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Synthesis of aminomethylated 4-fluoropiperidines and 3-fluoropyrrolidines
Hende E, et al.
Organic & Biomolecular Chemistry, 8(11), 2509-2512 (2010)
Qinggang He et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 92, 52-57 (2014-07-08)
An electrochemical method with the ability to conduct (18)F-fluorination of aromatic molecules through direct nucleophilic fluorination of cationic intermediates is presented in this paper. The reaction was performed on a remote-controlled automatic platform. Nucleophilic electrochemical fluorination of tert-butyloxycarbonyl (Boc) protected
Willem Van Brabandt et al.
The Journal of organic chemistry, 71(18), 7100-7102 (2006-08-26)
N-(Alkylidene or 1-arylmethylidene)-2-propenylamines were regiospecifically functionalized to novel N-(alkylidene or 1-arylmethylidene)-3-bromo-2-fluoropropylamines, which were proven to be excellent precursors for 3-fluoroazetidines.
Saira Ashraf et al.
RNA biology, 16(10), 1377-1385 (2019-06-27)
N6-methyladenine is the most common covalent modification in cellular RNA species, with demonstrated functional consequences. At the molecular level this methylation could alter local RNA structure, and/or modulate the binding of specific proteins. We have previously shown that trans-Hoogsteen-sugar (sheared)
Aldrichimica Acta, 28, 31-31 (1995)
Lin Huang et al.
RNA (New York, N.Y.), 25(4), 423-430 (2019-01-06)
We have designed structure-based ligands for the guanidine-II riboswitch that bind with enhanced affinity, exploiting the twin binding sites created by loop-loop interaction. We synthesized diguanidine species, comprising two guanidino groups covalently connected by Cn linkers where n = 4
Marcus Gry Björklund et al.
Nucleic acids research, 36(4), 1334-1342 (2008-01-12)
DNA microarray technology has evolved dramatically in recent years, and is now a common tool in researchers' portfolios. The scope of the technique has expanded from small-scale studies to extensive studies such as classification of disease states. Technical knowledge regarding
Marilyne Sosson et al.
Nucleic acids research, 47(8), 3836-3845 (2019-03-15)
The template-directed formation of phosphodiester bonds between two nucleic acid components is a pivotal process in biology. To induce such a reaction in the absence of enzymes is a challenge. This challenge has been met for the extension of a
Recent advances in C-H fluorination
Lin A, et al.
Organic Chemistry Frontiers : An International Journal of Organic Chemistry / Royal Society of Chemistry, 1(4), 434-438 (2014)
Anders Foller Füchtbauer et al.
Scientific reports, 7(1), 2393-2393 (2017-05-26)
The bright fluorescent cytosine analogue tC
Héctor Aguilar-Bolados et al.
Journal of colloid and interface science, 524, 219-226 (2018-04-15)
The fluorination of two types of graphene oxides conducted by an easy and scalable deoxyfluorination reaction is reported. This reaction was carried out using diethylaminodifluorosulfinium tetrafluoroborate, a stable compound and an efficient reagent for replacing oxygenated functional groups of graphene
Effect of Partially Fluorinated N-Alkyl-Substituted Piperidine-2-carboxamides on Pharmacologically Relevant Properties
Vorberg R, et al.
ChemMedChem, 11(19), 2216-2239 (2016)
Synthesis and structure of stereoisomeric multivicinal hexafluoroalkanes
Hunter L, et al.
Angewandte Chemie (International ed. in English), 48(30), 5457-5460 (2009)
Saira Ashraf et al.
RNA (New York, N.Y.), 23(12), 1927-1935 (2017-09-29)
Folding properties differ markedly between kink-turns (k-turns) that have different biological functions. While ribosomal and riboswitch k-turns generally fold into their kinked conformation on addition of metal ions, box C/D snoRNP k-turns remain completely unfolded under these conditions, although they
Journal of Fluorine Chemistry, 126, 962-962 (2005)
Lin Huang et al.
EMBO reports, 18(9), 1631-1645 (2017-06-18)
N
Synthesis of 3-fluoroazetidines
Van Brabandt W, et al
The Journal of Organic Chemistry, 71(18), 7100-7102 (2006)
Improved synthesis of 9-(2, 3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl) adenine (FddA) using triethylamine trihydrofluoride.
Takamatsu S, et al.
Tetrahedron Letters, 42(12), 2321-2324 (2001)
Microwave-assisted aliphatic fluorine-chlorine exchange using triethylamine trihydrofluoride (TREAT-HF).
Kremsner JM, et al.
Tetrahedron Letters, 50(26), 3665-3668 (2009)
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