, this served as a diagnostic tool and enabled us to carry out preimplantation genetic diagnosis (PGD).
Akira Nishiyama et al.
Journal of hypertension, 21(10), 1897-1903 (2003-09-26)
Angiotensin II (Ang II)-dependent hypertension is associated with augmented intrarenal concentrations of Ang II; however, the distribution of the increased intrarenal Ang II has not been fully established. To determine the changes in renal interstitial fluid Ang II concentrations in
R F Cooke et al.
Journal of animal science, 90(9), 3266-3273 (2012-05-16)
Three experiments were conducted to evaluate plasma concentrations of glucose, insulin, IGF-I, and progesterone (P4) in pubertal beef heifers receiving exogenous glucose, insulin, or sometribove zinc. All heifers used had no luteal P4 synthesis but received a controlled internal drug-releasing
Anna Greppi et al.
Frontiers in microbiology, 11, 1166-1166 (2020-07-17)
Lactobacillus reuteri is a natural inhabitant of selected animal and human gastrointestinal tract (GIT). Certain strains have the capacity to transform glycerol to 3-hydroxypropionaldehyde (3-HPA), further excreted to form reuterin, a potent antimicrobial system. Reuterin-producing strains may be applied as
Se Joon Woo et al.
JAMA ophthalmology, 139(1), 68-76 (2020-11-20)
Neovascular age-related macular degeneration is the leading cause of blindness in individuals 50 years or older. The availability of a ranibizumab biosimilar product (SB11) may facilitate access to an effective alternative to this treatment. To demonstrate equivalence of efficacy, similar
Arnold J Weil et al.
Postgraduate medicine, 122(4), 158-169 (2010-08-03)
To assess the efficacy and tolerability of once-daily cyclobenzaprine extended release (CER) 15 and 30 mg in relieving acute muscle spasm. This is a pooled analysis of 2 randomized, double-blind, placebo-controlled, parallel-group studies of identical design. Adults with local muscle
Axel Maurice-Szamburski et al.
JAMA, 313(9), 916-925 (2015-03-04)
Sedative premedication is widely administered before surgery, but little clinical evidence supports its use. To assess the efficacy of sedative premedication on perioperative patient experience. A randomized clinical trial, the PremedX study, enrolled 1062 adult patients who were younger than
1/1